IE34651L - Heterocyclic compounds. - Google Patents

Heterocyclic compounds.

Info

Publication number
IE34651L
IE34651L IE137870A IE137870A IE34651L IE 34651 L IE34651 L IE 34651L IE 137870 A IE137870 A IE 137870A IE 137870 A IE137870 A IE 137870A IE 34651 L IE34651 L IE 34651L
Authority
IE
Ireland
Prior art keywords
alkyl
cpds
rmghal
substd
prepd
Prior art date
Application number
IE137870A
Other versions
IE34651B1 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IE34651L publication Critical patent/IE34651L/en
Publication of IE34651B1 publication Critical patent/IE34651B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines

Abstract

Antiinflammatory substd benzothiazines Title cpds of formula (I) (where X is H, halogen, OH, NO2, NH2, alkyl, haloalkyl, alkoxy, alkylthio, alkylsylphonyl alkanoylamino or mono-or dialkyl- amino (alkyl is not >8C) Y is O,S, CH2, (CH2)2, SO, SO2 or a direct bond, R is not >8C alkyl, 3-8C cycloalkyl or is not >10C aryl or aralkyl, Z is in which R is as above and R' is H, vinyl alkyl, phenyl, pyridyl, furyl, naphthyl, thienyl, X-substd phenl, alkylene-dioxy phenyl, is not >8C alkyl, 3-8C cycloalkyl or is not >10C aralkyl, Ar is mono- or bicyclic aryl, 'alkylene' is a is not 6C hydrocarbon chain, and B is a basic N-contng residue) and their acid addition and quaternary ammonium salts are claimed. Cpds (I) where Z is CO are prepd by reacting a cpd. (II) with RMgHal and reacting the resulting cpd. (III) with aqs. NH4Cl (R-Li may be used instead of RMgHal. Other cpds (I) may be prepd by appropriate further reaction of (I; Z = CO). [FR2070172A1]
IE137870A 1969-10-28 1970-10-28 Nitrogen-containing heterocyclic compounds and their preparation IE34651B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87197669A 1969-10-28 1969-10-28
US3559070A 1970-05-07 1970-05-07

Publications (2)

Publication Number Publication Date
IE34651L true IE34651L (en) 1971-04-28
IE34651B1 IE34651B1 (en) 1975-07-09

Family

ID=26712271

Family Applications (1)

Application Number Title Priority Date Filing Date
IE137870A IE34651B1 (en) 1969-10-28 1970-10-28 Nitrogen-containing heterocyclic compounds and their preparation

Country Status (9)

Country Link
JP (1) JPS5022557B1 (en)
BE (1) BE774835A (en)
CA (1) CA948626A (en)
CH (1) CH543512A (en)
DE (1) DE2051474A1 (en)
FR (1) FR2070172A1 (en)
HU (1) HU163349B (en)
IE (1) IE34651B1 (en)
NL (1) NL7015698A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5179000A (en) 1999-06-03 2000-12-28 Basf Aktiengesellschaft Benzothiazinone and benzoxazinone compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1263227A (en) * 1959-02-24 1961-06-09 Olin Mathieson Process for the preparation of new benzothiazepine derivatives

Also Published As

Publication number Publication date
DE2051474A1 (en) 1971-05-06
HU163349B (en) 1973-07-28
FR2070172A1 (en) 1971-09-10
BE774835A (en) 1972-05-03
NL7015698A (en) 1971-05-03
CH543512A (en) 1973-10-31
CA948626A (en) 1974-06-04
JPS5022557B1 (en) 1975-07-31
IE34651B1 (en) 1975-07-09
FR2070172B1 (en) 1974-08-30

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