FR2295750A1 - Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation - Google Patents

Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation

Info

Publication number
FR2295750A1
FR2295750A1 FR7539341A FR7539341A FR2295750A1 FR 2295750 A1 FR2295750 A1 FR 2295750A1 FR 7539341 A FR7539341 A FR 7539341A FR 7539341 A FR7539341 A FR 7539341A FR 2295750 A1 FR2295750 A1 FR 2295750A1
Authority
FR
France
Prior art keywords
benzylpyrimidines
useful
new
preparation process
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7539341A
Other languages
English (en)
French (fr)
Other versions
FR2295750B1 (nl
Inventor
Ivan Kompis
Gerald Rey-Bellet
Guido Zanetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2295750A1 publication Critical patent/FR2295750A1/fr
Application granted granted Critical
Publication of FR2295750B1 publication Critical patent/FR2295750B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
FR7539341A 1974-12-24 1975-12-22 Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation Granted FR2295750A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (nl) 1974-12-24 1974-12-24

Publications (2)

Publication Number Publication Date
FR2295750A1 true FR2295750A1 (fr) 1976-07-23
FR2295750B1 FR2295750B1 (nl) 1980-06-20

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7539341A Granted FR2295750A1 (fr) 1974-12-24 1975-12-22 Nouvelles benzylpyrimidines utiles en tant que medicaments et leur procede de preparation

Country Status (25)

Country Link
JP (1) JPS5191273A (nl)
AT (1) AT344704B (nl)
AU (1) AU500102B2 (nl)
BE (1) BE836996A (nl)
BR (1) BR7508534A (nl)
CA (1) CA1059127A (nl)
CH (2) CH605828A5 (nl)
CU (1) CU34406A (nl)
DD (1) DD123603A5 (nl)
DE (1) DE2558150A1 (nl)
DK (1) DK137797B (nl)
ES (1) ES443790A1 (nl)
FI (1) FI753312A (nl)
FR (1) FR2295750A1 (nl)
GB (1) GB1492140A (nl)
HU (1) HU174324B (nl)
IL (1) IL48416A (nl)
LU (1) LU73971A1 (nl)
NL (1) NL7514269A (nl)
NO (1) NO141408C (nl)
PH (1) PH12314A (nl)
PL (1) PL101046B1 (nl)
SE (1) SE417607B (nl)
SU (1) SU612629A3 (nl)
ZA (1) ZA756964B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422647A1 (fr) * 1977-11-10 1979-11-09 Hoffmann La Roche Nouvelles 2,4-diamino-5-benzylpyrimidines, leur preparation et leur application en tant que medicaments

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ713361A (en) 2009-08-17 2017-06-30 Memorial Sloan Kettering Cancer Center Heat shock protein binding compounds, compositions, and methods for making and using same
EP3143013B1 (en) 2014-05-13 2019-12-18 Memorial Sloan Kettering Cancer Center Hsp70 modulators and methods for making and using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422647A1 (fr) * 1977-11-10 1979-11-09 Hoffmann La Roche Nouvelles 2,4-diamino-5-benzylpyrimidines, leur preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
PH12314A (en) 1979-01-16
GB1492140A (en) 1977-11-16
ZA756964B (en) 1976-10-27
DE2558150A1 (de) 1976-07-01
AU8643375A (en) 1977-05-12
LU73971A1 (nl) 1977-07-01
BE836996A (fr) 1976-06-23
DD123603A5 (nl) 1977-01-05
SE417607B (sv) 1981-03-30
FI753312A (nl) 1976-06-25
NO141408C (no) 1980-03-05
NO754372L (nl) 1976-06-25
AT344704B (de) 1978-08-10
CH605828A5 (nl) 1978-10-13
BR7508534A (pt) 1976-12-21
ATA975975A (de) 1977-12-15
CH617191A5 (en) 1980-05-14
FR2295750B1 (nl) 1980-06-20
DK137797B (da) 1978-05-08
CA1059127A (en) 1979-07-24
SE7514642L (sv) 1976-06-28
AU500102B2 (en) 1979-05-10
DK589675A (nl) 1976-06-25
NO141408B (no) 1979-11-26
SU612629A3 (ru) 1978-06-25
CU34406A (es) 1978-09-08
HU174324B (hu) 1979-12-28
IL48416A (en) 1980-02-29
PL101046B1 (pl) 1978-11-30
IL48416A0 (en) 1976-01-30
JPS5191273A (nl) 1976-08-10
ES443790A1 (es) 1977-12-16
DK137797C (nl) 1978-10-16
NL7514269A (nl) 1976-06-28

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Legal Events

Date Code Title Description
ST Notification of lapse