FR2300090A1 - Procede de preparation de derives de la thienopyridine - Google Patents
Procede de preparation de derives de la thienopyridineInfo
- Publication number
- FR2300090A1 FR2300090A1 FR7503968A FR7503968A FR2300090A1 FR 2300090 A1 FR2300090 A1 FR 2300090A1 FR 7503968 A FR7503968 A FR 7503968A FR 7503968 A FR7503968 A FR 7503968A FR 2300090 A1 FR2300090 A1 FR 2300090A1
- Authority
- FR
- France
- Prior art keywords
- formaldehyde
- prepn
- thiophenes
- cyclizing
- thieno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 title abstract 6
- WJFYLCXWEXZNHU-UHFFFAOYSA-N 2,3,3a,4-tetrahydrothieno[3,2-b]pyridine Chemical compound N1C=CC=C2SCCC21 WJFYLCXWEXZNHU-UHFFFAOYSA-N 0.000 title 1
- HVLUYXIJZLDNIS-UHFFFAOYSA-N 2-thiophen-2-ylethanamine Chemical class NCCC1=CC=CS1 HVLUYXIJZLDNIS-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- DBDCNCCRPKTRSD-UHFFFAOYSA-N thieno[3,2-b]pyridine Chemical compound C1=CC=C2SC=CC2=N1 DBDCNCCRPKTRSD-UHFFFAOYSA-N 0.000 abstract 1
- 229940125670 thienopyridine Drugs 0.000 abstract 1
- 239000002175 thienopyridine Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7503968A FR2300090A1 (fr) | 1975-02-07 | 1975-02-07 | Procede de preparation de derives de la thienopyridine |
| GR49763A GR58595B (en) | 1975-02-07 | 1976-01-13 | Preparation method of thieno-pyridines derivatives |
| CH97876A CH599217A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-02-07 | 1976-01-27 | |
| AR262031A AR211532A1 (es) | 1975-02-07 | 1976-01-27 | Un procedimiento de preparacion de derivados de la tienopiridina |
| ES444644A ES444644A1 (es) | 1975-02-07 | 1976-01-27 | Un procedimiento de preparacion de derivados de la tienopi- ridina. |
| IL48926A IL48926A (en) | 1975-02-07 | 1976-01-28 | Preparation of 4,5,6,7-tetrahydrothieno(3,2-c)pyridine derivatives |
| ZA760474A ZA76474B (en) | 1975-02-07 | 1976-01-28 | Process for the preparation of thienopyridine derivatives |
| NLAANVRAGE7600998,A NL181432C (nl) | 1975-02-07 | 1976-01-30 | Werkwijze ter bereiding van 4,5,6,7-tetrahydrothieno(3,2-c)pyridinederivaten. |
| SU762316003A SU640665A3 (ru) | 1975-02-07 | 1976-02-02 | Способ получени производных тиено (3,2-с)пиридина или их солей |
| HU76PA1233A HU174050B (hu) | 1975-02-07 | 1976-02-03 | Sposob poluchenija proizvodnykh tienopiridina |
| AT75976A AT345831B (de) | 1975-02-07 | 1976-02-03 | Verfahren zur herstellung von 4,5,6,7- tetrahydrothieno (3,2-c) pyridinderivaten |
| DK46376AA DK136653B (da) | 1975-02-07 | 1976-02-04 | Fremgangsmåde til fremstilling af thieno-pyridinderivater. |
| DE2604248A DE2604248C2 (de) | 1975-02-07 | 1976-02-04 | Verfahren zur Herstellung von Thienopyridinderivaten |
| MX000897U MX3207E (es) | 1975-02-07 | 1976-02-04 | Procedimiento para la preparacion de derivados de la tieno - piridina |
| YU267/76A YU39610B (en) | 1975-02-07 | 1976-02-04 | Process for obtaining thieno-pyridine derivatives |
| CA245,134A CA1071630A (en) | 1975-02-07 | 1976-02-05 | Process for the preparation of thienopyridine derivatives |
| DD191118A DD122977A5 (de) | 1975-02-07 | 1976-02-05 | Verfahren zur herstellung von thieno-pyridin-derivaten |
| PH18060A PH14038A (en) | 1975-02-07 | 1976-02-05 | Process for the preparation of thieno pyridine derivatives |
| SE7601247A SE421621B (sv) | 1975-02-07 | 1976-02-05 | Forfarande for framstellning av tienopyridinderivat |
| RO7684707A RO68148A (ro) | 1975-02-07 | 1976-02-06 | Procedeu pentru prepararea unor derivati ai 4,5,6,7-tetrahidro-tieno-(3,2-c)-piridinei |
| AU10911/76A AU496832B2 (en) | 1975-02-07 | 1976-02-06 | Process for the preparation of thieno pyridine derivatives |
| PL1976187055A PL97671B1 (pl) | 1975-02-07 | 1976-02-06 | Sposob wytwarzania pochodnych tienopirydyny |
| BE164136A BE838327A (fr) | 1975-02-07 | 1976-02-06 | Procede de preparation de derives de la thienopyridine |
| GB477276A GB1477990A (en) | 1975-02-07 | 1976-02-06 | Process for the preparation of thieno-pyridine derivatives |
| PT64782A PT64782B (fr) | 1975-02-07 | 1976-02-06 | Procede de preparation de derives de la thieno-pyridine |
| JP51012735A JPS5931513B2 (ja) | 1975-02-07 | 1976-02-06 | チエノ−ビリジン誘導体の製造方法 |
| US05/775,314 US4127580A (en) | 1975-02-07 | 1977-03-07 | Process for the preparation of thieno-pyridine derivatives |
| IT7949198A IT7949198A0 (it) | 1975-02-07 | 1979-05-28 | Procedimento per preparare derivati di tieno-piridina |
| JP8975379A JPS5533469A (en) | 1975-02-07 | 1979-07-14 | Thiophene derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7503968A FR2300090A1 (fr) | 1975-02-07 | 1975-02-07 | Procede de preparation de derives de la thienopyridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2300090A1 true FR2300090A1 (fr) | 1976-09-03 |
| FR2300090B1 FR2300090B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-03-16 |
Family
ID=9150954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7503968A Granted FR2300090A1 (fr) | 1975-02-07 | 1975-02-07 | Procede de preparation de derives de la thienopyridine |
Country Status (4)
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2508453A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus |
| EP0068979A1 (fr) * | 1981-06-30 | 1983-01-05 | Elf Sanofi | Procédé de préparation de dérivés des (thiényl-2)- et (thiényl-3)-2 éthylamines et produits ainsi obtenus |
| EP0321349A1 (fr) | 1987-12-18 | 1989-06-21 | Elf Sanofi | Procédé de préparation de la N-(chloro-2 benzyl) (thiényl-2)-2 éthylamine |
| EP0439404A3 (en) * | 1990-01-25 | 1992-04-08 | Sanofi | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno (3,2-c) pyridine derivatives therefrom |
| EP0522956A3 (en) * | 1991-07-08 | 1993-04-07 | Elf Sanofi | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno (3,2-c) pyridine derivatives therefrom |
-
1975
- 1975-02-07 FR FR7503968A patent/FR2300090A1/fr active Granted
-
1976
- 1976-01-28 ZA ZA760474A patent/ZA76474B/xx unknown
- 1976-02-06 BE BE164136A patent/BE838327A/xx not_active IP Right Cessation
-
1979
- 1979-07-14 JP JP8975379A patent/JPS5533469A/ja active Granted
Non-Patent Citations (1)
| Title |
|---|
| NEANT * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2508453A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus |
| EP0068978A1 (fr) * | 1981-06-30 | 1983-01-05 | Elf Sanofi | Procédé de préparation de dérivés des (thiényl-2)- et (thiényl-3)-2 éthylamines, et produits ainsi obtenus |
| EP0068979A1 (fr) * | 1981-06-30 | 1983-01-05 | Elf Sanofi | Procédé de préparation de dérivés des (thiényl-2)- et (thiényl-3)-2 éthylamines et produits ainsi obtenus |
| EP0321349A1 (fr) | 1987-12-18 | 1989-06-21 | Elf Sanofi | Procédé de préparation de la N-(chloro-2 benzyl) (thiényl-2)-2 éthylamine |
| FR2624860A1 (fr) * | 1987-12-18 | 1989-06-23 | Sanofi Sa | Procede de preparation de la n-(chloro-2 benzyl) (thienyl-2)-2 ethylamine |
| US4873343A (en) * | 1987-12-18 | 1989-10-10 | Sanofi | Process for the preparation of N-(2-chlorobenzyl)-2-(2-thienyl) ethylamine |
| EP0321349B1 (fr) * | 1987-12-18 | 1992-04-15 | Elf Sanofi | Procédé de préparation de la N-(chloro-2 benzyl) (thiényl-2)-2 éthylamine |
| EP0439404A3 (en) * | 1990-01-25 | 1992-04-08 | Sanofi | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno (3,2-c) pyridine derivatives therefrom |
| EP0522956A3 (en) * | 1991-07-08 | 1993-04-07 | Elf Sanofi | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno (3,2-c) pyridine derivatives therefrom |
Also Published As
| Publication number | Publication date |
|---|---|
| BE838327A (fr) | 1976-08-06 |
| JPS562068B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-01-17 |
| ZA76474B (en) | 1977-03-30 |
| FR2300090B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-03-16 |
| JPS5533469A (en) | 1980-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CA | Change of address | ||
| CD | Change of name or company name | ||
| TP | Transmission of property | ||
| CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0248, 920521 |
|
| CA | Change of address | ||
| CD | Change of name or company name | ||
| CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0248, 750207 |
|
| CL | Concession to grant licences |