FR2352819A1 - Procede de preparation de sels alcalins de l'ampicilline, notamment du sel de sodium - Google Patents
Procede de preparation de sels alcalins de l'ampicilline, notamment du sel de sodiumInfo
- Publication number
- FR2352819A1 FR2352819A1 FR7716406A FR7716406A FR2352819A1 FR 2352819 A1 FR2352819 A1 FR 2352819A1 FR 7716406 A FR7716406 A FR 7716406A FR 7716406 A FR7716406 A FR 7716406A FR 2352819 A1 FR2352819 A1 FR 2352819A1
- Authority
- FR
- France
- Prior art keywords
- ampicillin
- salts
- sodium salt
- especially sodium
- preparing alkaline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical class C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- NOJNFULGOQGBKB-UHFFFAOYSA-M sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate Chemical compound [Na+].C1=NC(OCC)=CC=C1C(C=C1)=CC=C1CN1C2=CC=C(OCC=3N=CC(C)=CC=3)C=C2C(SC(C)(C)C)=C1CC(C)(C)C([O-])=O NOJNFULGOQGBKB-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2623835A DE2623835C2 (de) | 1976-05-28 | 1976-05-28 | Verfahren zur Herstellung von Natriumampicillin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2352819A1 true FR2352819A1 (fr) | 1977-12-23 |
| FR2352819B1 FR2352819B1 (enExample) | 1980-02-08 |
Family
ID=5979158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7716406A Granted FR2352819A1 (fr) | 1976-05-28 | 1977-05-27 | Procede de preparation de sels alcalins de l'ampicilline, notamment du sel de sodium |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4130558A (enExample) |
| JP (1) | JPS52151714A (enExample) |
| DE (1) | DE2623835C2 (enExample) |
| ES (1) | ES459223A1 (enExample) |
| FR (1) | FR2352819A1 (enExample) |
| GB (1) | GB1522470A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2502624A1 (fr) * | 1981-03-26 | 1982-10-01 | American Cyanamid Co | Composition comprenant une preparation lyophilisee d'un derive de penicilline et son procede de preparation |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT380258B (de) * | 1982-08-06 | 1986-05-12 | Biochemie Gmbh | Verfahren zur herstellung von natrium-ampicillin |
| JPS63174927A (ja) * | 1987-01-14 | 1988-07-19 | Tanabe Seiyaku Co Ltd | 抗菌性凍結乾燥製剤 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5119016B2 (enExample) * | 1972-03-10 | 1976-06-14 | ||
| GB1463563A (en) * | 1974-10-10 | 1977-02-02 | Beecham Group Ltd | Pharmaceutical compositions |
-
1976
- 1976-05-28 DE DE2623835A patent/DE2623835C2/de not_active Expired
-
1977
- 1977-05-18 US US05/797,928 patent/US4130558A/en not_active Expired - Lifetime
- 1977-05-27 ES ES459223A patent/ES459223A1/es not_active Expired
- 1977-05-27 GB GB22550/77A patent/GB1522470A/en not_active Expired
- 1977-05-27 JP JP6126577A patent/JPS52151714A/ja active Pending
- 1977-05-27 FR FR7716406A patent/FR2352819A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2502624A1 (fr) * | 1981-03-26 | 1982-10-01 | American Cyanamid Co | Composition comprenant une preparation lyophilisee d'un derive de penicilline et son procede de preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2352819B1 (enExample) | 1980-02-08 |
| ES459223A1 (es) | 1978-03-01 |
| GB1522470A (en) | 1978-08-23 |
| US4130558A (en) | 1978-12-19 |
| JPS52151714A (en) | 1977-12-16 |
| DE2623835C2 (de) | 1978-03-02 |
| DE2623835B1 (de) | 1977-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |