FR2340736A1 - Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent - Google Patents
Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennentInfo
- Publication number
- FR2340736A1 FR2340736A1 FR7603603A FR7603603A FR2340736A1 FR 2340736 A1 FR2340736 A1 FR 2340736A1 FR 7603603 A FR7603603 A FR 7603603A FR 7603603 A FR7603603 A FR 7603603A FR 2340736 A1 FR2340736 A1 FR 2340736A1
- Authority
- FR
- France
- Prior art keywords
- antibilharziasis
- derivs
- dithiol
- agents
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002098 pyridazinyl group Chemical group 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- PCGDBWLKAYKBTN-UHFFFAOYSA-N 1,2-dithiole Chemical compound C1SSC=C1 PCGDBWLKAYKBTN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000973 chemotherapeutic effect Effects 0.000 abstract 1
- LLTXKLBTRRFJGZ-UHFFFAOYSA-N ethyl 3-oxo-3-pyridazin-3-ylpropanoate Chemical compound CCOC(=O)CC(=O)C1=CC=CN=N1 LLTXKLBTRRFJGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 abstract 1
- 125000002206 pyridazin-3-yl group Chemical group [H]C1=C([H])C([H])=C(*)N=N1 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
- 125000004527 pyrimidin-4-yl group Chemical group N1=CN=C(C=C1)* 0.000 abstract 1
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (30)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7603603A FR2340736A1 (fr) | 1976-02-10 | 1976-02-10 | Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent |
| EG60/77A EG13192A (en) | 1976-02-10 | 1977-02-01 | Nouveaux derives du dithiole-1,2 leur preparation et les compositions qui les contiennent |
| NLAANVRAGE7701103,A NL175823C (nl) | 1976-02-10 | 1977-02-02 | Werkwijze ter bereiding van een geneesmiddel met chemotherapeutische werking, aldus verkregen gevormd geneesmiddel, alsmede werkwijze ter bereiding van 1,2-dithiolderivaten, geschikt voor gebruik daarbij. |
| HU77RO00000913A HU172527B (hu) | 1976-02-10 | 1977-02-08 | Sposob poluchenija novykh proizvodnykh 1,2-ditiola |
| IL51402A IL51402A (en) | 1976-02-10 | 1977-02-08 | 5-pyridazinyl(pyrimidyl)-1,2-dithiole-3-thione derivatives,process for the preparation thereof and pharmaceutical compositions containing the same |
| AR266483A AR220892A1 (es) | 1976-02-10 | 1977-02-08 | Procedimiento para preparar(piridazinil-3)-5-ditiol-1,2 tiona-3 |
| MW3/77A MW377A1 (en) | 1976-02-10 | 1977-02-09 | New derivatives of 1,2-dithiole |
| ZM13/77A ZM1377A1 (en) | 1976-02-10 | 1977-02-09 | New derivatives of 1,2-dithiole |
| BE174798A BE851261A (fr) | 1976-02-10 | 1977-02-09 | Nouveaux derives du dithiole-1,2 |
| JP1347177A JPS52105181A (en) | 1976-02-10 | 1977-02-09 | Novel 1*22dithiol derivative |
| CA271,430A CA1075239A (en) | 1976-02-10 | 1977-02-09 | 1,2-dithiol derivatives, methods of preparation, compositions thereof |
| LU76727A LU76727A1 (enExample) | 1976-02-10 | 1977-02-09 | |
| ZA770744A ZA77744B (en) | 1976-02-10 | 1977-02-09 | New derivatives of 1,2-dithiole |
| DK55677A DK55677A (da) | 1976-02-10 | 1977-02-09 | Fremgangsmade til fremstilling af derivater af 1,2-dithiol |
| IE269/77A IE44462B1 (en) | 1976-02-10 | 1977-02-09 | New derivatives of 1,2 dithiole |
| CH158177A CH616161A5 (enExample) | 1976-02-10 | 1977-02-09 | |
| PH19437A PH12622A (en) | 1976-02-10 | 1977-02-09 | Derivatives of 1,2-dithiole |
| US05/766,967 US4104386A (en) | 1976-02-10 | 1977-02-09 | Derivatives of 1,2-dithiole and anti-bilharzia compositions thereof |
| SE7701459A SE427273B (sv) | 1976-02-10 | 1977-02-09 | Forfarande for framstellning av derivat av 1,2-ditiol-3-tion med verkan mot blodparasiter |
| GB5368/77A GB1520231A (en) | 1976-02-10 | 1977-02-09 | Derivatives of 1,2-dithiole |
| AU22139/77A AU505778B2 (en) | 1976-02-10 | 1977-02-09 | 1, 2-dithiole derivatives |
| PT66174A PT66174B (fr) | 1976-02-10 | 1977-02-09 | Procede pour la preparation de derives de ditiole-1,2 et de compositions qu'en contiennent |
| ES455789A ES455789A1 (es) | 1976-02-10 | 1977-02-10 | Procedimiento de preparacion de nuevos derivados del di- tiol-1,2. |
| OA56068A OA05566A (fr) | 1976-02-10 | 1977-02-10 | Nouveaux dérivés du dithiole-1,2 et leur procédé de préparation. |
| AT90177A AT349028B (de) | 1976-02-10 | 1977-02-10 | Verfahren zur herstellung von neuen 1,2- dithiolderivaten |
| DE2705582A DE2705582C3 (de) | 1976-02-10 | 1977-02-10 | 5-(Pyridazin-3-yl)-1,2-dithiol-3-thion, seine Herstellung und die es enthaltenden Zusammensetzungen |
| SU772450452A SU837324A3 (ru) | 1976-02-10 | 1977-02-10 | Способ получени производных1,2-диТиОлАНА |
| ES458019A ES458019A1 (es) | 1976-02-10 | 1977-04-21 | Procedimiento de preparacion de nuevos derivados del ditiol-1,2. |
| US05/852,458 US4145423A (en) | 1976-02-10 | 1977-11-17 | Pyrimidinyl-1,2-dithiole compounds and anti-bilharzia compositions thereof |
| AT71978A AT349029B (de) | 1976-02-10 | 1978-02-02 | Verfahren zur herstellung von neuen 1,2- dithiolderivaten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7603603A FR2340736A1 (fr) | 1976-02-10 | 1976-02-10 | Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2340736A1 true FR2340736A1 (fr) | 1977-09-09 |
| FR2340736B1 FR2340736B1 (enExample) | 1979-10-05 |
Family
ID=9168947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7603603A Granted FR2340736A1 (fr) | 1976-02-10 | 1976-02-10 | Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE851261A (enExample) |
| FR (1) | FR2340736A1 (enExample) |
| MW (1) | MW377A1 (enExample) |
| ZA (1) | ZA77744B (enExample) |
| ZM (1) | ZM1377A1 (enExample) |
-
1976
- 1976-02-10 FR FR7603603A patent/FR2340736A1/fr active Granted
-
1977
- 1977-02-09 BE BE174798A patent/BE851261A/xx not_active IP Right Cessation
- 1977-02-09 ZM ZM13/77A patent/ZM1377A1/xx unknown
- 1977-02-09 MW MW3/77A patent/MW377A1/xx unknown
- 1977-02-09 ZA ZA770744A patent/ZA77744B/xx unknown
Non-Patent Citations (1)
| Title |
|---|
| THE CHEMISTRY OF HETEROCYCLIC COMPOUNDS", VOL, 21 PREMIERE PARTIE, INTERSCIENCE 1966 : MULTI-SULFUR AND SULFUR AND OXYGEN FIVE AND SIX-MEMBERED HETEROCYCLES, PAGES 347-404) * |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA77744B (en) | 1977-12-28 |
| MW377A1 (en) | 1978-05-10 |
| ZM1377A1 (en) | 1978-07-21 |
| BE851261A (fr) | 1977-08-09 |
| FR2340736B1 (enExample) | 1979-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |