FR2361393A1 - (2-azabicyclo (2.2.2)octane-2-yl) diphenylalcanones et derives, leur preparation et leurs utilisations therapeutiques, notamment comme anti-diarrheiques - Google Patents

(2-azabicyclo (2.2.2)octane-2-yl) diphenylalcanones et derives, leur preparation et leurs utilisations therapeutiques, notamment comme anti-diarrheiques

Info

Publication number
FR2361393A1
FR2361393A1 FR7720831A FR7720831A FR2361393A1 FR 2361393 A1 FR2361393 A1 FR 2361393A1 FR 7720831 A FR7720831 A FR 7720831A FR 7720831 A FR7720831 A FR 7720831A FR 2361393 A1 FR2361393 A1 FR 2361393A1
Authority
FR
France
Prior art keywords
derivatives
preparation
diphenylalcanones
azabicyclo
diarrhea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7720831A
Other languages
English (en)
Other versions
FR2361393B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2361393A1 publication Critical patent/FR2361393A1/fr
Application granted granted Critical
Publication of FR2361393B1 publication Critical patent/FR2361393B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

(2-AzabicycloØ2.2.2õoctane-2-yl)diphénylalcanones et dérivés, leur préparation et leurs utilisations thérapeutiques. Ces composés répondent à la formule générale
FR7720831A 1976-07-06 1977-07-06 (2-azabicyclo (2.2.2)octane-2-yl) diphenylalcanones et derives, leur preparation et leurs utilisations therapeutiques, notamment comme anti-diarrheiques Granted FR2361393A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/703,041 US4028364A (en) 1976-07-06 1976-07-06 2-Azabicyclo[2.2.2.]octan-2-yl-diphenyl-alkanones and related compounds

Publications (2)

Publication Number Publication Date
FR2361393A1 true FR2361393A1 (fr) 1978-03-10
FR2361393B1 FR2361393B1 (fr) 1980-10-17

Family

ID=24823720

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7720831A Granted FR2361393A1 (fr) 1976-07-06 1977-07-06 (2-azabicyclo (2.2.2)octane-2-yl) diphenylalcanones et derives, leur preparation et leurs utilisations therapeutiques, notamment comme anti-diarrheiques

Country Status (8)

Country Link
US (1) US4028364A (fr)
JP (1) JPS537682A (fr)
AU (1) AU507159B2 (fr)
BE (1) BE856485A (fr)
CA (1) CA1078389A (fr)
DE (1) DE2730312A1 (fr)
FR (1) FR2361393A1 (fr)
GB (1) GB1546528A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707911C1 (de) * 1987-03-12 1988-03-31 Texaco Ag Bicyclische Aminkatalysatoren
US5889019A (en) * 1995-11-29 1999-03-30 Eli Lilly And Company Heterocyclic compounds and their use
CA2441838A1 (fr) 2001-03-26 2002-10-03 Kotobuki Pharmaceutical Co., Ltd. Derives d'isoquinuclidine, methode de production et agents therapeutiques contenant ces derives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3318869A (en) * 1966-05-18 1967-05-09 Searle & Co Complex nitriles containing the azabicycloalkane structure
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3318869A (en) * 1966-05-18 1967-05-09 Searle & Co Complex nitriles containing the azabicycloalkane structure
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines

Also Published As

Publication number Publication date
JPS537682A (en) 1978-01-24
AU2675977A (en) 1979-01-11
AU507159B2 (en) 1980-02-07
FR2361393B1 (fr) 1980-10-17
DE2730312A1 (de) 1978-01-12
BE856485A (fr) 1978-01-05
US4028364A (en) 1977-06-07
CA1078389A (fr) 1980-05-27
GB1546528A (en) 1979-05-23

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Legal Events

Date Code Title Description
ST Notification of lapse