FR2334358B1 - - Google Patents

Info

Publication number
FR2334358B1
FR2334358B1 FR7538051A FR7538051A FR2334358B1 FR 2334358 B1 FR2334358 B1 FR 2334358B1 FR 7538051 A FR7538051 A FR 7538051A FR 7538051 A FR7538051 A FR 7538051A FR 2334358 B1 FR2334358 B1 FR 2334358B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7538051A
Other versions
FR2334358A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOGERAS
Original Assignee
SOGERAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOGERAS filed Critical SOGERAS
Priority to FR7538051A priority Critical patent/FR2334358A1/fr
Priority to NLAANVRAGE7603881,A priority patent/NL179975C/xx
Priority to NO761407A priority patent/NO761407L/no
Priority to US05/679,970 priority patent/US4064255A/en
Priority to DE2618152A priority patent/DE2618152C2/de
Priority to DK190276A priority patent/DK190276A/da
Priority to GB21778/76A priority patent/GB1561111A/en
Priority to BE171515A priority patent/BE847283A/fr
Priority to IL50881A priority patent/IL50881A/xx
Priority to MX76100516U priority patent/MX4253E/es
Priority to GR52353A priority patent/GR58260B/el
Priority to CH1545176A priority patent/CH620436A5/fr
Priority to JP51148256A priority patent/JPS5272829A/ja
Priority to ZA00767340A priority patent/ZA767340B/xx
Priority to AT910276A priority patent/AT354447B/de
Priority to AU20423/76A priority patent/AU508906B2/en
Priority to PT65950A priority patent/PT65950B/fr
Priority to LU76372A priority patent/LU76372A1/xx
Priority to AR265798A priority patent/AR212515A1/es
Priority to IT69941/76A priority patent/IT1125233B/it
Priority to HU76MA2838A priority patent/HU175629B/hu
Priority to ES454162A priority patent/ES454162A1/es
Priority to CA267,635A priority patent/CA1088939A/fr
Publication of FR2334358A1 publication Critical patent/FR2334358A1/fr
Application granted granted Critical
Publication of FR2334358B1 publication Critical patent/FR2334358B1/fr
Priority to CA343,566A priority patent/CA1098446A/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
    • C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D227/04—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR7538051A 1975-12-12 1975-12-12 Nouveaux medicaments derives de l'indole Granted FR2334358A1 (fr)

Priority Applications (24)

Application Number Priority Date Filing Date Title
FR7538051A FR2334358A1 (fr) 1975-12-12 1975-12-12 Nouveaux medicaments derives de l'indole
NLAANVRAGE7603881,A NL179975C (nl) 1975-12-12 1976-04-13 Werkwijze ter bereiding van een geneesmiddel.
NO761407A NO761407L (fr) 1975-12-12 1976-04-23
DE2618152A DE2618152C2 (de) 1975-12-12 1976-04-26 Arzneimittel auf der Grundlage von Indolderivaten
US05/679,970 US4064255A (en) 1975-12-12 1976-04-26 Compositions containing new indole derivatives and their use in pharmacology
DK190276A DK190276A (da) 1975-12-12 1976-04-28 Hidtil ukendte legemidler afledt af indol
GB21778/76A GB1561111A (en) 1975-12-12 1976-05-26 Medicaments
BE171515A BE847283A (fr) 1975-12-12 1976-10-14 Nouveaux medicaments derives de l'indole,
IL50881A IL50881A (en) 1975-12-12 1976-11-10 Psychotropic pharmaceutical compositions containing certain indole derivatives
MX76100516U MX4253E (es) 1975-12-12 1976-11-29 Procedimiento para preparar derivados del (piperidil-4-alquil) 3 indol
CH1545176A CH620436A5 (fr) 1975-12-12 1976-12-08
GR52353A GR58260B (en) 1975-12-12 1976-12-08 Nouveaux medicaments derives de l'indole
JP51148256A JPS5272829A (en) 1975-12-12 1976-12-09 Pharmaceutical composition
AT910276A AT354447B (de) 1975-12-12 1976-12-09 Verfahren zur herstellung von indolderivaten
AU20423/76A AU508906B2 (en) 1975-12-12 1976-12-09 Indole derivatives to treat malfunctions ofthe Serotoninergic system
ZA00767340A ZA767340B (en) 1975-12-12 1976-12-09 Improvements in medicaments
LU76372A LU76372A1 (fr) 1975-12-12 1976-12-10
AR265798A AR212515A1 (es) 1975-12-12 1976-12-10 Procedimiento para preparar nuevos derivados del(piperidil-4 alquil)-3 indol
PT65950A PT65950B (fr) 1975-12-12 1976-12-10 Nouveaux medicaments derives de l'indole
IT69941/76A IT1125233B (it) 1975-12-12 1976-12-10 Prodotti derivati dall indole
HU76MA2838A HU175629B (hu) 1975-12-12 1976-12-10 Sposob poluchenija proizvodnykh indola i farmacevticheskikh preparatov soderzhahhikh takie soedinenija
ES454162A ES454162A1 (es) 1975-12-12 1976-12-10 Un procedimiento para la preparacion de nuevos derivados delindol.
CA267,635A CA1088939A (fr) 1975-12-12 1976-12-10 Medicaments derives de l'indole
CA343,566A CA1098446A (fr) 1975-12-12 1979-11-30 Medicaments derives de l'indole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7538051A FR2334358A1 (fr) 1975-12-12 1975-12-12 Nouveaux medicaments derives de l'indole

Publications (2)

Publication Number Publication Date
FR2334358A1 FR2334358A1 (fr) 1977-07-08
FR2334358B1 true FR2334358B1 (fr) 1979-06-29

Family

ID=9163660

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7538051A Granted FR2334358A1 (fr) 1975-12-12 1975-12-12 Nouveaux medicaments derives de l'indole

Country Status (23)

Country Link
US (1) US4064255A (fr)
JP (1) JPS5272829A (fr)
AR (1) AR212515A1 (fr)
AT (1) AT354447B (fr)
AU (1) AU508906B2 (fr)
BE (1) BE847283A (fr)
CA (1) CA1088939A (fr)
CH (1) CH620436A5 (fr)
DE (1) DE2618152C2 (fr)
DK (1) DK190276A (fr)
ES (1) ES454162A1 (fr)
FR (1) FR2334358A1 (fr)
GB (1) GB1561111A (fr)
GR (1) GR58260B (fr)
HU (1) HU175629B (fr)
IL (1) IL50881A (fr)
IT (1) IT1125233B (fr)
LU (1) LU76372A1 (fr)
MX (1) MX4253E (fr)
NL (1) NL179975C (fr)
NO (1) NO761407L (fr)
PT (1) PT65950B (fr)
ZA (1) ZA767340B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208417A (en) * 1978-06-29 1980-06-17 Pharmindustrie Indole derivatives and their use as anxiolytics
FR2430769A1 (fr) * 1978-07-13 1980-02-08 Pharmindustrie Nouvelle composition analgesique contenant de l'((indolyl-3)-2 ethyl)-4 piperidine
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
DE3035403C2 (de) 1980-09-19 1982-08-26 Rütgerswerke AG, 6000 Frankfurt Verfahren zur Herstellung von 5-Chlorindol
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506310A1 (fr) 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
US4803218A (en) * 1982-09-29 1989-02-07 Mcneilab, Inc. 3-aminoalkyl-1H-indole-5-urea and amide derivatives
JPS6084281A (ja) * 1983-09-14 1985-05-13 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド類
JPS60142981A (ja) * 1983-12-28 1985-07-29 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド誘導体
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
TW197435B (fr) * 1990-11-22 1993-01-01 Takeda Pharm Industry Co Ltd
WO1992019595A1 (fr) * 1991-05-07 1992-11-12 Merck & Co., Inc. Antagonistes de recepteur de fibrinogene
TW263504B (fr) * 1991-10-03 1995-11-21 Pfizer
US5462934A (en) * 1992-03-09 1995-10-31 Takeda Chemical Industries Condensed heterocyclic ketone derivatives and their use
CA2092112A1 (fr) * 1992-03-23 1993-09-24 Nobuyoshi Iwata Derives d'indole et d'indazole, mode de preparation et utilisation pour le traitement et la prophylaxie des troubles cerebraux
US5358956A (en) * 1992-10-14 1994-10-25 Merck & Co., Inc. Fibrinogen receptor antagonists
US5340798A (en) * 1992-10-14 1994-08-23 Merck & Co., Inc. Fibrinogen receptor antagonists
DE69327536T2 (de) * 1992-10-14 2000-07-06 Merck & Co., Inc. Fibrinogenrezeptor-antagonisten
US5786373A (en) * 1992-10-14 1998-07-28 Merck & Co., Inc. Fibrinogen receptor antagonists
US5648368A (en) * 1992-12-01 1997-07-15 Merck & Co., Inc. Fibrinogen receptor antagonists
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
GB9310582D0 (en) * 1993-05-22 1993-07-07 Smithkline Beecham Plc Pharmaceuticals
US5397791A (en) * 1993-08-09 1995-03-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5789421A (en) * 1995-10-26 1998-08-04 Merck & Co., Inc. Fibrinogen receptor antagonist
US5780480A (en) * 1996-02-28 1998-07-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5889023A (en) * 1996-05-10 1999-03-30 Merck & Co., Inc. Fibrinogen receptor antagonist
CN1163224C (zh) 1998-09-30 2004-08-25 武田药品工业株式会社 改善膀胱排泄能力的药物
WO2005060968A1 (fr) 2003-12-11 2005-07-07 Sepracor Inc. Combinaison d'un sedatif et d'un modulateur des neurotransmetteurs, et methodes permettant d'ameliorer la qualite du sommeil et de traiter la depression
WO2005092885A1 (fr) * 2004-02-27 2005-10-06 Eli Lilly And Company Derives de 4-amino-piperidine utilises en tant qu'inhibiteurs de l'absorption des monoamines
US20080261955A1 (en) * 2004-10-01 2008-10-23 Timothy Dinan Use of Pharmaceutical Compositions of Lofepramine for the Treatment of Adhd, Cfs, Fm and Depression
JP3816093B1 (ja) * 2005-10-03 2006-08-30 マイルストーン株式会社 撮像レンズ
EP1842541A1 (fr) * 2006-03-29 2007-10-10 G.I.M.-Gesellschaft Für Innovative Medizin Gmbh Nfg Ohg Composé et extraits de plantes et leur utilisation
WO2014125084A1 (fr) 2013-02-14 2014-08-21 Technische Universität München Dérivés d'hydroxyindalpine et leur utilisation médicale

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3136770A (en) * 1960-04-01 1964-06-09 Neisler Lab Inc Indolyl substituted piperidines
GB925429A (en) * 1960-04-01 1963-05-08 Irwin Neisler & Co Indole derivatives
US3471499A (en) 1965-12-03 1969-10-07 American Home Prod 1,4-bis-(2-indol-3-yl-ethyl)piperazines
GB1237008A (en) * 1968-12-18 1971-06-30 Pfizer Ltd Novel indoline derivatives
GB1436771A (en) * 1973-02-16 1976-05-26 Labaz Indole derivatives and process for preparing the same

Also Published As

Publication number Publication date
IL50881A (en) 1979-11-30
CA1088939A (fr) 1980-11-04
US4064255A (en) 1977-12-20
DK190276A (da) 1977-06-13
IL50881A0 (en) 1977-01-31
JPS5272829A (en) 1977-06-17
AU508906B2 (en) 1980-04-03
NL179975B (nl) 1986-07-16
BE847283A (fr) 1977-04-14
AT354447B (de) 1979-01-10
CH620436A5 (fr) 1980-11-28
ATA910276A (de) 1979-06-15
GB1561111A (en) 1980-02-13
DE2618152C2 (de) 1983-05-05
JPS56435B2 (fr) 1981-01-08
ZA767340B (en) 1978-01-25
MX4253E (es) 1982-03-04
AR212515A1 (es) 1978-07-31
ES454162A1 (es) 1978-02-16
FR2334358A1 (fr) 1977-07-08
AU2042376A (en) 1978-06-15
DE2618152A1 (de) 1977-06-16
HU175629B (hu) 1980-09-28
LU76372A1 (fr) 1978-07-10
GR58260B (en) 1977-09-15
NO761407L (fr) 1977-06-14
PT65950B (fr) 1978-06-15
NL179975C (nl) 1986-12-16
IT1125233B (it) 1986-05-14
PT65950A (fr) 1977-01-01
NL7603881A (nl) 1977-06-14

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