FR2272661A1 - Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines - Google Patents

Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines

Info

Publication number
FR2272661A1
FR2272661A1 FR7516933A FR7516933A FR2272661A1 FR 2272661 A1 FR2272661 A1 FR 2272661A1 FR 7516933 A FR7516933 A FR 7516933A FR 7516933 A FR7516933 A FR 7516933A FR 2272661 A1 FR2272661 A1 FR 2272661A1
Authority
FR
France
Prior art keywords
imidazo
ring
cpds
phthalazines
quinoxalines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7516933A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspro Nicholas Ltd
Original Assignee
Aspro Nicholas Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aspro Nicholas Ltd filed Critical Aspro Nicholas Ltd
Publication of FR2272661A1 publication Critical patent/FR2272661A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. of formula (I) and their acid-addn. and quat. ammonium salts are pharmacologically active - where -X-Z is Ar1, Ar2, indep. is phenyl, hydroxyphenyl or (1-4C alkoxy)-phenyl; U, W indep. is N or CR >=1 being CR; R is H, aryl or a bivalent radical joined to the benzazine ring to form a condensed, aromatic, carbocyclic ring on the benzazine ring and when the molecule carries two R gps. these may be the same or different. The polycyclic ring and any aryl or bivalent radical represented by R may be substd. by one or more pharm. acceptable gps. 2, 3-Diphenylimidazo-(2, 1-a)-isoquinoline; 2, 3-bis-(p-methoxyphenyl)-imidazo-(2, 1-a)-isoquinoline; 2, 3-bis-(p-methoxyphenyl)-imidazo-(2, 1-a)-phthalazine and their quaternary ammonium and acid addn. salts, are specif. claimed. Cpds. (I) are useful as antiinflammatories which are administered in formulations and dosages similar to those of the analogous cpds. described in GB 1347493.
FR7516933A 1974-05-31 1975-05-30 Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines Withdrawn FR2272661A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2421074 1974-05-31

Publications (1)

Publication Number Publication Date
FR2272661A1 true FR2272661A1 (en) 1975-12-26

Family

ID=10208119

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7516933A Withdrawn FR2272661A1 (en) 1974-05-31 1975-05-30 Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines

Country Status (8)

Country Link
JP (1) JPS516997A (en)
AU (1) AU8162975A (en)
BE (1) BE829522A (en)
DE (1) DE2523876A1 (en)
DK (1) DK236175A (en)
FR (1) FR2272661A1 (en)
NL (1) NL7506327A (en)
ZA (1) ZA753363B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8415540D0 (en) * 1984-06-18 1984-07-25 Fujisawa Pharmaceutical Co Imidazoisoquinoline compounds
GB0017543D0 (en) * 2000-07-17 2000-09-06 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
DE2523876A1 (en) 1976-01-15
DK236175A (en) 1975-12-01
AU8162975A (en) 1976-12-02
BE829522A (en) 1975-11-27
NL7506327A (en) 1975-12-02
ZA753363B (en) 1976-05-26
JPS516997A (en) 1976-01-20

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Legal Events

Date Code Title Description
ST Notification of lapse