FR2365572B1 - - Google Patents
Info
- Publication number
- FR2365572B1 FR2365572B1 FR7728627A FR7728627A FR2365572B1 FR 2365572 B1 FR2365572 B1 FR 2365572B1 FR 7728627 A FR7728627 A FR 7728627A FR 7728627 A FR7728627 A FR 7728627A FR 2365572 B1 FR2365572 B1 FR 2365572B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72718476A | 1976-09-27 | 1976-09-27 | |
US05/825,612 US4263311A (en) | 1976-09-27 | 1977-08-18 | 5,6-Phenyl-2,3-dihydroimidazo [2,1-b] thiazoles |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2365572A1 FR2365572A1 (fr) | 1978-04-21 |
FR2365572B1 true FR2365572B1 (e) | 1980-11-28 |
Family
ID=27111468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7728627A Granted FR2365572A1 (fr) | 1976-09-27 | 1977-09-22 | Nouveaux 2,3-dihydro imidazo (2,1-b) thiazoles, leur procede de preparation et leur application en therapeutique |
Country Status (18)
Country | Link |
---|---|
US (1) | US4263311A (e) |
JP (1) | JPS5340797A (e) |
AU (1) | AU2882977A (e) |
DD (1) | DD132587A5 (e) |
DE (1) | DE2742725A1 (e) |
DK (1) | DK406077A (e) |
ES (1) | ES462445A1 (e) |
FI (1) | FI772829A (e) |
FR (1) | FR2365572A1 (e) |
GR (1) | GR63698B (e) |
IT (1) | IT1143693B (e) |
LU (1) | LU78172A1 (e) |
NL (1) | NL7710528A (e) |
NO (1) | NO773296L (e) |
NZ (1) | NZ185169A (e) |
PL (1) | PL201082A1 (e) |
PT (1) | PT67046B (e) |
SE (1) | SE7710762L (e) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU77703A1 (de) * | 1977-07-07 | 1979-03-26 | Ciba Geigy Ag | Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen |
US4175127A (en) * | 1978-09-27 | 1979-11-20 | Smithkline Corporation | Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles |
PL221188A1 (e) * | 1979-01-05 | 1980-12-01 | Ciba Geigy Ag | |
JPS5687553A (en) * | 1979-11-23 | 1981-07-16 | Sandoz Ag | Improved alkylation |
NO811630L (no) * | 1980-05-29 | 1981-11-30 | Bayer Ag | Imidazoazolalkensyreamider, nye mellomprodukter for deres fremstilling, deres fremstilling og deres anvendelse som legemiddel |
JPS59172328A (ja) * | 1983-03-16 | 1984-09-29 | Hitachi Ltd | スラリ−連続圧送装置 |
US4751310A (en) * | 1985-12-12 | 1988-06-14 | Smithkline Beckman Corporation | Inhibition of the 5-lipoxygenase pathway |
US5002941A (en) * | 1985-12-12 | 1991-03-26 | Smithkline Beecham Corporation | Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors |
ZW24186A1 (en) * | 1985-12-12 | 1987-07-08 | Smithkline Beckman Corp | Inhibition of the 5-lipoxygenase pathway |
US5145858A (en) * | 1985-12-12 | 1992-09-08 | Smithkline Beecham Corp. | Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors |
US4719218A (en) * | 1985-12-12 | 1988-01-12 | Smithkline Beckman Corporation | Pyrrolo[1,2-a]imidazole and pyrrolo[1,2-a]pyridine derivatives and their use as 5-lipoxygenase pathway inhibitor |
US5134150A (en) * | 1985-12-12 | 1992-07-28 | Smithkline Beecham Corporation | Inhibition of the 5-lipoxygenase pathway |
US4794114A (en) * | 1986-08-19 | 1988-12-27 | Smithkline Beckman Corporation | Inhibition of interleukin-1 production by monocytes and/or macrophages |
JP2816224B2 (ja) * | 1990-03-16 | 1998-10-27 | 株式会社日立製作所 | 多筒式水ピストン型流体圧送装置 |
US5935978A (en) * | 1991-01-28 | 1999-08-10 | Rhone-Poulenc Rorer Limited | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- or heteroatom-containing linking group |
GB9311281D0 (en) * | 1993-06-01 | 1993-07-21 | Rhone Poulenc Rorer Ltd | Novel composition of matter |
US5698711A (en) | 1991-01-28 | 1997-12-16 | Rhone-Poulenc Rorer Limited | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- or heteroatom-containing linking group |
US5679696A (en) * | 1992-07-28 | 1997-10-21 | Rhone-Poulenc Rorer Limited | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic-or heteroatom-containing linking group |
US5552422A (en) * | 1995-01-11 | 1996-09-03 | Merck Frosst Canada, Inc. | Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents |
CN109748831A (zh) * | 2018-12-17 | 2019-05-14 | 南通正达农化有限公司 | 一种三氟甲磺酸三氟乙酯的制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2969369A (en) * | 1959-10-23 | 1961-01-24 | Searle & Co | Derivatives of 3-phenyl-5, 6-dihydroimidazo-[2. 1-b] thiazoles |
NL129432C (e) * | 1964-02-29 | |||
NL131034C (e) * | 1964-05-11 | |||
US4059588A (en) * | 1965-07-19 | 1977-11-22 | Ici Australia Limited | Process for preparing 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole |
US3455924A (en) * | 1967-02-08 | 1969-07-15 | Upjohn Co | Dianisylimidazoles |
NL164285C (nl) * | 1968-01-09 | 1980-12-15 | Rhone Poulenc Sa | Werkwijze ter bereiding van een farmaceutisch preparaat, dat een imidazoÿ2.1-bÿthiazoolderivaat bevat, de gevormde farmaceutische preparaten, alsmede werkwijze voor het bereiden van dit imidazoÿ2.1-bÿthiazoolderivaat. |
US3732215A (en) * | 1971-02-08 | 1973-05-08 | Squibb & Sons Inc | Imidazole derivatives |
HU169255B (e) * | 1973-06-20 | 1976-10-28 | ||
US3895021A (en) * | 1973-09-04 | 1975-07-15 | Smithkline Corp | N-heterocyclic pulvinic acid amides |
FR2271213A1 (en) * | 1974-05-16 | 1975-12-12 | Aries Robert | Tetramisole anthelmintics prepn. - by reaction of ethylene thiourea with vinyl halide and base |
GB1541321A (en) * | 1976-03-10 | 1979-02-28 | Metabio | 2,3-dihydroimidazo(2,1-b)thiazole derivatives and process for their preparation |
-
1977
- 1977-08-18 US US05/825,612 patent/US4263311A/en not_active Expired - Lifetime
- 1977-09-12 NZ NZ185169A patent/NZ185169A/xx unknown
- 1977-09-13 DK DK406077A patent/DK406077A/da unknown
- 1977-09-15 AU AU28829/77A patent/AU2882977A/en active Pending
- 1977-09-17 ES ES462445A patent/ES462445A1/es not_active Expired
- 1977-09-19 PT PT67046A patent/PT67046B/pt unknown
- 1977-09-22 FR FR7728627A patent/FR2365572A1/fr active Granted
- 1977-09-22 DE DE19772742725 patent/DE2742725A1/de not_active Withdrawn
- 1977-09-23 IT IT27901/77A patent/IT1143693B/it active
- 1977-09-23 LU LU78172A patent/LU78172A1/xx unknown
- 1977-09-26 SE SE7710762A patent/SE7710762L/xx unknown
- 1977-09-26 NO NO773296A patent/NO773296L/no unknown
- 1977-09-26 FI FI772829A patent/FI772829A/fi not_active Application Discontinuation
- 1977-09-26 GR GR54426A patent/GR63698B/el unknown
- 1977-09-27 JP JP11654177A patent/JPS5340797A/ja active Granted
- 1977-09-27 NL NL7710528A patent/NL7710528A/xx not_active Application Discontinuation
- 1977-09-27 PL PL20108277A patent/PL201082A1/xx unknown
- 1977-09-27 DD DD7700201224A patent/DD132587A5/xx unknown
Also Published As
Publication number | Publication date |
---|---|
LU78172A1 (e) | 1978-01-24 |
JPS5340797A (en) | 1978-04-13 |
NL7710528A (nl) | 1978-03-29 |
NO773296L (no) | 1978-03-29 |
NZ185169A (en) | 1979-10-25 |
DK406077A (da) | 1978-03-28 |
PL201082A1 (pl) | 1978-12-18 |
PT67046A (en) | 1977-10-01 |
FR2365572A1 (fr) | 1978-04-21 |
PT67046B (en) | 1979-02-16 |
DE2742725A1 (de) | 1978-03-30 |
AU2882977A (en) | 1979-03-22 |
ES462445A1 (es) | 1978-07-16 |
US4263311A (en) | 1981-04-21 |
IT1143693B (it) | 1986-10-22 |
SE7710762L (sv) | 1978-03-28 |
GR63698B (en) | 1979-11-30 |
FI772829A (fi) | 1978-03-28 |
DD132587A5 (de) | 1978-10-11 |
JPS6247875B2 (e) | 1987-10-09 |
Similar Documents
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |