FR2371475A1 - Dispersion des fibres de collagene, son procede de preparation et ses applications - Google Patents

Dispersion des fibres de collagene, son procede de preparation et ses applications

Info

Publication number
FR2371475A1
FR2371475A1 FR7711470A FR7711470A FR2371475A1 FR 2371475 A1 FR2371475 A1 FR 2371475A1 FR 7711470 A FR7711470 A FR 7711470A FR 7711470 A FR7711470 A FR 7711470A FR 2371475 A1 FR2371475 A1 FR 2371475A1
Authority
FR
France
Prior art keywords
collagen fibers
dispersion
degrees
bundles
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7711470A
Other languages
English (en)
Other versions
FR2371475B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippi Inc
Original Assignee
Nippi Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippi Inc filed Critical Nippi Inc
Publication of FR2371475A1 publication Critical patent/FR2371475A1/fr
Application granted granted Critical
Publication of FR2371475B1 publication Critical patent/FR2371475B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • AHUMAN NECESSITIES
    • A22BUTCHERING; MEAT TREATMENT; PROCESSING POULTRY OR FISH
    • A22CPROCESSING MEAT, POULTRY, OR FISH
    • A22C13/00Sausage casings
    • A22C13/0013Chemical composition of synthetic sausage casings
    • A22C13/0016Chemical composition of synthetic sausage casings based on proteins, e.g. collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D69/00Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14Dynamic membranes
    • B01D69/141Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Dispersion Chemistry (AREA)
  • Artificial Filaments (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paper (AREA)
  • Materials For Medical Uses (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)

Abstract

L'invention a pour objet un procédé de préparation d'une dispersion aqueuse de fibres de collagène, caractérisé en ce qu'il consiste à tremper la matière de collagène dans une solution aqueuse 0,3 à 1,0 N en NaOH et contenant 10 à 25 % en poids de Na2 SO4 et 0,05 à 0,3 M d'une amine à une température comprise entre 15 et 25 degrés C pendant 5 heures à 10 jours; à laver à l'eau pour éliminer les sels de la matière trempée; à broyer mécaniquement la matière dans un milieu aqueux ayant un pH de 3,5 à 9,5 à une température inférieure à 25 degrés C pour obtenir des faisceaux de fibres de collagène; à tanner les faisceaux de fibres de collagène en les traitant dans une solution d'agent de tannage à une concentration comprise entre 0,005 et 10 % (poids/volume) à une température comprise entre 25 et 35 degrés C pendant 2 à 40 heures; et à broyer mécaniquement et à homogénéiser les faisceaux de fibres tannés à un pH compris entre 2,0 et 4,0 ou 9,0 à 11,0 pour obtenir une dispersion de fibres de collagène d'un diamètre de 4 à 12 microns et d'une longueur comprise entre 2 et 25 mm. La dispersion ainsi obtenue peut être utilisée pour la fabrication de divers articles conformés.
FR7711470A 1976-11-22 1977-04-15 Dispersion des fibres de collagene, son procede de preparation et ses applications Granted FR2371475A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14058276A JPS5365358A (en) 1976-11-22 1976-11-22 Collagen fiber dispersion

Publications (2)

Publication Number Publication Date
FR2371475A1 true FR2371475A1 (fr) 1978-06-16
FR2371475B1 FR2371475B1 (fr) 1979-03-23

Family

ID=15272033

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7711470A Granted FR2371475A1 (fr) 1976-11-22 1977-04-15 Dispersion des fibres de collagene, son procede de preparation et ses applications

Country Status (6)

Country Link
JP (1) JPS5365358A (fr)
DE (1) DE2716602C2 (fr)
ES (1) ES457823A1 (fr)
FR (1) FR2371475A1 (fr)
GB (1) GB1571561A (fr)
SE (1) SE421636B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2393581A1 (fr) * 1977-06-09 1979-01-05 Pikok Ind Trading Co Procede de preparation d'un pansement a base de collagene pour la peau, et pansements obtenus
FR2490647A2 (fr) * 1979-09-12 1982-03-26 Seton Co Procede de production d'un collagene macromoleculaire biologiquement actif et produit obtenu
FR2502943A1 (fr) * 1981-04-07 1982-10-08 Ufim I Glaznykh Bolezn Homotransplant pour keratoplastie lamellaire
EP0552576A1 (fr) * 1992-01-24 1993-07-28 Laboratoires Fournier S.A. Procédé de préparation de fibres de collagène

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625113A (en) * 1979-08-07 1981-03-10 Kureha Chem Ind Co Ltd Preparation of hemostatic collagen powder
US4406853A (en) 1980-02-28 1983-09-27 Collagen Development Corporation Method of preparation of regenerated fiber collagen condom
JPS61501153A (ja) * 1983-10-31 1986-06-12 シユミツト ラボラトリ−ズ インコ−ポレ−テツド コラ−ゲンゲルの製造法とそれから製造される膜製品
EP0306018A1 (fr) * 1987-09-04 1989-03-08 Bio-Products, Inc. Tendon/ligament de remplacement composé de fibres de tendons/ligaments longues, parallèles et non antisomatogènes
JPH02293495A (ja) * 1989-05-09 1990-12-04 Hokuetsu Paper Mills Ltd コラーゲン繊維を使用した歩留向上剤及びその製法
JPH0783759B2 (ja) * 1990-06-29 1995-09-13 株式会社高研 コラーゲン繊維止血材及びその製造方法
AU641784B2 (en) * 1990-08-08 1993-09-30 Showa Denko Kabushiki Kaisha Process for producing collagen powder
WO1994005702A1 (fr) * 1992-09-03 1994-03-17 Edmond Pharma Srl Extraction de collagene
DE69923342T2 (de) * 1998-11-17 2006-04-27 Hickory Specialities, Inc., Brentwood Verfahren zum beschichten eines lebensmittelproduktes mit kollagen
US6660829B1 (en) 2000-03-31 2003-12-09 Gennaro J. Maffia Collagen-based dispersions and macroporous structures
EP1852529A1 (fr) * 2006-05-04 2007-11-07 Alessandro Fratini Procédé d'extraction de fibres de collagène présente dans le derme de peaux d'animaux et un appareil permettant de mettre en oeuvre ce procédé
EP2727938B1 (fr) 2011-06-28 2017-03-29 Lanbide Heziketaren Lagunak, L.H.L Procédé d'obtention de collagène à partir de la peau d'un animal

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894132A (en) * 1973-09-10 1975-07-08 Leonard Daniel Method of forming collagen dispersions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5142234A (en) * 1974-10-05 1976-04-09 Yoshiharu Sato Jitenshatono yuatsudoryokuhatsuseisochi

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894132A (en) * 1973-09-10 1975-07-08 Leonard Daniel Method of forming collagen dispersions

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2393581A1 (fr) * 1977-06-09 1979-01-05 Pikok Ind Trading Co Procede de preparation d'un pansement a base de collagene pour la peau, et pansements obtenus
FR2490647A2 (fr) * 1979-09-12 1982-03-26 Seton Co Procede de production d'un collagene macromoleculaire biologiquement actif et produit obtenu
FR2502943A1 (fr) * 1981-04-07 1982-10-08 Ufim I Glaznykh Bolezn Homotransplant pour keratoplastie lamellaire
EP0552576A1 (fr) * 1992-01-24 1993-07-28 Laboratoires Fournier S.A. Procédé de préparation de fibres de collagène
FR2686612A1 (fr) * 1992-01-24 1993-07-30 Fournier Sca Laboratoires Procede de preparation de fibres de collagene.

Also Published As

Publication number Publication date
SE421636B (sv) 1982-01-18
SE7704253L (sv) 1978-05-23
FR2371475B1 (fr) 1979-03-23
JPS614419B2 (fr) 1986-02-10
JPS5365358A (en) 1978-06-10
GB1571561A (en) 1980-07-16
DE2716602B1 (de) 1978-02-02
ES457823A1 (es) 1978-08-16
DE2716602C2 (de) 1978-10-19

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