IE42329L - Cephalosporin derivatives. - Google Patents

Cephalosporin derivatives.

Info

Publication number
IE42329L
IE42329L IE750707A IE70775A IE42329L IE 42329 L IE42329 L IE 42329L IE 750707 A IE750707 A IE 750707A IE 70775 A IE70775 A IE 70775A IE 42329 L IE42329 L IE 42329L
Authority
IE
Ireland
Prior art keywords
esters
formula
image
cephalosporins
furoyl
Prior art date
Application number
IE750707A
Other versions
IE42329B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE42329L publication Critical patent/IE42329L/en
Publication of IE42329B1 publication Critical patent/IE42329B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Novel substituted 7-(alpha-ureidoacetamido)cephalosporins of the following formula <IMAGE> wherein R' = H or denotes methyl and R+R1 have the meaning defined in Claim 1, are prepared by reacting a compound of the formula II <IMAGE> with furoyl isocyanate or N-(2-furoyl)-N-methylcarbamoyl chloride. The free acids of the formula I, thus obtained, are also converted to their indanyl esters, phthalidyl esters and alkanoyloxymethyl esters having 1-4 C atoms in the alkyl part and, if desired, to their pharmaceutically acceptable salts. The said cephalosporins exhibit a broad spectrum of antibiotic action against gram-positive and gram-negative microorganisms. [GB1502342A]
IE707/75A 1974-04-01 1975-04-02 Cehalosporin antibiotics IE42329B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45649174A 1974-04-01 1974-04-01

Publications (2)

Publication Number Publication Date
IE42329L true IE42329L (en) 1975-10-01
IE42329B1 IE42329B1 (en) 1980-07-16

Family

ID=23812977

Family Applications (1)

Application Number Title Priority Date Filing Date
IE707/75A IE42329B1 (en) 1974-04-01 1975-04-02 Cehalosporin antibiotics

Country Status (24)

Country Link
JP (1) JPS50130784A (en)
AR (1) AR209924A1 (en)
AT (1) AT336790B (en)
AU (1) AU7963675A (en)
BE (1) BE827450A (en)
BG (1) BG27235A3 (en)
CA (1) CA1068260A (en)
CH (1) CH614716A5 (en)
CS (1) CS185229B2 (en)
DD (1) DD118882A5 (en)
DE (1) DE2513954A1 (en)
DK (1) DK130275A (en)
ES (1) ES436170A1 (en)
FR (1) FR2265393B1 (en)
GB (1) GB1502342A (en)
HU (1) HU171886B (en)
IE (1) IE42329B1 (en)
IL (1) IL46955A (en)
NL (1) NL7503882A (en)
PH (1) PH12409A (en)
PL (1) PL95575B1 (en)
SE (1) SE7503706L (en)
SU (1) SU584788A3 (en)
ZA (1) ZA752005B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4063019A (en) 1976-03-30 1977-12-13 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives

Also Published As

Publication number Publication date
AR209924A1 (en) 1977-06-15
DE2513954A1 (en) 1975-10-02
SE7503706L (en) 1975-10-02
FR2265393B1 (en) 1978-07-28
CH614716A5 (en) 1979-12-14
DD118882A5 (en) 1976-03-20
BG27235A3 (en) 1979-09-14
SU584788A3 (en) 1977-12-15
PH12409A (en) 1979-02-07
PL95575B1 (en) 1977-10-31
IL46955A0 (en) 1975-05-22
IL46955A (en) 1980-01-31
AT336790B (en) 1977-05-25
HU171886B (en) 1978-04-28
NL7503882A (en) 1975-10-03
ES436170A1 (en) 1977-02-01
IE42329B1 (en) 1980-07-16
FR2265393A1 (en) 1975-10-24
DK130275A (en) 1975-10-02
GB1502342A (en) 1978-03-01
CS185229B2 (en) 1978-09-15
ATA247575A (en) 1976-09-15
JPS50130784A (en) 1975-10-16
ZA752005B (en) 1976-11-24
AU7963675A (en) 1976-09-30
BE827450A (en) 1975-10-01
CA1068260A (en) 1979-12-18

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