FR2376856A1 - Formes polymorphiques de ticrynafene, leur procede de preparation, et compositions pharmaceutiques en contenant - Google Patents
Formes polymorphiques de ticrynafene, leur procede de preparation, et compositions pharmaceutiques en contenantInfo
- Publication number
- FR2376856A1 FR2376856A1 FR7800007A FR7800007A FR2376856A1 FR 2376856 A1 FR2376856 A1 FR 2376856A1 FR 7800007 A FR7800007 A FR 7800007A FR 7800007 A FR7800007 A FR 7800007A FR 2376856 A1 FR2376856 A1 FR 2376856A1
- Authority
- FR
- France
- Prior art keywords
- ticrynafene
- pharmaceutical compositions
- preparation process
- compositions containing
- polymorphic forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000004048 modification Effects 0.000 abstract 3
- 238000012986 modification Methods 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 239000012454 non-polar solvent Substances 0.000 abstract 1
- 238000002076 thermal analysis method Methods 0.000 abstract 1
- AGHANLSBXUWXTB-UHFFFAOYSA-N tienilic acid Chemical compound ClC1=C(Cl)C(OCC(=O)O)=CC=C1C(=O)C1=CC=CS1 AGHANLSBXUWXTB-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB56277 | 1977-01-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2376856A1 true FR2376856A1 (fr) | 1978-08-04 |
| FR2376856B1 FR2376856B1 (en:Method) | 1981-01-23 |
Family
ID=9706556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7800007A Granted FR2376856A1 (fr) | 1977-01-07 | 1978-01-02 | Formes polymorphiques de ticrynafene, leur procede de preparation, et compositions pharmaceutiques en contenant |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5387349A (en:Method) |
| AU (1) | AU510569B2 (en:Method) |
| BE (1) | BE862688A (en:Method) |
| CH (1) | CH634066A5 (en:Method) |
| DD (1) | DD134096A5 (en:Method) |
| DE (1) | DE2800489A1 (en:Method) |
| DK (1) | DK565677A (en:Method) |
| ES (1) | ES465181A1 (en:Method) |
| FR (1) | FR2376856A1 (en:Method) |
| GR (1) | GR66062B (en:Method) |
| IL (1) | IL53651A0 (en:Method) |
| IT (1) | IT1089800B (en:Method) |
| LU (1) | LU78823A1 (en:Method) |
| NL (1) | NL7800213A (en:Method) |
| PL (1) | PL203865A1 (en:Method) |
| PT (1) | PT67416B (en:Method) |
| SE (1) | SE7714959L (en:Method) |
| ZA (1) | ZA777531B (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020939A1 (es) * | 1995-01-04 | 1996-07-11 | Ferrer Internacional, S.A. | POLYMORFOS B Y C DE MONONITRATO DE 1-[2,4-DICLORO-β-[(7-CLOROBENZO[b]TIEN-3-IL)METOXI]FENETIL]IMIDAZOL |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007064595A2 (en) * | 2005-11-29 | 2007-06-07 | Bausch & Lomb Incorporated | Fluocinolone acetonide drug substance polymorphic interconversion |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2115042A2 (en) * | 1970-11-25 | 1972-07-07 | Cerpha | 4-2-thienylketo-2,3-dichlorophenoxy acetic acid - prepn and purificn |
-
1977
- 1977-12-16 PT PT67416A patent/PT67416B/pt unknown
- 1977-12-17 ES ES465181A patent/ES465181A1/es not_active Expired
- 1977-12-19 AU AU31698/77A patent/AU510569B2/en not_active Expired
- 1977-12-19 ZA ZA00777531A patent/ZA777531B/xx unknown
- 1977-12-19 DK DK565677A patent/DK565677A/da not_active Application Discontinuation
- 1977-12-20 IL IL53651A patent/IL53651A0/xx unknown
- 1977-12-23 IT IT31205/77A patent/IT1089800B/it active
- 1977-12-26 JP JP15718977A patent/JPS5387349A/ja active Pending
- 1977-12-30 SE SE7714959A patent/SE7714959L/xx not_active Application Discontinuation
-
1978
- 1978-01-01 CH CH1612877A patent/CH634066A5/de not_active IP Right Cessation
- 1978-01-02 FR FR7800007A patent/FR2376856A1/fr active Granted
- 1978-01-04 GR GR55095A patent/GR66062B/el unknown
- 1978-01-04 DD DD78203100A patent/DD134096A5/xx unknown
- 1978-01-05 DE DE19782800489 patent/DE2800489A1/de not_active Withdrawn
- 1978-01-06 LU LU78823A patent/LU78823A1/xx unknown
- 1978-01-06 NL NL7800213A patent/NL7800213A/xx not_active Application Discontinuation
- 1978-01-06 BE BE184139A patent/BE862688A/xx not_active IP Right Cessation
- 1978-08-06 PL PL20386578A patent/PL203865A1/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2115042A2 (en) * | 1970-11-25 | 1972-07-07 | Cerpha | 4-2-thienylketo-2,3-dichlorophenoxy acetic acid - prepn and purificn |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996020939A1 (es) * | 1995-01-04 | 1996-07-11 | Ferrer Internacional, S.A. | POLYMORFOS B Y C DE MONONITRATO DE 1-[2,4-DICLORO-β-[(7-CLOROBENZO[b]TIEN-3-IL)METOXI]FENETIL]IMIDAZOL |
| AU691234B2 (en) * | 1995-01-04 | 1998-05-14 | Ferrer Internacional, S.A. | Process for preparing polymorphs B and C of 1- 2,4-dichloro -beta- (7-chlorobenzo b thien-3-yl)methoxy phenethyl imidazole mononitrate |
| US5939555A (en) * | 1995-01-04 | 1999-08-17 | Ferrer Internacional, S.A. | Polymorphs B and C of 1- 2,4-dichloro-β- (7-chlorobenzo b!thien-3-yl)methoxy!phenethyl!imidazole mononitrate |
Also Published As
| Publication number | Publication date |
|---|---|
| SE7714959L (sv) | 1978-07-08 |
| JPS5387349A (en) | 1978-08-01 |
| CH634066A5 (en) | 1983-01-14 |
| IL53651A0 (en) | 1978-03-10 |
| AU3169877A (en) | 1979-06-28 |
| PT67416A (en) | 1978-01-01 |
| AU510569B2 (en) | 1980-07-03 |
| FR2376856B1 (en:Method) | 1981-01-23 |
| DE2800489A1 (de) | 1978-07-13 |
| PL203865A1 (pl) | 1979-06-04 |
| BE862688A (fr) | 1978-07-06 |
| PT67416B (en) | 1979-05-22 |
| ZA777531B (en) | 1978-10-25 |
| LU78823A1 (fr) | 1978-06-09 |
| DK565677A (da) | 1978-07-08 |
| GR66062B (en:Method) | 1981-01-15 |
| DD134096A5 (de) | 1979-02-07 |
| IT1089800B (it) | 1985-06-18 |
| NL7800213A (nl) | 1978-07-11 |
| ES465181A1 (es) | 1979-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |