FR2311776B1 - - Google Patents

Info

Publication number
FR2311776B1
FR2311776B1 FR7516088A FR7516088A FR2311776B1 FR 2311776 B1 FR2311776 B1 FR 2311776B1 FR 7516088 A FR7516088 A FR 7516088A FR 7516088 A FR7516088 A FR 7516088A FR 2311776 B1 FR2311776 B1 FR 2311776B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7516088A
Other versions
FR2311776A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOGERAS
Original Assignee
SOGERAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOGERAS filed Critical SOGERAS
Priority to FR7516088A priority Critical patent/FR2311776A1/fr
Priority to CH627176A priority patent/CH602663A5/xx
Priority to NL7605319A priority patent/NL7605319A/xx
Priority to US05/687,972 priority patent/US4051244A/en
Priority to DE19762622639 priority patent/DE2622639A1/de
Priority to ES448168A priority patent/ES448168A1/es
Priority to CA253,151A priority patent/CA1068270A/fr
Priority to IT6824376A priority patent/IT1070500B/it
Priority to LU75002A priority patent/LU75002A1/xx
Priority to PT6512276A priority patent/PT65122B/fr
Priority to GB2100276A priority patent/GB1554227A/en
Priority to MX10034476U priority patent/MX3527E/es
Publication of FR2311776A1 publication Critical patent/FR2311776A1/fr
Application granted granted Critical
Publication of FR2311776B1 publication Critical patent/FR2311776B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7516088A 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation Granted FR2311776A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7516088A FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation
CH627176A CH602663A5 (fr) 1975-05-23 1976-05-19
NL7605319A NL7605319A (nl) 1975-05-23 1976-05-19 Werkwijze ter bereiding van een geneesmiddel, zo gevormd geneesmiddel en werkwijze ter bereiding van geschikte geneeskrachtige verbindingen.
DE19762622639 DE2622639A1 (de) 1975-05-23 1976-05-20 2,4-diamino-5-brom-6-chlor-pyrimidinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
US05/687,972 US4051244A (en) 1975-05-23 1976-05-20 2,4-diamino 5-bromo 6-chloro pyrimidines, process for their preparation and use as pharmaceuticals
CA253,151A CA1068270A (fr) 1975-05-23 1976-05-21 Diamino-2,4-bromo-5 chloro-6 pyrimidines utilisables comme medicaments et procede pour leur preparation
ES448168A ES448168A1 (es) 1975-05-23 1976-05-21 Un procedimiento para la preparacion de nuevos derivados de pirimidina.
IT6824376A IT1070500B (it) 1975-05-23 1976-05-21 Diamino 2..4 bromo 5 cloro 6 pirimidine utilizzabili come prodotti come tali e procedimento per la loro proparazione
LU75002A LU75002A1 (fr) 1975-05-23 1976-05-21
PT6512276A PT65122B (fr) 1975-05-23 1976-05-21 Diamino-2,4 bromo-5 chloro-6 pyrimidines utilisables commemedicaments et procede pour preparation
GB2100276A GB1554227A (en) 1975-05-23 1976-05-21 Pyrimidines and in their preparation
MX10034476U MX3527E (es) 1975-05-23 1976-05-31 Procedimiento para la preparacion de 2,4,diamina-5-bromo-6-cloro-pirimidinas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7516088A FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation

Publications (2)

Publication Number Publication Date
FR2311776A1 FR2311776A1 (fr) 1976-12-17
FR2311776B1 true FR2311776B1 (fr) 1978-09-08

Family

ID=9155581

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7516088A Granted FR2311776A1 (fr) 1975-05-23 1975-05-23 Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation

Country Status (2)

Country Link
US (1) US4051244A (fr)
FR (1) FR2311776A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386199B (de) * 1981-04-07 1988-07-11 Pharmindustrie Verfahren zur herstellung von neuen 2-piperazinopyrimidinen

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417507A2 (fr) * 1977-07-28 1979-09-14 Ugine Kuhlmann Diamino-2,4 (ou -4,6) methylthio-5 pyrimidines herbicides
DE3417264A1 (de) * 1984-05-10 1985-11-14 Bayer Ag, 5090 Leverkusen Neue 2,4-diamino-6-halogen-5-alkylthio-pyrimidine
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200845978A (en) * 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
HUP0700269A2 (en) 2007-04-11 2009-04-28 Richter Gedeon Nyrt Pyrimidinyl-piperazines useful as d3/d2 receptor ligands, pharmaceutical compositions containing them and their use
AU2008297876B2 (en) 2007-09-14 2011-07-07 Addex Pharma S.A. 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
BRPI0816767B8 (pt) * 2007-09-14 2021-05-25 Addex Pharmaceuticals Sa composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos
CN101801930B (zh) * 2007-09-14 2013-01-30 奥梅-杨森制药有限公司 1,3-二取代的-4-苯基-1h-吡啶-2-酮
ES2637794T3 (es) * 2007-11-14 2017-10-17 Janssen Pharmaceuticals, Inc. Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2
AU2009289784B2 (en) 2008-09-02 2012-03-22 Addex Pharma S.A. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
WO2010043396A1 (fr) 2008-10-16 2010-04-22 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Dérivés d’indole et de benzomorpholine en tant que modulateurs des récepteurs métabotropiques du glutamate
WO2010060589A1 (fr) 2008-11-28 2010-06-03 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Dérivés d'indole et de benzoxazine comme modulateurs des récepteurs métabotropiques au glutamate
MY161325A (en) 2009-05-12 2017-04-14 Janssen Pharmaceuticals Inc 1, 2, 4-triazolo[4,3-a]pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders
US8946205B2 (en) 2009-05-12 2015-02-03 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
CN103261195B (zh) 2010-11-08 2015-09-02 杨森制药公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
AU2011328203B2 (en) 2010-11-08 2015-03-19 Janssen Pharmaceuticals, Inc. 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
PL2649069T3 (pl) 2010-11-08 2016-01-29 Janssen Pharmaceuticals Inc Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
KR102461134B1 (ko) 2014-01-21 2022-10-28 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
UA121965C2 (uk) 2014-01-21 2020-08-25 Янссен Фармацевтика Нв Комбінації, які містять позитивні алостеричні модулятори або ортостеричні агоністи метаботропного глутаматергічного рецептора 2 підтипу, та їх застосування

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
US3892554A (en) * 1969-02-14 1975-07-01 Sandoz Ltd 2-Amino-4-isopropylamino-6-chloro-pyrimidine in maize, wheat, potatoes, onions and leeks
CH512187A (de) * 1969-02-14 1971-09-15 Sandoz Ag Herbizides Mittel
DE2263052A1 (de) * 1972-12-22 1974-07-04 Wacker Chemie Gmbh Neue pyrimidine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386199B (de) * 1981-04-07 1988-07-11 Pharmindustrie Verfahren zur herstellung von neuen 2-piperazinopyrimidinen

Also Published As

Publication number Publication date
FR2311776A1 (fr) 1976-12-17
US4051244A (en) 1977-09-27

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Legal Events

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TP Transmission of property
ST Notification of lapse