FR2370735A1 - Nouvelle synthese non asymetrique du tetramisole, du levamisole et derives correspondants - Google Patents

Nouvelle synthese non asymetrique du tetramisole, du levamisole et derives correspondants

Info

Publication number
FR2370735A1
FR2370735A1 FR7712567A FR7712567A FR2370735A1 FR 2370735 A1 FR2370735 A1 FR 2370735A1 FR 7712567 A FR7712567 A FR 7712567A FR 7712567 A FR7712567 A FR 7712567A FR 2370735 A1 FR2370735 A1 FR 2370735A1
Authority
FR
France
Prior art keywords
tetramisole
levamisole
new non
corresponding derivatives
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7712567A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/739,924 external-priority patent/US4090025A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FR2370735A1 publication Critical patent/FR2370735A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne une nouvelle synthèse non asymétrique du tétramisole, du levamisole et de leurs dérivés. Plus particulièrement, l'invention concerne la synthèse de composes 1,4-disubstitués de type DELTA 4-imidazolinone-2, imidazolidinone-2 ou imidazolidinethione-2 de formules suivantes :
FR7712567A 1976-04-26 1977-04-26 Nouvelle synthese non asymetrique du tetramisole, du levamisole et derives correspondants Withdrawn FR2370735A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68031176A 1976-04-26 1976-04-26
US05/739,924 US4090025A (en) 1976-04-26 1976-11-08 Intermediates for synthesis of tetramisole, levamisole and their derivatives

Publications (1)

Publication Number Publication Date
FR2370735A1 true FR2370735A1 (fr) 1978-06-09

Family

ID=27102431

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7712567A Withdrawn FR2370735A1 (fr) 1976-04-26 1977-04-26 Nouvelle synthese non asymetrique du tetramisole, du levamisole et derives correspondants

Country Status (14)

Country Link
JP (1) JPS52142067A (fr)
AU (1) AU2341277A (fr)
DD (1) DD131175A5 (fr)
DE (1) DE2718059A1 (fr)
DK (1) DK181177A (fr)
ES (1) ES458164A1 (fr)
FR (1) FR2370735A1 (fr)
GB (2) GB1579861A (fr)
IL (1) IL51654A0 (fr)
IT (1) IT1086883B (fr)
NL (1) NL7704424A (fr)
NO (1) NO771422L (fr)
NZ (1) NZ183622A (fr)
SE (1) SE7704745L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371433A1 (fr) * 1976-04-26 1978-06-16 American Cyanamid Co Nouvelles imidazolidinethiones optiquement actives, procede pour les preparer et application a la preparation du tetramizole et du levamisole optiquement actifs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726894A (en) * 1971-06-24 1973-04-10 American Cyanamid Co The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione
DE2349527A1 (de) * 1972-10-04 1974-04-18 Agfa Gevaert Ag Verfahren zur herstellung von flachdruckplatten
FR2258379A1 (en) * 1974-01-21 1975-08-18 Aries Robert Imidazo thiazolidine anthelmintics - prepd from an ethylene thiourea and a haloethanol, halogenation and cyclisation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3726894A (en) * 1971-06-24 1973-04-10 American Cyanamid Co The compound 1-(2-hydroxyethyl)-4-phenyl-2-imidazolidinethione
DE2349527A1 (de) * 1972-10-04 1974-04-18 Agfa Gevaert Ag Verfahren zur herstellung von flachdruckplatten
FR2258379A1 (en) * 1974-01-21 1975-08-18 Aries Robert Imidazo thiazolidine anthelmintics - prepd from an ethylene thiourea and a haloethanol, halogenation and cyclisation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371433A1 (fr) * 1976-04-26 1978-06-16 American Cyanamid Co Nouvelles imidazolidinethiones optiquement actives, procede pour les preparer et application a la preparation du tetramizole et du levamisole optiquement actifs

Also Published As

Publication number Publication date
ES458164A1 (es) 1978-08-16
DD131175A5 (de) 1978-06-07
IT1086883B (it) 1985-05-31
IL51654A0 (en) 1977-05-31
NO771422L (no) 1977-10-27
JPS52142067A (en) 1977-11-26
GB1579861A (en) 1980-11-26
AU2341277A (en) 1978-09-21
DE2718059A1 (de) 1977-11-10
SE7704745L (sv) 1977-10-27
NZ183622A (en) 1980-04-28
GB1579862A (en) 1980-11-26
DK181177A (da) 1977-10-27
NL7704424A (nl) 1977-10-28

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Legal Events

Date Code Title Description
ST Notification of lapse