ES459223A1 - Procedimiento para la preparacion de sales alcalinos de am- picilina, especialmente de ampicilina sodica. - Google Patents
Procedimiento para la preparacion de sales alcalinos de am- picilina, especialmente de ampicilina sodica.Info
- Publication number
- ES459223A1 ES459223A1 ES459223A ES459223A ES459223A1 ES 459223 A1 ES459223 A1 ES 459223A1 ES 459223 A ES459223 A ES 459223A ES 459223 A ES459223 A ES 459223A ES 459223 A1 ES459223 A1 ES 459223A1
- Authority
- ES
- Spain
- Prior art keywords
- ampicillin
- alkali metal
- preparation
- metal salts
- filtrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052783 alkali metal Inorganic materials 0.000 title abstract 3
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical class C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 title abstract 3
- 229960000723 ampicillin Drugs 0.000 title abstract 3
- -1 alkali metal salts Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000706 filtrate Substances 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 230000008014 freezing Effects 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2623835A DE2623835C2 (de) | 1976-05-28 | 1976-05-28 | Verfahren zur Herstellung von Natriumampicillin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES459223A1 true ES459223A1 (es) | 1978-03-01 |
Family
ID=5979158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459223A Expired ES459223A1 (es) | 1976-05-28 | 1977-05-27 | Procedimiento para la preparacion de sales alcalinos de am- picilina, especialmente de ampicilina sodica. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4130558A (enExample) |
| JP (1) | JPS52151714A (enExample) |
| DE (1) | DE2623835C2 (enExample) |
| ES (1) | ES459223A1 (enExample) |
| FR (1) | FR2352819A1 (enExample) |
| GB (1) | GB1522470A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1209477A (en) * | 1981-03-26 | 1986-08-12 | Bruce E. Haeger | Composition of matter comprising a lyophilized preparation of a penicillin derivative |
| AT380258B (de) * | 1982-08-06 | 1986-05-12 | Biochemie Gmbh | Verfahren zur herstellung von natrium-ampicillin |
| JPS63174927A (ja) * | 1987-01-14 | 1988-07-19 | Tanabe Seiyaku Co Ltd | 抗菌性凍結乾燥製剤 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5119016B2 (enExample) * | 1972-03-10 | 1976-06-14 | ||
| GB1463563A (en) * | 1974-10-10 | 1977-02-02 | Beecham Group Ltd | Pharmaceutical compositions |
-
1976
- 1976-05-28 DE DE2623835A patent/DE2623835C2/de not_active Expired
-
1977
- 1977-05-18 US US05/797,928 patent/US4130558A/en not_active Expired - Lifetime
- 1977-05-27 ES ES459223A patent/ES459223A1/es not_active Expired
- 1977-05-27 GB GB22550/77A patent/GB1522470A/en not_active Expired
- 1977-05-27 JP JP6126577A patent/JPS52151714A/ja active Pending
- 1977-05-27 FR FR7716406A patent/FR2352819A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2352819B1 (enExample) | 1980-02-08 |
| GB1522470A (en) | 1978-08-23 |
| US4130558A (en) | 1978-12-19 |
| FR2352819A1 (fr) | 1977-12-23 |
| JPS52151714A (en) | 1977-12-16 |
| DE2623835C2 (de) | 1978-03-02 |
| DE2623835B1 (de) | 1977-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971103 |