FR2372825A1 - Derives du bezimidazole et leur utilisation therapeutique comme hypotenseurs - Google Patents
Derives du bezimidazole et leur utilisation therapeutique comme hypotenseursInfo
- Publication number
- FR2372825A1 FR2372825A1 FR7736242A FR7736242A FR2372825A1 FR 2372825 A1 FR2372825 A1 FR 2372825A1 FR 7736242 A FR7736242 A FR 7736242A FR 7736242 A FR7736242 A FR 7736242A FR 2372825 A1 FR2372825 A1 FR 2372825A1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- bezimidazole
- hypotensors
- therapeutic use
- dimethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical class C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title 1
- WWITWDFTQWYARQ-UHFFFAOYSA-N 2-(5,6-dimethoxy-1h-benzimidazol-2-yl)-6,7-dimethoxy-3,4-dihydro-1h-isoquinoline Chemical compound COC1=C(OC)C=C2NC(N3CCC=4C=C(C(=CC=4C3)OC)OC)=NC2=C1 WWITWDFTQWYARQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 abstract 1
- 150000001556 benzimidazoles Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/746,656 US4088765A (en) | 1976-12-02 | 1976-12-02 | 5,6-Dimethoxy-2-heterocyclic benzimidazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2372825A1 true FR2372825A1 (fr) | 1978-06-30 |
| FR2372825B1 FR2372825B1 (cg-RX-API-DMAC7.html) | 1981-03-06 |
Family
ID=25001774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7736242A Granted FR2372825A1 (fr) | 1976-12-02 | 1977-12-01 | Derives du bezimidazole et leur utilisation therapeutique comme hypotenseurs |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4088765A (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5371081A (cg-RX-API-DMAC7.html) |
| CA (1) | CA1084933A (cg-RX-API-DMAC7.html) |
| FR (1) | FR2372825A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1573550A (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6867209B1 (en) | 1998-05-22 | 2005-03-15 | Scios, Inc. | Indole-type derivatives as inhibitors of p38 kinase |
| US6448257B1 (en) | 1998-05-22 | 2002-09-10 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
| US6589954B1 (en) * | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
| US6340685B1 (en) | 1998-05-22 | 2002-01-22 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
| US6130235A (en) * | 1998-05-22 | 2000-10-10 | Scios Inc. | Compounds and methods to treat cardiac failure and other disorders |
| IL146309A (en) | 1999-05-21 | 2008-03-20 | Scios Inc | Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38 |
| AU2007271243A1 (en) * | 2006-07-03 | 2008-01-10 | Neurosearch A/S | Combinations of monoamine reuptake inhibitors and potassium channel activators |
-
1976
- 1976-12-02 US US05/746,656 patent/US4088765A/en not_active Expired - Lifetime
-
1977
- 1977-11-17 CA CA291,154A patent/CA1084933A/en not_active Expired
- 1977-11-25 JP JP14079877A patent/JPS5371081A/ja active Pending
- 1977-12-01 FR FR7736242A patent/FR2372825A1/fr active Granted
- 1977-12-01 GB GB50132/77A patent/GB1573550A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1573550A (en) | 1980-08-28 |
| US4088765A (en) | 1978-05-09 |
| FR2372825B1 (cg-RX-API-DMAC7.html) | 1981-03-06 |
| JPS5371081A (en) | 1978-06-24 |
| CA1084933A (en) | 1980-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |