FR2371441A1 - Analogues de thromboxane - Google Patents
Analogues de thromboxaneInfo
- Publication number
- FR2371441A1 FR2371441A1 FR7805031A FR7805031A FR2371441A1 FR 2371441 A1 FR2371441 A1 FR 2371441A1 FR 7805031 A FR7805031 A FR 7805031A FR 7805031 A FR7805031 A FR 7805031A FR 2371441 A1 FR2371441 A1 FR 2371441A1
- Authority
- FR
- France
- Prior art keywords
- thromboxane
- analogues
- thromboxane analogues
- following formula
- field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003595 thromboxanes Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
La présente invention se situe dans le domaine des analogues de thromboxane. Elle concerne des composés répondant par exemple à la formule suivante :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/716,447 US4107427A (en) | 1976-08-20 | 1976-08-20 | Process and intermediates for preparing Thromboxane B1 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2371441A1 true FR2371441A1 (fr) | 1978-06-16 |
FR2371441B1 FR2371441B1 (fr) | 1981-12-24 |
Family
ID=24878028
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7711308A Granted FR2375236A1 (fr) | 1976-08-20 | 1977-04-14 | Analyse de thromboxane et son procede de preparation |
FR7805031A Granted FR2371441A1 (fr) | 1976-08-20 | 1978-02-22 | Analogues de thromboxane |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7711308A Granted FR2375236A1 (fr) | 1976-08-20 | 1977-04-14 | Analyse de thromboxane et son procede de preparation |
Country Status (6)
Country | Link |
---|---|
US (1) | US4107427A (fr) |
JP (1) | JPS5325523A (fr) |
CH (1) | CH633551A5 (fr) |
DE (1) | DE2716075A1 (fr) |
FR (2) | FR2375236A1 (fr) |
GB (2) | GB1534983A (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310705A (en) * | 1979-07-18 | 1982-01-12 | Basf Aktiengesellschaft | Preparation of higher unsaturated ketones |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4219483A (en) * | 1978-09-11 | 1980-08-26 | Pfizer Inc. | 4-Pyrone prostaglandin antagonists |
US4267315A (en) * | 1979-05-01 | 1981-05-12 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-11a-methano-TXA2 compounds |
US4313877A (en) * | 1979-05-01 | 1982-02-02 | The Upjohn Company | 11a-Methano TXA2 amides |
US4218378A (en) * | 1979-05-01 | 1980-08-19 | The Upjohn Company | 11a-Methano-TXA compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923861A (en) * | 1969-07-29 | 1975-12-02 | Upjohn Co | 3-Oxa prostaglandin F{331 -type compounds |
US3711515A (en) * | 1970-11-27 | 1973-01-16 | Upjohn Co | Tricyclic lactone alkene or alkenyne |
US3987087A (en) * | 1971-07-29 | 1976-10-19 | The Upjohn Company | Phenyl-substituted prostaglandin-f type analogs |
US3956284A (en) * | 1972-07-13 | 1976-05-11 | Pfizer Inc. | Heterocyclic 15-substituted-ω-pentanorprostoglandins |
US3931279A (en) * | 1973-05-21 | 1976-01-06 | The Upjohn Company | 5-Oxa prostaglandin F2.sub.α analogs |
-
1976
- 1976-08-20 US US05/716,447 patent/US4107427A/en not_active Expired - Lifetime
-
1977
- 1977-04-09 DE DE19772716075 patent/DE2716075A1/de not_active Withdrawn
- 1977-04-14 GB GB15551/77A patent/GB1534983A/en not_active Expired
- 1977-04-14 GB GB39564/77A patent/GB1534990A/en not_active Expired
- 1977-04-14 CH CH466877A patent/CH633551A5/de not_active IP Right Cessation
- 1977-04-14 JP JP4213977A patent/JPS5325523A/ja active Pending
- 1977-04-14 FR FR7711308A patent/FR2375236A1/fr active Granted
-
1978
- 1978-02-22 FR FR7805031A patent/FR2371441A1/fr active Granted
Non-Patent Citations (1)
Title |
---|
EXBK/77 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310705A (en) * | 1979-07-18 | 1982-01-12 | Basf Aktiengesellschaft | Preparation of higher unsaturated ketones |
Also Published As
Publication number | Publication date |
---|---|
CH633551A5 (de) | 1982-12-15 |
JPS5325523A (en) | 1978-03-09 |
FR2371441B1 (fr) | 1981-12-24 |
GB1534983A (en) | 1978-12-06 |
FR2375236A1 (fr) | 1978-07-21 |
US4107427A (en) | 1978-08-15 |
DE2716075A1 (de) | 1978-02-23 |
FR2375236B1 (fr) | 1982-07-09 |
GB1534990A (en) | 1978-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |