FR2275452A1 - Intermediaires a groupement tetrahydropyranyle utiles dans la synthese de prostaglandines - Google Patents

Intermediaires a groupement tetrahydropyranyle utiles dans la synthese de prostaglandines

Info

Publication number
FR2275452A1
FR2275452A1 FR7525565A FR7525565A FR2275452A1 FR 2275452 A1 FR2275452 A1 FR 2275452A1 FR 7525565 A FR7525565 A FR 7525565A FR 7525565 A FR7525565 A FR 7525565A FR 2275452 A1 FR2275452 A1 FR 2275452A1
Authority
FR
France
Prior art keywords
intermediaries
prostaglandins
synthesis
tetrahydropyranyl group
group useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7525565A
Other languages
English (en)
Other versions
FR2275452B1 (fr
Inventor
Michael Ross Johnson
Thomas Ken Schaaf
Jasjit Singh Bindra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2275452A1 publication Critical patent/FR2275452A1/fr
Application granted granted Critical
Publication of FR2275452B1 publication Critical patent/FR2275452B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds
FR7525565A 1972-11-08 1975-08-18 Intermediaires a groupement tetrahydropyranyle utiles dans la synthese de prostaglandines Granted FR2275452A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30481572A 1972-11-08 1972-11-08

Publications (2)

Publication Number Publication Date
FR2275452A1 true FR2275452A1 (fr) 1976-01-16
FR2275452B1 FR2275452B1 (fr) 1977-12-16

Family

ID=23178143

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7339759A Expired FR2205339B1 (fr) 1972-11-08 1973-11-08
FR7525565A Granted FR2275452A1 (fr) 1972-11-08 1975-08-18 Intermediaires a groupement tetrahydropyranyle utiles dans la synthese de prostaglandines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7339759A Expired FR2205339B1 (fr) 1972-11-08 1973-11-08

Country Status (24)

Country Link
JP (1) JPS5644068B2 (fr)
AR (2) AR204816A1 (fr)
AT (1) AT347607B (fr)
BE (1) BE807047A (fr)
CA (1) CA1027559A (fr)
CH (1) CH601222A5 (fr)
CS (1) CS188175B2 (fr)
DD (2) DD111370A5 (fr)
DE (2) DE2365999A1 (fr)
ES (2) ES420326A1 (fr)
FI (1) FI58116C (fr)
FR (2) FR2205339B1 (fr)
GB (1) GB1456511A (fr)
HU (2) HU171818B (fr)
IE (1) IE39686B1 (fr)
IL (1) IL43553A (fr)
IN (1) IN139905B (fr)
NL (1) NL7315240A (fr)
NO (2) NO145437C (fr)
PH (2) PH15504A (fr)
SE (2) SE420198B (fr)
SU (2) SU538659A3 (fr)
YU (2) YU287973A (fr)
ZA (1) ZA738593B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361381A1 (fr) * 1972-07-13 1978-03-10 Pfizer Ethers tetrahydropyranyliques, utiles comme intermediaires de synthese de prostaglandines
US3929862A (en) * 1974-01-08 1975-12-30 Upjohn Co Substituted tolylesters of PGF{HD 2{B {60
US3998869A (en) * 1974-11-14 1976-12-21 The Upjohn Company Substituted anilide esters of 16-substituted PGE2
DE2737807A1 (de) * 1976-08-27 1978-03-09 Pfizer C tief 1 -p-biphenylester von omega-pentanorprostaglandinen
US6531504B2 (en) * 2001-05-17 2003-03-11 Allergan, Inc. Prostanoic acid derivatives as agents for lowering intraocular pressure

Also Published As

Publication number Publication date
NO146280C (no) 1982-09-01
JPS49100060A (fr) 1974-09-20
JPS5644068B2 (fr) 1981-10-16
NO145437C (no) 1982-03-24
AR202311A1 (es) 1975-05-30
SE420198B (sv) 1981-09-21
CH601222A5 (fr) 1978-06-30
HU171945B (hu) 1978-04-28
DE2355042A1 (de) 1974-05-22
PH13794A (en) 1980-10-01
NL7315240A (fr) 1974-05-10
FR2275452B1 (fr) 1977-12-16
CS188175B2 (en) 1979-02-28
HU171818B (hu) 1978-03-28
IN139905B (fr) 1976-08-14
IE39686L (en) 1974-05-08
NO146280B (no) 1982-05-24
FR2205339A1 (fr) 1974-05-31
CA1027559A (fr) 1978-03-07
DD111370A5 (fr) 1975-02-12
ATA937173A (de) 1978-05-15
IE39686B1 (en) 1978-12-06
AT347607B (de) 1979-01-10
DE2365999A1 (de) 1977-05-12
PH15504A (en) 1983-02-03
FI58116B (fi) 1980-08-29
NO743588L (no) 1974-05-09
FI58116C (fi) 1980-12-10
IL43553A0 (en) 1974-03-14
SE7704369L (sv) 1977-04-15
FR2205339B1 (fr) 1980-01-04
YU287973A (en) 1982-02-25
IL43553A (en) 1979-10-31
SU538659A3 (ru) 1976-12-05
DD113211A5 (fr) 1975-05-20
AR204816A1 (es) 1976-03-05
ZA738593B (en) 1974-10-30
NO145437B (no) 1981-12-14
SU1021340A3 (ru) 1983-05-30
GB1456511A (en) 1976-11-24
ES434687A1 (es) 1976-12-16
ES420326A1 (es) 1976-03-16
YU264480A (en) 1983-04-27
BE807047A (fr) 1974-05-08
AU6222573A (en) 1975-05-08

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Legal Events

Date Code Title Description
ST Notification of lapse