FR2351112A1 - Derive de prostaglandine et medicament contenant ce derive - Google Patents
Derive de prostaglandine et medicament contenant ce deriveInfo
- Publication number
- FR2351112A1 FR2351112A1 FR7714201A FR7714201A FR2351112A1 FR 2351112 A1 FR2351112 A1 FR 2351112A1 FR 7714201 A FR7714201 A FR 7714201A FR 7714201 A FR7714201 A FR 7714201A FR 2351112 A1 FR2351112 A1 FR 2351112A1
- Authority
- FR
- France
- Prior art keywords
- cpds
- healing
- alpha
- derivs
- prostaglandin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- 230000035876 healing Effects 0.000 abstract 2
- 206010061459 Gastrointestinal ulcer Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/624,486 US3984400A (en) | 1975-10-21 | 1975-10-21 | 11-Desoxy-16-aryl-ω-tetranorprostaglandins |
FR7631769A FR2361871A1 (fr) | 1975-10-21 | 1976-10-21 | 11-desoxy-16-arylprostaglandines 13-acetyleniques |
FR7710593A FR2351111A1 (fr) | 1976-05-11 | 1977-04-07 | Methylacetals de 2-(2b-ethynyl-cyclopent-1a-yl) acetaldehydes et leur preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2351112A1 true FR2351112A1 (fr) | 1977-12-09 |
FR2351112B1 FR2351112B1 (enrdf_load_stackoverflow) | 1981-05-29 |
Family
ID=27250686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7714201A Granted FR2351112A1 (fr) | 1975-10-21 | 1977-05-10 | Derive de prostaglandine et medicament contenant ce derive |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2351112A1 (enrdf_load_stackoverflow) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2359125A1 (fr) * | 1976-02-04 | 1978-02-17 | Upjohn Co | Nouveaux derives de prostaglandine, leur procede de preparation et medicament les contenant |
FR2378777A1 (fr) * | 1977-01-31 | 1978-08-25 | Ono Pharmaceutical Co | Nouveaux analogues de prostaglandines |
FR2401141A1 (fr) * | 1977-03-07 | 1979-03-23 | Upjohn Co | Nouveaux derives halogenes de prostaglandines et medicaments les contenant |
FR2401921A1 (fr) * | 1977-07-28 | 1979-03-30 | Upjohn Co | Derives de prostaglandines |
EP0001270A1 (de) * | 1977-09-27 | 1979-04-04 | Hoechst Aktiengesellschaft | Neue Prostacyclin-Analoga, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Behandlung von Herzkreislauf-Krankheiten |
EP0005768A1 (en) * | 1978-05-17 | 1979-12-12 | The Wellcome Foundation Limited | Pharmaceutical formulations containing prostaglandin compounds and method for their preparation |
EP0013955A1 (de) * | 1979-01-25 | 1980-08-06 | Hoechst Aktiengesellschaft | Neue Analoga von Prostacyclin, deren Zwischenprodukte, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel |
EP0052204A1 (en) * | 1980-11-13 | 1982-05-26 | American Cyanamid Company | Prostacyclin analogs of the 1 series and related analogs |
FR2513639A1 (fr) * | 1981-09-25 | 1983-04-01 | Squibb & Sons Inc | Nouvelles prostacyclines dioxatricycliques utiles comme medicaments cardio-vasculaires et produits nouveaux utiles comme intermediaires pour leur synthese |
EP0084775A1 (de) * | 1982-01-21 | 1983-08-03 | MERCK PATENT GmbH | 13-Thia-Prostacycline |
WO2013024051A1 (en) * | 2011-08-12 | 2013-02-21 | Ascendis Pharma A/S | Sustained release composition of prostacyclin |
CN116621852A (zh) * | 2023-04-21 | 2023-08-22 | 大连理工大学 | 基于内过氧化物的抗凝剂及应用 |
-
1977
- 1977-05-10 FR FR7714201A patent/FR2351112A1/fr active Granted
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2359125A1 (fr) * | 1976-02-04 | 1978-02-17 | Upjohn Co | Nouveaux derives de prostaglandine, leur procede de preparation et medicament les contenant |
FR2362833A1 (fr) * | 1976-02-04 | 1978-03-24 | Upjohn Co | Nouveaux derives 5 de prostaglandine, leur procede de preparation et medicament les contenant |
FR2378777A1 (fr) * | 1977-01-31 | 1978-08-25 | Ono Pharmaceutical Co | Nouveaux analogues de prostaglandines |
FR2401141A1 (fr) * | 1977-03-07 | 1979-03-23 | Upjohn Co | Nouveaux derives halogenes de prostaglandines et medicaments les contenant |
FR2401139A2 (fr) * | 1977-03-07 | 1979-03-23 | Upjohn Co | Nouveaux derives d5 de prostaglandines, leur procede de preparation et medicaments les contenant |
FR2401921A1 (fr) * | 1977-07-28 | 1979-03-30 | Upjohn Co | Derives de prostaglandines |
FR2401920A1 (fr) * | 1977-07-28 | 1979-03-30 | Upjohn Co | Derives de prostaglandines |
EP0001270A1 (de) * | 1977-09-27 | 1979-04-04 | Hoechst Aktiengesellschaft | Neue Prostacyclin-Analoga, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Behandlung von Herzkreislauf-Krankheiten |
EP0005768A1 (en) * | 1978-05-17 | 1979-12-12 | The Wellcome Foundation Limited | Pharmaceutical formulations containing prostaglandin compounds and method for their preparation |
FR2425856A1 (fr) * | 1978-05-17 | 1979-12-14 | Wellcome Found | Medicament a base de prostaglandines |
EP0013955A1 (de) * | 1979-01-25 | 1980-08-06 | Hoechst Aktiengesellschaft | Neue Analoga von Prostacyclin, deren Zwischenprodukte, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel |
EP0052204A1 (en) * | 1980-11-13 | 1982-05-26 | American Cyanamid Company | Prostacyclin analogs of the 1 series and related analogs |
FR2513639A1 (fr) * | 1981-09-25 | 1983-04-01 | Squibb & Sons Inc | Nouvelles prostacyclines dioxatricycliques utiles comme medicaments cardio-vasculaires et produits nouveaux utiles comme intermediaires pour leur synthese |
EP0084775A1 (de) * | 1982-01-21 | 1983-08-03 | MERCK PATENT GmbH | 13-Thia-Prostacycline |
WO2013024051A1 (en) * | 2011-08-12 | 2013-02-21 | Ascendis Pharma A/S | Sustained release composition of prostacyclin |
US9872864B2 (en) | 2011-08-12 | 2018-01-23 | Ascendis Pharma A/S | Sustained release composition of prostacyclin |
CN116621852A (zh) * | 2023-04-21 | 2023-08-22 | 大连理工大学 | 基于内过氧化物的抗凝剂及应用 |
Also Published As
Publication number | Publication date |
---|---|
FR2351112B1 (enrdf_load_stackoverflow) | 1981-05-29 |
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