FR2272678A1 - N(6)-Disubstd. adenosine derivs - prepd. by reacting 6-(reactively substd.) purine ribosides with secondary amines - Google Patents
N(6)-Disubstd. adenosine derivs - prepd. by reacting 6-(reactively substd.) purine ribosides with secondary aminesInfo
- Publication number
- FR2272678A1 FR2272678A1 FR7516924A FR7516924A FR2272678A1 FR 2272678 A1 FR2272678 A1 FR 2272678A1 FR 7516924 A FR7516924 A FR 7516924A FR 7516924 A FR7516924 A FR 7516924A FR 2272678 A1 FR2272678 A1 FR 2272678A1
- Authority
- FR
- France
- Prior art keywords
- adenosine
- derivs
- prepd
- reacting
- disubstd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title abstract 6
- 239000002126 C01EB10 - Adenosine Substances 0.000 title abstract 3
- 229960005305 adenosine Drugs 0.000 title abstract 3
- KDCGOANMDULRCW-UHFFFAOYSA-N Purine Natural products N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 title 1
- -1 purine ribosides Chemical class 0.000 title 1
- 150000003335 secondary amines Chemical class 0.000 title 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000326 anti-hypercholesterolaemic effect Effects 0.000 abstract 1
- 230000001315 anti-hyperlipaemic effect Effects 0.000 abstract 1
- 230000003243 anti-lipolytic effect Effects 0.000 abstract 1
- 150000001602 bicycloalkyls Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742426682 DE2426682A1 (de) | 1974-06-01 | 1974-06-01 | Neue n(6)-disubstituierte adenosinderivate und verfahren zur herstellung derselben |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2272678A1 true FR2272678A1 (en) | 1975-12-26 |
Family
ID=5917125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7516924A Withdrawn FR2272678A1 (en) | 1974-06-01 | 1975-05-30 | N(6)-Disubstd. adenosine derivs - prepd. by reacting 6-(reactively substd.) purine ribosides with secondary amines |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS511493A (enrdf_load_stackoverflow) |
BE (1) | BE829498A (enrdf_load_stackoverflow) |
DE (1) | DE2426682A1 (enrdf_load_stackoverflow) |
FI (1) | FI751527A7 (enrdf_load_stackoverflow) |
FR (1) | FR2272678A1 (enrdf_load_stackoverflow) |
NL (1) | NL7506427A (enrdf_load_stackoverflow) |
SE (1) | SE7506024L (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985004882A1 (en) * | 1984-04-18 | 1985-11-07 | Nelson Research And Development Company | N-6 substituted adenosine derivatives as cardiac vasodilators |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52108721A (en) * | 1976-03-08 | 1977-09-12 | Nippon Telegr & Teleph Corp <Ntt> | Generating method of time series signal having memory function |
US4657897A (en) * | 1984-06-22 | 1987-04-14 | Warner-Lambert Company | N6 -substituted adenosines for treating pain |
US4600707A (en) * | 1985-01-25 | 1986-07-15 | Warner-Lambert Company | Benzothien-3-yl adenosine; benzothien-3-yl adenosine, S-oxide; and benzothien-3-yl, S,S-dioxide adenosine compounds |
US4636493A (en) * | 1985-01-25 | 1987-01-13 | Warner-Lambert Company | Benzothien-3-yl adenosine; benzothien-3-yl adenosine, S-oxide; and benzothien-3-yl, S,S-dioxide adenosine compounds |
GB8729994D0 (en) * | 1987-12-23 | 1988-02-03 | Glaxo Group Ltd | Chemical compounds |
-
1974
- 1974-06-01 DE DE19742426682 patent/DE2426682A1/de active Pending
-
1975
- 1975-05-26 FI FI751527A patent/FI751527A7/fi not_active Application Discontinuation
- 1975-05-26 BE BE156720A patent/BE829498A/xx unknown
- 1975-05-27 SE SE7506024A patent/SE7506024L/xx not_active Application Discontinuation
- 1975-05-29 JP JP50064780A patent/JPS511493A/ja active Pending
- 1975-05-30 NL NL7506427A patent/NL7506427A/xx unknown
- 1975-05-30 FR FR7516924A patent/FR2272678A1/fr not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985004882A1 (en) * | 1984-04-18 | 1985-11-07 | Nelson Research And Development Company | N-6 substituted adenosine derivatives as cardiac vasodilators |
EP0305643A3 (en) * | 1984-04-18 | 1989-08-30 | Nelson Research & Development Company | N-6 thienyl substituted adenosine derivatives as cardiac vasodilators |
Also Published As
Publication number | Publication date |
---|---|
NL7506427A (nl) | 1975-12-03 |
FI751527A7 (enrdf_load_stackoverflow) | 1975-12-02 |
SE7506024L (sv) | 1975-12-02 |
JPS511493A (en) | 1976-01-08 |
DE2426682A1 (de) | 1975-12-11 |
BE829498A (fr) | 1975-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |