FR2272994A1 - Ethylene glycol mixed ester with clofibric and nicotinic acids - prepd by reacting ethylene chlorohydrin with a clofibric acid salt and nicotinoyl chloride - Google Patents
Ethylene glycol mixed ester with clofibric and nicotinic acids - prepd by reacting ethylene chlorohydrin with a clofibric acid salt and nicotinoyl chlorideInfo
- Publication number
- FR2272994A1 FR2272994A1 FR7513271A FR7513271A FR2272994A1 FR 2272994 A1 FR2272994 A1 FR 2272994A1 FR 7513271 A FR7513271 A FR 7513271A FR 7513271 A FR7513271 A FR 7513271A FR 2272994 A1 FR2272994 A1 FR 2272994A1
- Authority
- FR
- France
- Prior art keywords
- clofibric
- prepd
- acid salt
- mixed ester
- nicotinoyl chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical class OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 title abstract 3
- 150000002148 esters Chemical class 0.000 title abstract 2
- ATBIAJXSKNPHEI-UHFFFAOYSA-N pyridine-3-carbonyl chloride Chemical compound ClC(=O)C1=CC=CN=C1 ATBIAJXSKNPHEI-UHFFFAOYSA-N 0.000 title abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 title 3
- SZIFAVKTNFCBPC-UHFFFAOYSA-N 2-chloroethanol Chemical compound OCCCl SZIFAVKTNFCBPC-UHFFFAOYSA-N 0.000 title 1
- 150000002814 niacins Chemical class 0.000 title 1
- 235000001968 nicotinic acid Nutrition 0.000 title 1
- 239000003315 2-(4-chlorophenoxy)-2-methylpropanoic acid Substances 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229950008441 clofibric acid Drugs 0.000 abstract 1
- -1 hydroxyethyl ester Chemical class 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES426755A ES426755A1 (es) | 1974-05-29 | 1974-05-29 | Un procedimiento de preparacion del ester mixto 1 - 2 - (p-clorofenoxi) - 2 - metilpropianoato, 2 - nicotinato de eti- lenglicol. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2272994A1 true FR2272994A1 (en) | 1975-12-26 |
| FR2272994B1 FR2272994B1 (enExample) | 1978-02-24 |
Family
ID=8466799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7513271A Granted FR2272994A1 (en) | 1974-05-29 | 1975-04-28 | Ethylene glycol mixed ester with clofibric and nicotinic acids - prepd by reacting ethylene chlorohydrin with a clofibric acid salt and nicotinoyl chloride |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS511479A (enExample) |
| DE (1) | DE2519535A1 (enExample) |
| ES (1) | ES426755A1 (enExample) |
| FR (1) | FR2272994A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES469531A1 (es) * | 1978-05-05 | 1978-12-01 | Alter Lab | Un procedimiento de preparacion de ciertos diesteres de eti-lenglicol. |
| JPS60222445A (ja) * | 1984-04-19 | 1985-11-07 | Yoshitomi Pharmaceut Ind Ltd | フタル酸化合物 |
-
1974
- 1974-05-29 ES ES426755A patent/ES426755A1/es not_active Expired
-
1975
- 1975-04-28 FR FR7513271A patent/FR2272994A1/fr active Granted
- 1975-05-02 DE DE19752519535 patent/DE2519535A1/de active Pending
- 1975-05-26 JP JP50063385A patent/JPS511479A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2519535A1 (de) | 1975-12-04 |
| FR2272994B1 (enExample) | 1978-02-24 |
| ES426755A1 (es) | 1976-07-16 |
| JPS511479A (en) | 1976-01-08 |
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