FR2354991A1 - Procede de preparation d'acides 2-arylalcanoiques et de leurs sels et esters - Google Patents

Procede de preparation d'acides 2-arylalcanoiques et de leurs sels et esters

Info

Publication number
FR2354991A1
FR2354991A1 FR7718363A FR7718363A FR2354991A1 FR 2354991 A1 FR2354991 A1 FR 2354991A1 FR 7718363 A FR7718363 A FR 7718363A FR 7718363 A FR7718363 A FR 7718363A FR 2354991 A1 FR2354991 A1 FR 2354991A1
Authority
FR
France
Prior art keywords
preparation
arylalcanoic
esters
salts
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7718363A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2354991A1 publication Critical patent/FR2354991A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04—Monocyclic monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/72—Polycyclic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne un procédé de préparation de 2-aryl-alcanoates dont la portion alcanoate comprend 3, 5, 6 atomes de carbone. Ce procédé consiste à faire réagir un énol-éther d'une arylalkylcétone avec un sel de thallium trivalent, dans un solvant organique. L'ester intermédiaire est ensuite transformé en acide 2-aryl-alcanoïque correspondant ou en un sel. Application à la préparation d'un composé pharmaceutique anti-inflammatoire, analgésique ou anti-pyrétique ou d'un produit destiné à l'agriculture.
FR7718363A 1976-06-16 1977-06-15 Procede de preparation d'acides 2-arylalcanoiques et de leurs sels et esters Withdrawn FR2354991A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/696,720 US4107439A (en) 1976-06-16 1976-06-16 Process for preparing arylalkanoic acid derivatives

Publications (1)

Publication Number Publication Date
FR2354991A1 true FR2354991A1 (fr) 1978-01-13

Family

ID=24798264

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7718363A Withdrawn FR2354991A1 (fr) 1976-06-16 1977-06-15 Procede de preparation d'acides 2-arylalcanoiques et de leurs sels et esters

Country Status (5)

Country Link
US (1) US4107439A (fr)
JP (1) JPS52153932A (fr)
DE (1) DE2726561A1 (fr)
FR (1) FR2354991A1 (fr)
GB (1) GB1535690A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547578A1 (fr) * 1983-06-20 1984-12-21 Fabre Sa Pierre Acides (biphenylyl-4)-2 propioniques, nouveau procede de preparation et utilisation comme intermediaires de synthese

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172955A (en) * 1976-08-26 1979-10-30 Emery Industries, Inc. Thallium(III) reagents supported on montmorillonite clay minerals in oxythallation process
IE50898B1 (en) * 1980-02-26 1986-08-06 Blaschim Spa Process for preparing esters of 2-(6'-methoxy-2'-naphthyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphthyl)-propan-1-one
EP0052775B1 (fr) * 1980-11-21 1985-05-02 L. GIVAUDAN & CIE Société Anonyme Procédé pour la préparation d'aldéhydes et produits intermédiaires
EP0158255B1 (fr) * 1984-04-06 1989-01-04 ZAMBON S.p.A. Cétals optiquement actifs, procédés pour leur préparation et leur utilisation dans la synthèse d'acides alpha-arylalcanoiques
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4670586A (en) * 1984-09-12 1987-06-02 Nippon Chemicals Co., Ltd. Method for the production of α-aryl-alkanoic acid
JPS6363683A (ja) * 1986-09-04 1988-03-22 Shin Etsu Chem Co Ltd （フェニルジメチルカルビニル）シラン化合物の製造方法
IT1227537B (it) * 1987-07-28 1991-04-12 Zambon Spa Processo per la preparazione dell'acido s(+)-2-(6-metossi-2-naftil)- propionico
WO1992008686A1 (fr) * 1990-11-19 1992-05-29 Ethyl Corporation Procede servant a ameliorer les caracteristiques d'ecoulement d'ibuprofene cristallin
US5792886A (en) * 1997-01-08 1998-08-11 Albemarle Corporation Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof
US6096920A (en) * 1997-01-08 2000-08-01 Albemarle Corporation Preparation of carboxylic compounds and their derivatives
US6080888A (en) * 1997-01-08 2000-06-27 Albemarle Corporation Preparation of olefinic compounds and carboxylic derivatives thereof
IT1315212B1 (it) 1999-07-26 2003-02-03 Consiglio Nazionale Ricerche Impiego di ortoesteri per la sintesi di acidi chirali in processi diesterificazione irreversibili biocatalizzati.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547578A1 (fr) * 1983-06-20 1984-12-21 Fabre Sa Pierre Acides (biphenylyl-4)-2 propioniques, nouveau procede de preparation et utilisation comme intermediaires de synthese

Also Published As

Publication number Publication date
DE2726561A1 (de) 1977-12-29
JPS52153932A (en) 1977-12-21
US4107439A (en) 1978-08-15
GB1535690A (en) 1978-12-13

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Legal Events

Date Code Title Description
ST Notification of lapse