FR2366565A1 - Procede et appareil de chromatographie preparatoire a contre-courant avec une rangee de tubes en spirale tournant lentement - Google Patents
Procede et appareil de chromatographie preparatoire a contre-courant avec une rangee de tubes en spirale tournant lentementInfo
- Publication number
- FR2366565A1 FR2366565A1 FR7729130A FR7729130A FR2366565A1 FR 2366565 A1 FR2366565 A1 FR 2366565A1 FR 7729130 A FR7729130 A FR 7729130A FR 7729130 A FR7729130 A FR 7729130A FR 2366565 A1 FR2366565 A1 FR 2366565A1
- Authority
- FR
- France
- Prior art keywords
- row
- slow
- preparatory
- spiral tubes
- current chromatography
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/42—Flow patterns using counter-current
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
La présente invention est relative à un procédé et à un appareil de chromatographie préparatoire à contre-courant. L'appareil est caractérisé en ce qu'il comprend, en combinaison, un support, un cadre pivotant sur ce support, une colonne de séparation comprenant une rangée tubulaire hélicoïdale, des moyens de commande, des moyens d'alimentation et des moyens de contrôle du fluide. Application à la chromatographie préparatoire.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/727,864 US4051025A (en) | 1976-09-29 | 1976-09-29 | Preparative countercurrent chromatography with a slowly rotating helical tube array |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2366565A1 true FR2366565A1 (fr) | 1978-04-28 |
FR2366565B1 FR2366565B1 (fr) | 1983-07-22 |
Family
ID=24924390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7729130A Granted FR2366565A1 (fr) | 1976-09-29 | 1977-09-28 | Procede et appareil de chromatographie preparatoire a contre-courant avec une rangee de tubes en spirale tournant lentement |
Country Status (6)
Country | Link |
---|---|
US (1) | US4051025A (fr) |
JP (1) | JPS5811023B2 (fr) |
DE (1) | DE2741231C2 (fr) |
FR (1) | FR2366565A1 (fr) |
GB (1) | GB1553005A (fr) |
SE (1) | SE425053B (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4151089A (en) * | 1978-05-17 | 1979-04-24 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Device for high efficiency continuous countercurrent extraction using a rotating helical tube |
US4228950A (en) * | 1978-12-04 | 1980-10-21 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Horizontal flow-through coil planet centrifuge |
US4228009A (en) * | 1979-06-04 | 1980-10-14 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Toroidal coil planet centrifuge |
US4277017A (en) * | 1979-10-11 | 1981-07-07 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Gear drive for seal-less counter current chromatography |
US4422941A (en) * | 1980-09-08 | 1983-12-27 | University Of Pittsburgh | Apparatus for liquid-solid column centrifugation chromatography and method |
US4321138A (en) * | 1981-02-02 | 1982-03-23 | The United States Of America As Represented By The Department Of Health And Human Services | Method and apparatus for preparative countercurrent chromatography employing a rotating column assembly |
ATE39321T1 (de) * | 1982-08-14 | 1989-01-15 | Utzinger Gustav E | Fluessigkeitsverspruehungsvorrichtung. |
JPS5962312A (ja) * | 1982-09-30 | 1984-04-09 | Sanki Eng Kk | 生理活性天然有機化合物の精製方法及び装置 |
US4532039A (en) * | 1983-03-14 | 1985-07-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Multi-layer coil assembly coaxially mounted around the rotary axis for preparatory countercurrent chromatography |
US4551251A (en) * | 1984-03-06 | 1985-11-05 | The United States Of America As Represented By The Department Of Health And Human Services | Monolithic integrated flow circuit |
US4720462A (en) * | 1985-11-05 | 1988-01-19 | Robert Rosenson | Culture system for the culture of solid tissue masses and method of using the same |
US4714554A (en) * | 1986-10-03 | 1987-12-22 | The United States Of America As Represented By The Department Of Health And Human Services | Cross-axis synchronous flow-through coil planet centrifuge free of rotary seals: apparatus and method for performing countercurrent chromatography |
US4792395A (en) * | 1987-08-14 | 1988-12-20 | Lee David Y W | High speed countercurrent centrifuge for removal attachment of chromatographic columns thereto, and chromatographic column for the same |
US4968428A (en) * | 1987-11-13 | 1990-11-06 | Sanki Engineering, Ltd. | Centrifugal counter-current distribution chromatography |
US4877523A (en) * | 1987-11-13 | 1989-10-31 | Sanki Engineering, Ltd. | Centrifugal counter-current distribution chromatography |
AU6956091A (en) * | 1989-12-13 | 1991-07-18 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Improved apparatus for countercurrent chromatography separations and stable methods for monitoring the effluent thereof |
US5169521A (en) * | 1989-12-13 | 1992-12-08 | The United States Of America As Represented By The Department Of Health And Human Services | Apparatus for countercurrent chromatography separations |
US5104531A (en) * | 1990-02-26 | 1992-04-14 | The United States Of America As Represented By The Department Of Health And Human Services | Cross-axis synchronous flow through coil planet centrifuge for large scale preparative countercurrent chromatography |
US5354473A (en) * | 1992-09-18 | 1994-10-11 | The United States Of America As Represented By The Departent Of Health And Human Services | Method for concentrating a solute by countercurrent chromatography |
DE10028611A1 (de) * | 2000-06-09 | 2001-12-20 | Pika Weihenstephan Gmbh | Verfahren zur Phasentrennung |
FR2852104B1 (fr) * | 2003-03-06 | 2005-05-13 | Partus Technologies | Dispositif tournant pour chromatographe de partage centrifuge |
FR2856933B1 (fr) * | 2003-07-02 | 2005-08-19 | Inst Francais Du Petrole | Procede et dispositif de separation des constituants d'une charge liquide par chromatographie liquide-liquide centrifuge |
JP5048477B2 (ja) * | 2004-03-05 | 2012-10-17 | ウオーターズ・テクノロジーズ・コーポレイシヨン | カラム又はカートリッジを検出器近傍に保持するための装置及び該装置を使用する方法 |
DE102006028129B4 (de) * | 2006-06-15 | 2008-07-03 | Nikolaus Stephan Pfeiffer | Kontinuierliche Gegenstom Chromatographie Anlage |
US8062898B2 (en) * | 2006-10-20 | 2011-11-22 | The Board Of Trustees Of The University Of Illinois | Selection and rational development of solvent systems in counter-current chromatograph |
US8175817B2 (en) * | 2007-01-03 | 2012-05-08 | The Board Of Trustees Of The University Of Illinois | Reciprocal symmetry plots as a new representation of countercurrent chromatograms |
GB2446129B (en) * | 2007-02-02 | 2009-06-10 | Dynamic Extractions Ltd | Non-synchronous drive for centrifuges |
US10512910B2 (en) | 2008-09-23 | 2019-12-24 | Bio-Rad Laboratories, Inc. | Droplet-based analysis method |
US9417190B2 (en) | 2008-09-23 | 2016-08-16 | Bio-Rad Laboratories, Inc. | Calibrations and controls for droplet-based assays |
US9156010B2 (en) | 2008-09-23 | 2015-10-13 | Bio-Rad Laboratories, Inc. | Droplet-based assay system |
US8633015B2 (en) | 2008-09-23 | 2014-01-21 | Bio-Rad Laboratories, Inc. | Flow-based thermocycling system with thermoelectric cooler |
CN102405402A (zh) * | 2008-09-23 | 2012-04-04 | 阔达生命有限公司 | 基于液滴的测定系统 |
US12090480B2 (en) | 2008-09-23 | 2024-09-17 | Bio-Rad Laboratories, Inc. | Partition-based method of analysis |
US8951939B2 (en) | 2011-07-12 | 2015-02-10 | Bio-Rad Laboratories, Inc. | Digital assays with multiplexed detection of two or more targets in the same optical channel |
US9764322B2 (en) | 2008-09-23 | 2017-09-19 | Bio-Rad Laboratories, Inc. | System for generating droplets with pressure monitoring |
US9132394B2 (en) | 2008-09-23 | 2015-09-15 | Bio-Rad Laboratories, Inc. | System for detection of spaced droplets |
US11130128B2 (en) | 2008-09-23 | 2021-09-28 | Bio-Rad Laboratories, Inc. | Detection method for a target nucleic acid |
US9492797B2 (en) | 2008-09-23 | 2016-11-15 | Bio-Rad Laboratories, Inc. | System for detection of spaced droplets |
US8709762B2 (en) | 2010-03-02 | 2014-04-29 | Bio-Rad Laboratories, Inc. | System for hot-start amplification via a multiple emulsion |
CA3021714C (fr) | 2009-09-02 | 2021-03-09 | Bio-Rad Laboratories, Inc. | Systeme de melange de fluides par coalescence d'emulsions multiples |
US8399198B2 (en) * | 2010-03-02 | 2013-03-19 | Bio-Rad Laboratories, Inc. | Assays with droplets transformed into capsules |
CA2767113A1 (fr) | 2010-03-25 | 2011-09-29 | Bio-Rad Laboratories, Inc. | Systeme de detection pour analyses a base de gouttelettes |
JP2013524171A (ja) | 2010-03-25 | 2013-06-17 | クァンタライフ・インコーポレーテッド | 液滴ベースのアッセイのための液滴の発生 |
CA2767114A1 (fr) | 2010-03-25 | 2011-09-29 | Bio-Rad Laboratories, Inc. | Systeme de transport de gouttelettes a des fins de detection |
CA3215088A1 (fr) | 2010-11-01 | 2012-05-10 | Bio-Rad Laboratories, Inc. | Systeme de formation d'emulsions |
US12097495B2 (en) | 2011-02-18 | 2024-09-24 | Bio-Rad Laboratories, Inc. | Methods and compositions for detecting genetic material |
JP2014509865A (ja) | 2011-03-18 | 2014-04-24 | バイオ−ラッド・ラボラトリーズ・インコーポレーテッド | シグナルの組合せ使用による多重化デジタルアッセイ |
WO2013019751A1 (fr) | 2011-07-29 | 2013-02-07 | Bio-Rad Laboratories, Inc., | Caractérisation de banque par essai numérique |
WO2013155531A2 (fr) | 2012-04-13 | 2013-10-17 | Bio-Rad Laboratories, Inc. | Porte-éprouvette ayant un puits qui comporte un promoteur d'effet de mèche |
CN108367256B (zh) * | 2015-09-22 | 2022-02-25 | 怀亚特技术公司 | 测量来自液体样品的多个信号的方法和装置 |
US10675558B2 (en) | 2016-04-20 | 2020-06-09 | The Hong Kong University Of Science And Technology | Dispersed mobile-phase countercurrent chromatography |
CN107812394B (zh) * | 2017-10-24 | 2020-04-14 | 湖北民族大学 | 药用植物有效成分提取装置 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3775309A (en) * | 1972-07-27 | 1973-11-27 | Department Of Health Education | Countercurrent chromatography with flow-through coil planet centrifuge |
US3856669A (en) * | 1973-07-02 | 1974-12-24 | Department Of Health Education | Elution centrifuge-apparatus and method |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3038326A (en) * | 1958-06-02 | 1962-06-12 | Phillips Petroleum Co | Chromatographic analyzer |
US3617557A (en) * | 1968-10-15 | 1971-11-02 | Reeve Angel & Co Ltd H | Preparative separation of fluid samples |
JPS4925239A (fr) * | 1972-06-30 | 1974-03-06 | ||
JPS4979596A (fr) * | 1972-12-06 | 1974-08-01 |
-
1976
- 1976-09-29 US US05/727,864 patent/US4051025A/en not_active Expired - Lifetime
-
1977
- 1977-08-24 GB GB35580/77A patent/GB1553005A/en not_active Expired
- 1977-09-07 SE SE7710004A patent/SE425053B/xx not_active IP Right Cessation
- 1977-09-13 DE DE2741231A patent/DE2741231C2/de not_active Expired
- 1977-09-26 JP JP52115464A patent/JPS5811023B2/ja not_active Expired
- 1977-09-28 FR FR7729130A patent/FR2366565A1/fr active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3775309A (en) * | 1972-07-27 | 1973-11-27 | Department Of Health Education | Countercurrent chromatography with flow-through coil planet centrifuge |
US3856669A (en) * | 1973-07-02 | 1974-12-24 | Department Of Health Education | Elution centrifuge-apparatus and method |
Non-Patent Citations (1)
Title |
---|
ANALYTICAL CHEMISTRY, vol. 43, no. 13, novembre 1971, Y ITO: 'Countercurrent chromatography', pages 69A - 75A * |
Also Published As
Publication number | Publication date |
---|---|
JPS5811023B2 (ja) | 1983-03-01 |
DE2741231C2 (de) | 1987-02-26 |
US4051025A (en) | 1977-09-27 |
DE2741231A1 (de) | 1978-04-06 |
SE425053B (sv) | 1982-08-30 |
GB1553005A (en) | 1979-09-19 |
SE7710004L (sv) | 1978-03-30 |
FR2366565B1 (fr) | 1983-07-22 |
JPS5383683A (en) | 1978-07-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
ST | Notification of lapse |