FR2315274A1 - Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications - Google Patents

Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications

Info

Publication number
FR2315274A1
FR2315274A1 FR7520241A FR7520241A FR2315274A1 FR 2315274 A1 FR2315274 A1 FR 2315274A1 FR 7520241 A FR7520241 A FR 7520241A FR 7520241 A FR7520241 A FR 7520241A FR 2315274 A1 FR2315274 A1 FR 2315274A1
Authority
FR
France
Prior art keywords
thieno
pyridine
applications
preparation
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7520241A
Other languages
English (en)
French (fr)
Other versions
FR2315274B1 (enExample
Inventor
Jean-Pierre Maffrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor SARL filed Critical Parcor SARL
Priority to FR7520241A priority Critical patent/FR2315274A1/fr
Priority to CH612276A priority patent/CH596169A5/xx
Priority to IE1149/76A priority patent/IE43915B1/en
Priority to IL49702A priority patent/IL49702A/xx
Priority to GR50863A priority patent/GR60042B/el
Priority to US05/692,186 priority patent/US4075340A/en
Priority to ZA763270A priority patent/ZA763270B/xx
Priority to SU762367256A priority patent/SU628820A3/ru
Priority to YU1462/76A priority patent/YU39480B/xx
Priority to NLAANVRAGE7606574,A priority patent/NL183032C/xx
Priority to CA255,299A priority patent/CA1071635A/en
Priority to DK279976A priority patent/DK279976A/da
Priority to SE7607201A priority patent/SE421698B/xx
Priority to DE19762628045 priority patent/DE2628045A1/de
Priority to LU75230A priority patent/LU75230A1/xx
Priority to AT461776A priority patent/AT347950B/de
Priority to AR263737A priority patent/AR211777A1/es
Priority to PT65271A priority patent/PT65271B/pt
Priority to GB26591/76A priority patent/GB1492239A/en
Priority to BE168304A priority patent/BE843402A/xx
Priority to ES449191A priority patent/ES449191A1/es
Priority to MX76799U priority patent/MX3565E/es
Priority to DD193581A priority patent/DD125080A5/xx
Priority to HU76PA00001254A priority patent/HU172697B/hu
Priority to JP51075943A priority patent/JPS607633B2/ja
Priority to PL1976190741A priority patent/PL105962B1/pl
Priority to AU15375/76A priority patent/AU494432B2/en
Publication of FR2315274A1 publication Critical patent/FR2315274A1/fr
Application granted granted Critical
Publication of FR2315274B1 publication Critical patent/FR2315274B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FR7520241A 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications Granted FR2315274A1 (fr)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FR7520241A FR2315274A1 (fr) 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
CH612276A CH596169A5 (enExample) 1975-06-27 1976-05-17
IE1149/76A IE43915B1 (en) 1975-06-27 1976-05-31 Improvements in or relating to new thieno/2,3-c/pyridine derivatives
GR50863A GR60042B (en) 1975-06-27 1976-06-01 Preparation process of new thieno(2,3-c)pyridine derivatives
IL49702A IL49702A (en) 1975-06-27 1976-06-01 Thieno(2,3-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them
US05/692,186 US4075340A (en) 1975-06-27 1976-06-02 Thieno [2,3-C] pyridine derivatives and therapeutic composition containing same
ZA763270A ZA763270B (en) 1975-06-27 1976-06-02 New thieno(2,3-c)pyridine derivatives
SU762367256A SU628820A3 (ru) 1975-06-27 1976-06-14 Способ получени производных 4,5,6,7-тетрагидротиено(2,3-с) пиридина
YU1462/76A YU39480B (en) 1975-06-27 1976-06-15 Process for obtaining 4,5,6,7-tetrahydrotheno(2,3-c)pyridine derivatives
NLAANVRAGE7606574,A NL183032C (nl) 1975-06-27 1976-06-17 Werkwijze ter bereiding van farmaceutisch werkzame n-gesubstitueerde 4,5,6,7-tetrahydrothieno-pyridinederivaten, alsmede werkwijze ter bereiding van een farmaceutisch preparaat en farmaceutisch voorwerp.
CA255,299A CA1071635A (en) 1975-06-27 1976-06-21 Process for the preparation of new thieno (2, 3-c) pyridine derivatives
DK279976A DK279976A (da) 1975-06-27 1976-06-22 Fremgangsmade til fremstilling af thieno(2,3-c)pyridinderivater
DE19762628045 DE2628045A1 (de) 1975-06-27 1976-06-23 Thieno(2,3-c)pyridinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
SE7607201A SE421698B (sv) 1975-06-27 1976-06-23 Forfarande for framstellning av 4,5,6,7-tetrahydro-tieno (2,3-c) pyridinderivat
LU75230A LU75230A1 (enExample) 1975-06-27 1976-06-24
AR263737A AR211777A1 (es) 1975-06-27 1976-06-24 Procedimiento de preparacion de derivados de 4,5,6,7,tetrahidro-tieno(2,3-c)piridina
PT65271A PT65271B (fr) 1975-06-27 1976-06-24 Procede de preparation de nouveaux derives de la thieno (2,3-c) pyridine
AT461776A AT347950B (de) 1975-06-27 1976-06-24 Verfahren zur herstellung von neuen thieno (2,3-c) pyridinderivaten und deren salzen
BE168304A BE843402A (fr) 1975-06-27 1976-06-25 Derives de la thieno (2,3-c) pyridine, leur procede de preparation et composition therapeutique en contenant
ES449191A ES449191A1 (es) 1975-06-27 1976-06-25 Un procedimiento de preparacion de derivados de 4,5,6,7-te- trahidro-tieno-(2,3-c)-piridina.
MX76799U MX3565E (es) 1975-06-27 1976-06-25 Procedimiento de preparacion de derivados de la tieno(2,3-c)-piridina
DD193581A DD125080A5 (enExample) 1975-06-27 1976-06-25
GB26591/76A GB1492239A (en) 1975-06-27 1976-06-25 Thieno(2,3-c)pyridine derivatives
HU76PA00001254A HU172697B (hu) 1975-06-27 1976-06-25 Sposob poluchenija proizvodnykh tieno-skobka-2,3-c-skobka zakryta-piridina
JP51075943A JPS607633B2 (ja) 1975-06-27 1976-06-26 ピリジン誘導体及びその製法
PL1976190741A PL105962B1 (pl) 1975-06-27 1976-06-26 Sposob wytwarzania nowych pochodnych tieno/2,3-c/pirydyny
AU15375/76A AU494432B2 (en) 1975-06-27 1976-06-28 Thieno [2,3-c] pyridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7520241A FR2315274A1 (fr) 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications

Publications (2)

Publication Number Publication Date
FR2315274A1 true FR2315274A1 (fr) 1977-01-21
FR2315274B1 FR2315274B1 (enExample) 1979-08-10

Family

ID=9157178

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7520241A Granted FR2315274A1 (fr) 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications

Country Status (26)

Country Link
US (1) US4075340A (enExample)
JP (1) JPS607633B2 (enExample)
AR (1) AR211777A1 (enExample)
AT (1) AT347950B (enExample)
BE (1) BE843402A (enExample)
CA (1) CA1071635A (enExample)
CH (1) CH596169A5 (enExample)
DD (1) DD125080A5 (enExample)
DE (1) DE2628045A1 (enExample)
DK (1) DK279976A (enExample)
ES (1) ES449191A1 (enExample)
FR (1) FR2315274A1 (enExample)
GB (1) GB1492239A (enExample)
GR (1) GR60042B (enExample)
HU (1) HU172697B (enExample)
IE (1) IE43915B1 (enExample)
IL (1) IL49702A (enExample)
LU (1) LU75230A1 (enExample)
MX (1) MX3565E (enExample)
NL (1) NL183032C (enExample)
PL (1) PL105962B1 (enExample)
PT (1) PT65271B (enExample)
SE (1) SE421698B (enExample)
SU (1) SU628820A3 (enExample)
YU (1) YU39480B (enExample)
ZA (1) ZA763270B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2405948A1 (fr) * 1977-10-15 1979-05-11 Boehringer Sohn Ingelheim Nouvelles 4-phenyl-thieno-(2,3-c)- piperidines, procedes pour leur preparation et compositions pharmaceutiques les renfermant

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2395271A1 (fr) * 1977-06-21 1979-01-19 Parcor Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines
US4749692A (en) * 1977-06-22 1988-06-07 Sanofi, S.A. Therapeutic compositions having anti-thrombotic and anti-blood-platelet-aggregating activity
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
FR2397417A1 (fr) * 1977-07-12 1979-02-09 Parcor Procede de preparation de derives de la thienopyridine
US4321266A (en) * 1980-10-06 1982-03-23 Sanofi 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine
FR2508453A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus
US4547514A (en) * 1983-12-05 1985-10-15 A. H. Robins Company, Incorporated Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity
DE3736664A1 (de) * 1987-10-29 1989-05-11 Boehringer Ingelheim Kg Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
AU4698299A (en) 1998-06-30 2000-01-17 Du Pont Pharmaceuticals Company 5-HT7 receptor antagonists
AU5154699A (en) * 1998-09-02 2000-03-27 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-c)pyridine derivatives
US6090797A (en) * 1998-09-02 2000-07-18 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-C)pyridine derivatives
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
JP2005522457A (ja) * 2002-02-26 2005-07-28 ノース ショア−ロング アイランド ジューイッシュ リサーチ インスティチュート 脳ムスカリン性レセプターの刺激による炎症性サイトカイン産生の阻害
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
JP2007530586A (ja) 2004-03-25 2007-11-01 ザ ファインスタイン インスティテュート フォー メディカル リサーチ 神経性止血法
CA2593079C (en) 2004-12-27 2014-08-19 North Shore-Long Island Jewish Research Institute Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
WO2009029614A1 (en) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US8412338B2 (en) 2008-11-18 2013-04-02 Setpoint Medical Corporation Devices and methods for optimizing electrode placement for anti-inflamatory stimulation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
EP2440284B1 (en) 2009-06-09 2018-09-12 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
WO2011079309A2 (en) 2009-12-23 2011-06-30 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
CN103619405B (zh) 2011-05-09 2015-11-25 赛博恩特医疗器械公司 用于治疗慢性炎症的胆碱能抗炎通路的单个脉冲激活
CN104364257B (zh) 2012-03-23 2017-03-01 纪念斯隆-凯特琳癌症中心 5‑酰基‑6,7‑二氢噻吩并[3,2‑c]吡啶类化合物对胰腺及相关癌症的治疗作用
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
WO2016018701A1 (en) 2014-07-28 2016-02-04 Merck Sharp & Dohme Corp. FACTOR XIa INHIBITORS
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
WO2017127756A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Control of vagal stimulation
EP3405255A4 (en) 2016-01-20 2019-10-16 Setpoint Medical Corporation IMPLANTABLE MICROSTIMULATORS AND INDUCTIVE CHARGING SYSTEMS
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
EP3668402B1 (en) 2017-08-14 2024-07-31 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
EP3952982B1 (en) 2019-04-12 2024-03-27 Setpoint Medical Corporation Vagus nerve stimulation system to treat neurodegenerative disorders
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
US12444497B2 (en) 2021-05-17 2025-10-14 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948A1 (enExample) * 1973-02-01 1974-08-30 Centre Etd Ind Pharma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948A1 (enExample) * 1973-02-01 1974-08-30 Centre Etd Ind Pharma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2405948A1 (fr) * 1977-10-15 1979-05-11 Boehringer Sohn Ingelheim Nouvelles 4-phenyl-thieno-(2,3-c)- piperidines, procedes pour leur preparation et compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
NL7606574A (nl) 1976-12-29
GB1492239A (en) 1977-11-16
HU172697B (hu) 1978-11-28
FR2315274B1 (enExample) 1979-08-10
NL183032B (nl) 1988-02-01
IE43915B1 (en) 1981-07-01
MX3565E (es) 1981-03-13
ZA763270B (en) 1977-05-25
IL49702A0 (en) 1976-08-31
IL49702A (en) 1979-01-31
PT65271A (fr) 1976-07-01
PL105962B1 (pl) 1979-11-30
AT347950B (de) 1979-01-25
SE421698B (sv) 1982-01-25
YU146276A (en) 1982-05-31
YU39480B (en) 1984-12-31
JPS607633B2 (ja) 1985-02-26
CH596169A5 (enExample) 1978-02-28
AR211777A1 (es) 1978-03-15
IE43915L (en) 1976-12-27
AU1537576A (en) 1978-01-05
DD125080A5 (enExample) 1977-03-30
DE2628045A1 (de) 1977-01-20
CA1071635A (en) 1980-02-12
NL183032C (nl) 1988-07-01
LU75230A1 (enExample) 1977-02-18
GR60042B (en) 1978-04-01
SE7607201L (sv) 1976-12-28
SU628820A3 (ru) 1978-10-15
US4075340A (en) 1978-02-21
JPS525793A (en) 1977-01-17
BE843402A (fr) 1976-12-27
ES449191A1 (es) 1977-12-01
DK279976A (da) 1976-12-28
ATA461776A (de) 1978-06-15
PT65271B (fr) 1977-12-10

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