FR2356653A1 - Procede de desesterification d'esters d'antibiotiques de b-lactame - Google Patents
Procede de desesterification d'esters d'antibiotiques de b-lactameInfo
- Publication number
- FR2356653A1 FR2356653A1 FR7720118A FR7720118A FR2356653A1 FR 2356653 A1 FR2356653 A1 FR 2356653A1 FR 7720118 A FR7720118 A FR 7720118A FR 7720118 A FR7720118 A FR 7720118A FR 2356653 A1 FR2356653 A1 FR 2356653A1
- Authority
- FR
- France
- Prior art keywords
- desesterification
- esters
- lactam antibiotic
- deesterification
- penicillin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 3
- 229930182555 Penicillin Natural products 0.000 abstract 3
- 229940124587 cephalosporin Drugs 0.000 abstract 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 2
- -1 cephalosporin esters Chemical class 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 238000007257 deesterification reaction Methods 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000006004 trihaloethyl group Chemical group 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70185076A | 1976-07-01 | 1976-07-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2356653A1 true FR2356653A1 (fr) | 1978-01-27 |
| FR2356653B1 FR2356653B1 (enExample) | 1980-01-04 |
Family
ID=24818932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7720118A Granted FR2356653A1 (fr) | 1976-07-01 | 1977-06-30 | Procede de desesterification d'esters d'antibiotiques de b-lactame |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS535194A (enExample) |
| BE (1) | BE856288A (enExample) |
| DE (1) | DE2728578A1 (enExample) |
| ES (1) | ES460338A1 (enExample) |
| FR (1) | FR2356653A1 (enExample) |
| GB (1) | GB1582960A (enExample) |
| IL (1) | IL52144A (enExample) |
| NL (1) | NL7707302A (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1218646A (en) * | 1983-07-22 | 1987-03-03 | Jack W. Fisher | Deesterification to acids |
| DE3508258A1 (de) * | 1985-03-08 | 1986-09-18 | Bayer Ag, 5090 Leverkusen | Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln |
| DE3509618A1 (de) | 1985-03-16 | 1986-09-18 | Bayer Ag, 5090 Leverkusen | Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel |
| DE3803169A1 (de) | 1988-02-03 | 1989-08-17 | Bayer Ag | Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln |
| IN181697B (enExample) * | 1994-04-22 | 1998-09-05 | Ranbaxy Lab Ltd | |
| CN103588790A (zh) * | 2013-11-29 | 2014-02-19 | 中国科学院长春应用化学研究所 | 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法 |
-
1977
- 1977-05-22 IL IL52144A patent/IL52144A/xx unknown
- 1977-06-24 DE DE19772728578 patent/DE2728578A1/de not_active Withdrawn
- 1977-06-27 GB GB26788/77A patent/GB1582960A/en not_active Expired
- 1977-06-29 JP JP7847477A patent/JPS535194A/ja active Pending
- 1977-06-30 BE BE1008237A patent/BE856288A/xx unknown
- 1977-06-30 NL NL7707302A patent/NL7707302A/xx not_active Application Discontinuation
- 1977-06-30 FR FR7720118A patent/FR2356653A1/fr active Granted
- 1977-07-01 ES ES460338A patent/ES460338A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL52144A0 (en) | 1977-07-31 |
| ES460338A1 (es) | 1978-08-16 |
| NL7707302A (nl) | 1978-01-03 |
| JPS535194A (en) | 1978-01-18 |
| DE2728578A1 (de) | 1978-01-12 |
| IL52144A (en) | 1979-10-31 |
| FR2356653B1 (enExample) | 1980-01-04 |
| BE856288A (fr) | 1977-12-30 |
| GB1582960A (en) | 1981-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |