FR2346015A2 - O-acetoxybenzoyl-1-l-proline, son procede de preparation et son utilisation comme medicament - Google Patents
O-acetoxybenzoyl-1-l-proline, son procede de preparation et son utilisation comme medicamentInfo
- Publication number
- FR2346015A2 FR2346015A2 FR7517140A FR7517140A FR2346015A2 FR 2346015 A2 FR2346015 A2 FR 2346015A2 FR 7517140 A FR7517140 A FR 7517140A FR 7517140 A FR7517140 A FR 7517140A FR 2346015 A2 FR2346015 A2 FR 2346015A2
- Authority
- FR
- France
- Prior art keywords
- proline
- antithermics
- derivs
- analgesics
- salicylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 2
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 title abstract 2
- 229930182821 L-proline Natural products 0.000 title abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 title abstract 2
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 229960002429 proline Drugs 0.000 title abstract 2
- 230000001562 ulcerogenic effect Effects 0.000 title abstract 2
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 abstract 1
- 229960002591 hydroxyproline Drugs 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7517140A FR2346015A2 (fr) | 1975-06-02 | 1975-06-02 | O-acetoxybenzoyl-1-l-proline, son procede de preparation et son utilisation comme medicament |
ES445395A ES445395A1 (es) | 1975-06-02 | 1976-02-20 | Un procedimiento de preparacion de 1-o-acetoxibenzoil-4-hi- droxi-l'prolina y 1-o-acetoxibenzoil-l-prolina. |
DE19762607627 DE2607627A1 (de) | 1975-06-02 | 1976-02-25 | 1-0-acetoxybenzoyl-4-hydroxy-l-prolin sowie 1-0-acetoxybenzoyl-l-prolin, verfahren zu ihrer herstellung und ihre verwendung als medikament |
BE164782A BE839102A (fr) | 1975-06-02 | 1976-03-02 | 0-acetoxybenzoyl-1 hydroxy-4-l-pyroline et 0-acetoxybenzoyl-1-l-proline, leur procede de preparation et leur application en tant que substance active po ur medicament |
DD191822A DD124381A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-06-02 | 1976-03-12 | |
JP51055977A JPS6011693B2 (ja) | 1975-06-02 | 1976-05-14 | アセチルサリチル酸誘導体、その製造法ならびにそれを含有してなる解熱鎮痛剤および炎症抑制剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7517140A FR2346015A2 (fr) | 1975-06-02 | 1975-06-02 | O-acetoxybenzoyl-1-l-proline, son procede de preparation et son utilisation comme medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2346015A2 true FR2346015A2 (fr) | 1977-10-28 |
FR2346015B2 FR2346015B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-01-05 |
Family
ID=9155944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7517140A Granted FR2346015A2 (fr) | 1975-06-02 | 1975-06-02 | O-acetoxybenzoyl-1-l-proline, son procede de preparation et son utilisation comme medicament |
Country Status (6)
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4987042A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-12-26 | 1974-08-20 | ||
JPS6437398U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1987-08-28 | 1989-03-07 | ||
US20080102042A1 (en) * | 2004-10-28 | 2008-05-01 | Kyowa Hakko Kogyo Co., Ltd. | Oral Composition |
-
1975
- 1975-06-02 FR FR7517140A patent/FR2346015A2/fr active Granted
-
1976
- 1976-02-20 ES ES445395A patent/ES445395A1/es not_active Expired
- 1976-02-25 DE DE19762607627 patent/DE2607627A1/de not_active Withdrawn
- 1976-03-02 BE BE164782A patent/BE839102A/xx not_active IP Right Cessation
- 1976-03-12 DD DD191822A patent/DD124381A5/xx unknown
- 1976-05-14 JP JP51055977A patent/JPS6011693B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6011693B2 (ja) | 1985-03-27 |
ES445395A1 (es) | 1977-06-01 |
DE2607627A1 (de) | 1976-12-23 |
JPS525759A (en) | 1977-01-17 |
DD124381A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-02-16 |
FR2346015B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-01-05 |
BE839102A (fr) | 1976-07-01 |
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