FR2311776B1 - - Google Patents

Info

Publication number
FR2311776B1
FR2311776B1 FR7516088A FR7516088A FR2311776B1 FR 2311776 B1 FR2311776 B1 FR 2311776B1 FR 7516088 A FR7516088 A FR 7516088A FR 7516088 A FR7516088 A FR 7516088A FR 2311776 B1 FR2311776 B1 FR 2311776B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7516088A
Other languages
French (fr)
Other versions
FR2311776A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOGERAS
Original Assignee
SOGERAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOGERAS filed Critical SOGERAS
Priority to FR7516088A priority Critical patent/FR2311776A1/fr
Priority to CH627176A priority patent/CH602663A5/xx
Priority to NL7605319A priority patent/NL7605319A/xx
Priority to US05/687,972 priority patent/US4051244A/en
Priority to DE19762622639 priority patent/DE2622639A1/de
Priority to CA253,151A priority patent/CA1068270A/fr
Priority to IT6824376A priority patent/IT1070500B/it
Priority to PT6512276A priority patent/PT65122B/pt
Priority to LU75002A priority patent/LU75002A1/xx
Priority to GB2100276A priority patent/GB1554227A/en
Priority to ES448168A priority patent/ES448168A1/es
Priority to MX10034476U priority patent/MX3527E/es
Publication of FR2311776A1 publication Critical patent/FR2311776A1/fr
Application granted granted Critical
Publication of FR2311776B1 publication Critical patent/FR2311776B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7516088A 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation Granted FR2311776A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7516088A FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation
CH627176A CH602663A5 (OSRAM) 1975-05-23 1976-05-19
NL7605319A NL7605319A (nl) 1975-05-23 1976-05-19 Werkwijze ter bereiding van een geneesmiddel, zo gevormd geneesmiddel en werkwijze ter bereiding van geschikte geneeskrachtige verbindingen.
DE19762622639 DE2622639A1 (de) 1975-05-23 1976-05-20 2,4-diamino-5-brom-6-chlor-pyrimidinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
US05/687,972 US4051244A (en) 1975-05-23 1976-05-20 2,4-diamino 5-bromo 6-chloro pyrimidines, process for their preparation and use as pharmaceuticals
IT6824376A IT1070500B (it) 1975-05-23 1976-05-21 Diamino 2..4 bromo 5 cloro 6 pirimidine utilizzabili come prodotti come tali e procedimento per la loro proparazione
CA253,151A CA1068270A (fr) 1975-05-23 1976-05-21 Diamino-2,4-bromo-5 chloro-6 pyrimidines utilisables comme medicaments et procede pour leur preparation
PT6512276A PT65122B (fr) 1975-05-23 1976-05-21 Diamino-2,4 bromo-5 chloro-6 pyrimidines utilisables commemedicaments et procede pour preparation
LU75002A LU75002A1 (OSRAM) 1975-05-23 1976-05-21
GB2100276A GB1554227A (en) 1975-05-23 1976-05-21 Pyrimidines and in their preparation
ES448168A ES448168A1 (es) 1975-05-23 1976-05-21 Un procedimiento para la preparacion de nuevos derivados de pirimidina.
MX10034476U MX3527E (es) 1975-05-23 1976-05-31 Procedimiento para la preparacion de 2,4,diamina-5-bromo-6-cloro-pirimidinas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7516088A FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation

Publications (2)

Publication Number Publication Date
FR2311776A1 FR2311776A1 (fr) 1976-12-17
FR2311776B1 true FR2311776B1 (OSRAM) 1978-09-08

Family

ID=9155581

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7516088A Granted FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation

Country Status (2)

Country Link
US (1) US4051244A (OSRAM)
FR (1) FR2311776A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386199B (de) * 1981-04-07 1988-07-11 Pharmindustrie Verfahren zur herstellung von neuen 2-piperazinopyrimidinen

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417507A2 (fr) * 1977-07-28 1979-09-14 Ugine Kuhlmann Diamino-2,4 (ou -4,6) methylthio-5 pyrimidines herbicides
DE3417264A1 (de) * 1984-05-10 1985-11-14 Bayer Ag, 5090 Leverkusen Neue 2,4-diamino-6-halogen-5-alkylthio-pyrimidine
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
TWI417095B (zh) * 2006-03-15 2013-12-01 Janssen Pharmaceuticals Inc １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) * 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
HUP0700269A2 (en) * 2007-04-11 2009-04-28 Richter Gedeon Nyrt Pyrimidinyl-piperazines useful as d3/d2 receptor ligands, pharmaceutical compositions containing them and their use
KR20100065191A (ko) 2007-09-14 2010-06-15 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 １,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온
KR20100080597A (ko) * 2007-09-14 2010-07-09 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 １,３-이치환된-４-페닐-1ｈ-피리딘-2-온
CA2696948C (en) * 2007-09-14 2013-04-30 Jose Maria Cid-Nunez 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-ones
EP2220083B1 (en) * 2007-11-14 2017-07-19 Janssen Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CA2735764C (en) 2008-09-02 2016-06-14 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
AU2009304293B2 (en) 2008-10-16 2012-04-26 Addex Pharma S.A. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
BRPI0921333A2 (pt) 2008-11-28 2015-12-29 Addex Pharmaceuticals Sa derivados de indol e benzoxazina como moduladores de receptores de glutamato metabotrópicos
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
NZ596078A (en) 2009-05-12 2013-06-28 Janssen Pharmaceuticals Inc 1,2,4-TRIAZOLO [4,3-a] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
EA020671B1 (ru) 2009-05-12 2014-12-30 Янссен Фармасьютикалз, Инк. ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2
CA2815002C (en) 2010-11-08 2019-10-22 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN103298810B (zh) 2010-11-08 2016-03-16 杨森制药公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
EP2643320B1 (en) 2010-11-08 2015-03-04 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
KR102414246B1 (ko) 2014-01-21 2022-06-27 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
LT3431106T (lt) 2014-01-21 2021-02-10 Janssen Pharmaceutica Nv Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
CH512187A (de) * 1969-02-14 1971-09-15 Sandoz Ag Herbizides Mittel
US3892554A (en) * 1969-02-14 1975-07-01 Sandoz Ltd 2-Amino-4-isopropylamino-6-chloro-pyrimidine in maize, wheat, potatoes, onions and leeks
DE2263052A1 (de) * 1972-12-22 1974-07-04 Wacker Chemie Gmbh Neue pyrimidine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386199B (de) * 1981-04-07 1988-07-11 Pharmindustrie Verfahren zur herstellung von neuen 2-piperazinopyrimidinen

Also Published As

Publication number Publication date
US4051244A (en) 1977-09-27
FR2311776A1 (fr) 1976-12-17

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Legal Events

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