FR2429783A1 - Nouveaux derives de vitamines d et leur application en therapeutique - Google Patents

Nouveaux derives de vitamines d et leur application en therapeutique

Info

Publication number
FR2429783A1
FR2429783A1 FR7920285A FR7920285A FR2429783A1 FR 2429783 A1 FR2429783 A1 FR 2429783A1 FR 7920285 A FR7920285 A FR 7920285A FR 7920285 A FR7920285 A FR 7920285A FR 2429783 A1 FR2429783 A1 FR 2429783A1
Authority
FR
France
Prior art keywords
vitamin
new
therapeutic application
syn
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7920285A
Other languages
English (en)
Other versions
FR2429783B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Institute for Medicine and Chemistry Inc
Original Assignee
Research Institute for Medicine and Chemistry Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Institute for Medicine and Chemistry Inc filed Critical Research Institute for Medicine and Chemistry Inc
Publication of FR2429783A1 publication Critical patent/FR2429783A1/fr
Application granted granted Critical
Publication of FR2429783B1 publication Critical patent/FR2429783B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L'invention concerne de nouveaux dérivés des vitamines D. L'invention a plus particulièrement pour objet les composés choisis parmi les épimères syn et anti de la 5,6-cis-10,19-dihydro-1 alpha -hydroxy vitamine D3 et leurs mélanges; les épimères syn et anti de la 5,6-trans-10,19-dihydro-1 alpha -hydroxy-vitamine D3 et leurs mélanges; les épimères syn et anti de la 5,6 trans-10,19-dihydro-1 alpha ,25 dihydroxy-vitamine D3 et leurs mélanges; et les épimères syn et anti de la 5,6-cis-10,19-dihydro-1 alpha ,25-dihydroxy-vitamine D3 et leurs mélanges.
FR7920285A 1976-06-03 1979-08-08 Nouveaux derives de vitamines d et leur application en therapeutique Granted FR2429783A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23036/76A GB1583749A (en) 1976-06-03 1976-06-03 Vitamin d derivatives

Publications (2)

Publication Number Publication Date
FR2429783A1 true FR2429783A1 (fr) 1980-01-25
FR2429783B1 FR2429783B1 (fr) 1981-05-08

Family

ID=10189072

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7716874A Granted FR2353529A1 (fr) 1976-06-03 1977-06-02 Preparation de derives de vitamines d
FR7920285A Granted FR2429783A1 (fr) 1976-06-03 1979-08-08 Nouveaux derives de vitamines d et leur application en therapeutique

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7716874A Granted FR2353529A1 (fr) 1976-06-03 1977-06-02 Preparation de derives de vitamines d

Country Status (21)

Country Link
US (1) US4159326A (fr)
JP (1) JPS5315356A (fr)
AU (1) AU517020B2 (fr)
BE (1) BE855326A (fr)
CA (1) CA1111435A (fr)
CH (1) CH629768A5 (fr)
DE (1) DE2724994A1 (fr)
DK (1) DK243477A (fr)
ES (1) ES459413A1 (fr)
FR (2) FR2353529A1 (fr)
GB (1) GB1583749A (fr)
IE (1) IE45627B1 (fr)
IL (1) IL52227A (fr)
IN (1) IN156431B (fr)
LU (1) LU77468A1 (fr)
MX (1) MX4820E (fr)
NL (1) NL7706056A (fr)
NO (1) NO771946L (fr)
NZ (1) NZ184288A (fr)
SE (1) SE7706469L (fr)
ZA (1) ZA773308B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
WO1992012165A1 (fr) * 1991-01-08 1992-07-23 Lunar Corporation PROCEDES DE PREPARATION ET UTILISATION DE LA VITAMINE 1α,24-DIHYDROXY D¿2?
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US6166000A (en) * 1991-01-08 2000-12-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2
US6251883B1 (en) 1991-01-08 2001-06-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
EP0614456B1 (fr) * 1992-08-28 1999-06-09 Bone Care International, Inc. Procedes de preparation et d'utilisation de la vitamine 1alpha,24(s)-dihydroxy d2
ATE227122T1 (de) * 1993-09-03 2002-11-15 Smithkline Beecham Corp Stabilisierte tablettenformulierung
DE29506819U1 (de) * 1995-04-28 1995-07-13 Groz-Beckert KG, 72458 Albstadt Barre mit Modulen für Tuftingwerkzeuge (II)
US6362350B1 (en) 1999-07-01 2002-03-26 Wisconsin Alumni Research Foundation Crystalline 1α, 24(S)-dihydroxyvitamin D2 and method of purification thereof
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049553A (en) * 1962-08-14 Process for the production of the reduc-
US2942009A (en) * 1956-02-14 1960-06-21 Philips Corp Method of reducing unsaturated compounds with an alkaline or alkalineearth metal in liquid ammonia
US3607888A (en) * 1969-08-07 1971-09-21 Wisconsin Alumni Res Found 25-hydroxytachysterol3 25-hydroxydihydrotachysterol3 and methods for preparing same
US3725489A (en) * 1969-10-02 1973-04-03 Allied Chem Hydrogenation of alkenes employing an organometallic hydrogenation catalyst
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
JPS5119752A (en) * 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho

Also Published As

Publication number Publication date
IL52227A0 (en) 1977-08-31
ZA773308B (en) 1978-07-26
NL7706056A (nl) 1977-12-06
US4159326A (en) 1979-06-26
IE45627L (en) 1977-12-03
IE45627B1 (en) 1982-10-20
CA1111435A (fr) 1981-10-27
AU2574977A (en) 1978-12-07
IN156431B (fr) 1985-08-03
GB1583749A (en) 1981-02-04
IL52227A (en) 1981-05-20
CH629768A5 (de) 1982-05-14
DE2724994A1 (de) 1977-12-15
BE855326A (fr) 1977-12-02
FR2429783B1 (fr) 1981-05-08
JPS5315356A (en) 1978-02-13
NZ184288A (en) 1980-08-26
FR2353529A1 (fr) 1977-12-30
DK243477A (da) 1977-12-04
LU77468A1 (fr) 1977-09-19
FR2353529B1 (fr) 1980-04-25
SE7706469L (sv) 1977-12-04
NO771946L (no) 1977-12-06
MX4820E (es) 1982-10-20
JPS625903B2 (fr) 1987-02-07
ES459413A1 (es) 1978-04-01
AU517020B2 (en) 1981-07-02

Similar Documents

Publication Publication Date Title
FR2416012A1 (fr) Derives de l'imidazole et medicament contenant ces substances
FR2429783A1 (fr) Nouveaux derives de vitamines d et leur application en therapeutique
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
FR2398748A1 (fr) Nouveaux derives d'imidazoquinazoline, leur preparation et leur application en tant que medicaments
DE69319440D1 (de) Herstellung von pharmazeutischen zusammensetzungen, die calcitonin enthalten
FR2436140A1 (fr) Derives de 1 a-hydroxy cyclovitamines du groupe d et leur preparation
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2364219A1 (fr) Derives de thiazolidine, leur procede de preparation et leur application en therapeutique
FR2387229A1 (fr) Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant
FR2372806A1 (fr) Pyrrolidones, leur procede de preparation et leur application therapeutique
FR2387988A1 (fr) Esters de cefuroxime, leur preparation et leur application therapeutique
FR2358382A1 (fr) Nouveaux nonapeptides, leurs procedes de preparation et compositions pharmaceutiques les contenant
FR2453151A1 (fr) Derives de la vitamine d3, leur procede de preparation et leur application en therapeutique
FR2429797A1 (fr)
FR2384745A1 (fr) Derives de la somatostatine et leur preparation
OA07537A (fr) Nouveaux dérivés du 4 H-1,2,4-triazole, leur préparation, leur application comme médicamment, les compositions les renfermant et les intermediaires obtenus.
FR2422405A1 (fr) Nouveaux medicaments constitues de derives de l'acide p-aminobenzoique
FR2415103A1 (fr) Acides et derives d'acides 4-pyridone-3-carboxyliques, leur preparation et leur application en tant que medicaments
BE900959A (fr) Derives furyles de prostaglandines 16-substituees et procede pour leur fabrication.
FR2367777A1 (fr) Derives de steroides, leur preparation et leurs utilisations therapeutiques
FR2370745A1 (fr) Nouveaux derives de la morphanthridine, leur preparation et leur application comme medicaments
FR2355012A1 (fr) Nouveaux derives de dihydro- et tetrahydro-iminothiazine, et leur application en tant que medicaments
FR2355831A1 (fr) Derives de benzazocine, leur procede de preparation et leur application therapeutique
FR2422667A1 (fr) Derives de 7a-methoxycephalosporine, leur procede de preparation et leur application en therapeutique
OA08165A (fr) Nouveaux dérivés thiosulfonates, leur procédé de préparation ainsi que les compositions pharmaceutiques les contenant.

Legal Events

Date Code Title Description
ST Notification of lapse