FR2357565A1 - Procede pour la production de derives de penam et cephem - Google Patents

Procede pour la production de derives de penam et cephem

Info

Publication number
FR2357565A1
FR2357565A1 FR7720915A FR7720915A FR2357565A1 FR 2357565 A1 FR2357565 A1 FR 2357565A1 FR 7720915 A FR7720915 A FR 7720915A FR 7720915 A FR7720915 A FR 7720915A FR 2357565 A1 FR2357565 A1 FR 2357565A1
Authority
FR
France
Prior art keywords
penam
cephem
derivatives
production
phosphite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7720915A
Other languages
English (en)
Other versions
FR2357565B3 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of FR2357565A1 publication Critical patent/FR2357565A1/fr
Application granted granted Critical
Publication of FR2357565B3 publication Critical patent/FR2357565B3/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Préparation de dérivés de penam et de cephem par réaction d'un phosphite-amide avec un halogénure d'acyle dans un solvant aprotique en présence d'un donneur de protons comme catalyseur. Le milieu réactionnel est additionné d'un acceptateur ou bloqueur de l'halogéno-phosphite qui se forme au cours de la réaction. Convient particulièrement à la préparation d'antibiotiques à partir des acides amine-6-pénicillanique et amino-7-céphalo-sporanique.
FR7720915A 1976-07-07 1977-07-07 Procede pour la production de derives de penam et cephem Granted FR2357565A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28346/76A GB1590433A (en) 1976-07-07 1976-07-07 Process for the production of penam and cephem derivatives

Publications (2)

Publication Number Publication Date
FR2357565A1 true FR2357565A1 (fr) 1978-02-03
FR2357565B3 FR2357565B3 (fr) 1980-05-16

Family

ID=10274231

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7720915A Granted FR2357565A1 (fr) 1976-07-07 1977-07-07 Procede pour la production de derives de penam et cephem

Country Status (12)

Country Link
JP (1) JPS537699A (fr)
AT (1) ATA490277A (fr)
DE (1) DE2730548A1 (fr)
DK (1) DK300277A (fr)
ES (1) ES460514A1 (fr)
FI (1) FI772114A (fr)
FR (1) FR2357565A1 (fr)
GB (1) GB1590433A (fr)
NL (1) NL7707523A (fr)
NO (1) NO772396L (fr)
PT (1) PT66774B (fr)
SE (1) SE7707824L (fr)

Also Published As

Publication number Publication date
NL7707523A (nl) 1978-01-10
PT66774B (en) 1978-12-15
GB1590433A (en) 1981-06-03
NO772396L (no) 1978-01-10
DK300277A (da) 1978-01-08
DE2730548A1 (de) 1978-01-12
FI772114A (fr) 1978-01-08
SE7707824L (sv) 1978-01-08
ES460514A1 (es) 1978-05-16
JPS537699A (en) 1978-01-24
ATA490277A (de) 1980-05-15
PT66774A (en) 1977-08-01
FR2357565B3 (fr) 1980-05-16

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Legal Events

Date Code Title Description
ST Notification of lapse