FR2369258A1 - Procede et composes intermediaires pour la dephtaloylation de phtalimido-azetidinones - Google Patents
Procede et composes intermediaires pour la dephtaloylation de phtalimido-azetidinonesInfo
- Publication number
- FR2369258A1 FR2369258A1 FR7732044A FR7732044A FR2369258A1 FR 2369258 A1 FR2369258 A1 FR 2369258A1 FR 7732044 A FR7732044 A FR 7732044A FR 7732044 A FR7732044 A FR 7732044A FR 2369258 A1 FR2369258 A1 FR 2369258A1
- Authority
- FR
- France
- Prior art keywords
- dephthaloylation
- phtalimido
- azetidinones
- intermediate compounds
- phthalimidoazetidinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
L'invention a pour objet un procédé de déphtaloylation d'une phtalimidoazétidinone, caractérisé en ce qu'on fait réagir la phtalimidoazétidinone avec une hydrazine dans laquelle la réactivité de l'hydrazine initiale est modifiée par monosubstitution par un radical organique ou formation d'un sel mobobasique, dans un solvant organique inerte dans lequel les réactifs sont solubles à la température de la réaction, à une température d'environ - 80 à 75 degrés C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/737,297 US4085100A (en) | 1976-11-01 | 1976-11-01 | Intermediate for dephthaloylation of azetidinone compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2369258A1 true FR2369258A1 (fr) | 1978-05-26 |
FR2369258B1 FR2369258B1 (fr) | 1980-06-20 |
Family
ID=24963353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7732044A Granted FR2369258A1 (fr) | 1976-11-01 | 1977-10-25 | Procede et composes intermediaires pour la dephtaloylation de phtalimido-azetidinones |
Country Status (7)
Country | Link |
---|---|
US (1) | US4085100A (fr) |
JP (1) | JPS5356696A (fr) |
DE (1) | DE2748258A1 (fr) |
FR (1) | FR2369258A1 (fr) |
GB (1) | GB1592878A (fr) |
IE (1) | IE45717B1 (fr) |
NL (1) | NL7711945A (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2515182A1 (fr) * | 1981-10-23 | 1983-04-29 | Roussel Uclaf | Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982001705A1 (fr) * | 1980-11-13 | 1982-05-27 | Takeda Chemical Industries Ltd | Derives 4-substitue-2-oxoazetidine et leur procede de preparation |
US4883869A (en) * | 1984-12-20 | 1989-11-28 | The Upjohn Company | Novel beta-lactams containing amino acid substituents |
DE3587308T2 (de) * | 1984-12-20 | 1993-08-19 | Upjohn Co | Monobactame. |
US5169945A (en) * | 1990-05-14 | 1992-12-08 | Eli Lilly And Company | Amino protecting group |
US5239069A (en) * | 1990-05-14 | 1993-08-24 | Eli Lilly And Company | Amino protecting group |
US5202344A (en) * | 1990-12-11 | 1993-04-13 | G. D. Searle & Co. | N-substituted lactams useful as cholecystokinin antagonists |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1935640A1 (de) * | 1968-07-23 | 1970-03-05 | Ciba Geigy | Alkenylmercaptoverbindungen |
GB1301720A (fr) * | 1970-05-08 | 1973-01-04 | ||
US3832347A (en) * | 1971-09-21 | 1974-08-27 | Lilly Co Eli | Imino-halides of 3-amido-2-halo-1-(1'-protected carboxy-2'-methyl-1'-propenyl)-4-azetidinones |
-
1976
- 1976-11-01 US US05/737,297 patent/US4085100A/en not_active Expired - Lifetime
-
1977
- 1977-10-17 GB GB43095/77A patent/GB1592878A/en not_active Expired
- 1977-10-25 FR FR7732044A patent/FR2369258A1/fr active Granted
- 1977-10-25 IE IE2172/77A patent/IE45717B1/en unknown
- 1977-10-25 JP JP12806977A patent/JPS5356696A/ja active Pending
- 1977-10-27 DE DE19772748258 patent/DE2748258A1/de not_active Withdrawn
- 1977-10-31 NL NL7711945A patent/NL7711945A/xx not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2515182A1 (fr) * | 1981-10-23 | 1983-04-29 | Roussel Uclaf | Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation |
Also Published As
Publication number | Publication date |
---|---|
FR2369258B1 (fr) | 1980-06-20 |
IE45717L (en) | 1978-05-01 |
JPS5356696A (en) | 1978-05-23 |
US4085100A (en) | 1978-04-18 |
GB1592878A (en) | 1981-07-08 |
IE45717B1 (en) | 1982-11-03 |
NL7711945A (nl) | 1978-05-03 |
DE2748258A1 (de) | 1978-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |