FR2366294A1 - Composes de la rifamycine ayant une activite anti-bacterienne - Google Patents

Composes de la rifamycine ayant une activite anti-bacterienne

Info

Publication number
FR2366294A1
FR2366294A1 FR7726223A FR7726223A FR2366294A1 FR 2366294 A1 FR2366294 A1 FR 2366294A1 FR 7726223 A FR7726223 A FR 7726223A FR 7726223 A FR7726223 A FR 7726223A FR 2366294 A1 FR2366294 A1 FR 2366294A1
Authority
FR
France
Prior art keywords
rifamycin
bacterial activity
compounds
rifamycin compounds
aminosubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7726223A
Other languages
English (en)
Other versions
FR2366294B1 (fr
Inventor
Vittorio Rossetti
Leonardo Marsili
Carmine Pasqualucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ARCHIFAR IND CHIM TRENTINO
Original Assignee
ARCHIFAR IND CHIM TRENTINO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ARCHIFAR IND CHIM TRENTINO filed Critical ARCHIFAR IND CHIM TRENTINO
Publication of FR2366294A1 publication Critical patent/FR2366294A1/fr
Application granted granted Critical
Publication of FR2366294B1 publication Critical patent/FR2366294B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composés de rifamycine ayant une activité anti-bactérienne élevée, constitués de 3-aminosubstitués-4-desoxo-4-imino-rifamycine S dérivés. Lesdits composés sont des poudres de couleur rouge-violet et sont obtenus par réaction de la 3-aminosubstituée-rifamycine S avec de l'ammoniac gazeux.
FR7726223A 1976-09-30 1977-08-29 Composes de la rifamycine ayant une activite anti-bacterienne Granted FR2366294A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT520976 1976-09-30

Publications (2)

Publication Number Publication Date
FR2366294A1 true FR2366294A1 (fr) 1978-04-28
FR2366294B1 FR2366294B1 (fr) 1982-11-19

Family

ID=11119379

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7726222A Granted FR2366296A1 (fr) 1976-09-30 1977-08-29 Composes antibiotiques de rifamycine
FR7726221A Granted FR2366295A1 (fr) 1976-09-30 1977-08-29 Composes bactericides de la rifamycine
FR7726223A Granted FR2366294A1 (fr) 1976-09-30 1977-08-29 Composes de la rifamycine ayant une activite anti-bacterienne

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FR7726222A Granted FR2366296A1 (fr) 1976-09-30 1977-08-29 Composes antibiotiques de rifamycine
FR7726221A Granted FR2366295A1 (fr) 1976-09-30 1977-08-29 Composes bactericides de la rifamycine

Country Status (12)

Country Link
US (3) US4175077A (fr)
JP (3) JPS5350200A (fr)
AT (2) AT352278B (fr)
CA (2) CA1081218A (fr)
CH (3) CH629496A5 (fr)
DE (3) DE2739671A1 (fr)
DK (2) DK345977A (fr)
ES (2) ES462293A1 (fr)
FR (3) FR2366296A1 (fr)
GB (3) GB1550769A (fr)
NL (2) NL7710625A (fr)
SE (2) SE7708841L (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633014A5 (en) * 1978-06-09 1982-11-15 Erba Farmitalia Rifamycin compounds
BE886395A (fr) * 1980-02-13 1981-03-16 Erba Farmitalia Derives de rifamycine
IT1154655B (it) * 1980-05-22 1987-01-21 Alfa Farmaceutici Spa Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica
DD204925A5 (de) * 1980-09-25 1983-12-14 Ciba Geigy Ag Verfahren zur herstellung eines 4-aminoimidazolo (4,5-c)rifamycins sv oder s
JPS5767489A (en) * 1980-10-16 1982-04-24 Tokyo Shibaura Electric Co Winch for elevator
IT1201963B (it) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa Derivati delle rifamicine e procedimento per la loro preparazione
US5362726A (en) * 1993-02-12 1994-11-08 Healthsearch, Inc. Compound and method of treatment for falciparum malaria
JP2005510534A (ja) * 2001-11-21 2005-04-21 アクティブバイオティクス インコーポレイティッド 標的化治療薬およびその使用
PT102807A (pt) * 2002-07-09 2004-01-30 Inst Nac De Engenharia E Tecno Derivados n-substituidos de rifabutina uteis como agentes antimicrobianos, processo para a sua preparacao e sua utilizacao como medicamentos
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US7256187B2 (en) * 2004-03-10 2007-08-14 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime derivatives effective against drug-resistant microbes
US7265107B2 (en) * 2004-03-10 2007-09-04 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes
WO2008008480A2 (fr) * 2006-07-12 2008-01-17 Cumbre Pharmaceuticals Inc. Dérivés de rifamycine contenant du nitrohétéroaryl
US7884099B2 (en) * 2007-11-16 2011-02-08 Cumbre Ip Ventures, L.P. Quinolone carboxylic acid-substituted rifamycin derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311018A1 (fr) * 1975-05-15 1976-12-10 Archifar Ind Chim Trentino Nouveaux composes de rifamycine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH512510A (de) * 1965-08-24 1971-09-15 Ciba Geigy Ag Verfahren zur Herstellung von in 3-Stellung durch eine unsubstituierte oder substituierte Aminogruppe substituierten Derivaten von Rifamycin-S und Rifamycin-SV
CH536851A (de) * 1966-10-25 1973-05-15 Ciba Geigy Ag Verfahren zur Herstellung neuer antibiotisch wirksamer Verbindungen der Rifamycinreihen
IT1056271B (it) * 1975-05-20 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche
IT1056272B (it) * 1975-06-13 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311018A1 (fr) * 1975-05-15 1976-12-10 Archifar Ind Chim Trentino Nouveaux composes de rifamycine

Also Published As

Publication number Publication date
DE2739623A1 (de) 1978-04-06
CA1083144A (fr) 1980-08-05
DK357477A (da) 1978-03-31
GB1560265A (en) 1980-02-06
SE7709001L (sv) 1978-03-31
SE7708841L (sv) 1978-03-31
FR2366296A1 (fr) 1978-04-28
DK345977A (da) 1978-03-31
JPS5350198A (en) 1978-05-08
US4165317A (en) 1979-08-21
DE2739624A1 (de) 1978-04-06
ATA649177A (de) 1979-02-15
AT352278B (de) 1979-09-10
FR2366294B1 (fr) 1982-11-19
FR2366295B1 (fr) 1982-11-19
FR2366296B1 (fr) 1982-11-19
ES462293A1 (es) 1978-05-16
AT352279B (de) 1979-09-10
ES462294A1 (es) 1978-05-16
CA1081218A (fr) 1980-07-08
FR2366295A1 (fr) 1978-04-28
ATA649077A (de) 1979-02-15
GB1557090A (en) 1979-12-05
JPS5526145B2 (fr) 1980-07-11
JPS5350199A (en) 1978-05-08
NL7710627A (nl) 1978-04-03
CH629498A5 (it) 1982-04-30
DE2739671A1 (de) 1978-04-06
CH629497A5 (it) 1982-04-30
US4164499A (en) 1979-08-14
NL7710625A (nl) 1978-04-03
CH629496A5 (it) 1982-04-30
JPS5350200A (en) 1978-05-08
JPS5526146B2 (fr) 1980-07-11
US4175077A (en) 1979-11-20
GB1550769A (en) 1979-08-22

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse