FR2272661A1 - Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines - Google Patents
Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolinesInfo
- Publication number
- FR2272661A1 FR2272661A1 FR7516933A FR7516933A FR2272661A1 FR 2272661 A1 FR2272661 A1 FR 2272661A1 FR 7516933 A FR7516933 A FR 7516933A FR 7516933 A FR7516933 A FR 7516933A FR 2272661 A1 FR2272661 A1 FR 2272661A1
- Authority
- FR
- France
- Prior art keywords
- imidazo
- ring
- cpds
- phthalazines
- quinoxalines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Cpds. of formula (I) and their acid-addn. and quat. ammonium salts are pharmacologically active - where -X-Z is Ar1, Ar2, indep. is phenyl, hydroxyphenyl or (1-4C alkoxy)-phenyl; U, W indep. is N or CR >=1 being CR; R is H, aryl or a bivalent radical joined to the benzazine ring to form a condensed, aromatic, carbocyclic ring on the benzazine ring and when the molecule carries two R gps. these may be the same or different. The polycyclic ring and any aryl or bivalent radical represented by R may be substd. by one or more pharm. acceptable gps. 2, 3-Diphenylimidazo-(2, 1-a)-isoquinoline; 2, 3-bis-(p-methoxyphenyl)-imidazo-(2, 1-a)-isoquinoline; 2, 3-bis-(p-methoxyphenyl)-imidazo-(2, 1-a)-phthalazine and their quaternary ammonium and acid addn. salts, are specif. claimed. Cpds. (I) are useful as antiinflammatories which are administered in formulations and dosages similar to those of the analogous cpds. described in GB 1347493.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2421074 | 1974-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2272661A1 true FR2272661A1 (en) | 1975-12-26 |
Family
ID=10208119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7516933A Withdrawn FR2272661A1 (en) | 1974-05-31 | 1975-05-30 | Anti-inflammatory diphenyl imidazo-isoquinolines - imidazo-phthalazines, imidazo-quinolines, imidazo-quinoxalines and imidazo-quinazolines |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS516997A (en) |
AU (1) | AU8162975A (en) |
BE (1) | BE829522A (en) |
DE (1) | DE2523876A1 (en) |
DK (1) | DK236175A (en) |
FR (1) | FR2272661A1 (en) |
NL (1) | NL7506327A (en) |
ZA (1) | ZA753363B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8415540D0 (en) * | 1984-06-18 | 1984-07-25 | Fujisawa Pharmaceutical Co | Imidazoisoquinoline compounds |
GB0017543D0 (en) | 2000-07-17 | 2000-09-06 | Merck Sharp & Dohme | Therapeutic agents |
-
1975
- 1975-05-26 ZA ZA00753363A patent/ZA753363B/en unknown
- 1975-05-27 BE BE156733A patent/BE829522A/en unknown
- 1975-05-28 AU AU81629/75A patent/AU8162975A/en not_active Expired
- 1975-05-28 DK DK236175A patent/DK236175A/en unknown
- 1975-05-29 NL NL7506327A patent/NL7506327A/en unknown
- 1975-05-30 DE DE19752523876 patent/DE2523876A1/en active Pending
- 1975-05-30 FR FR7516933A patent/FR2272661A1/en not_active Withdrawn
- 1975-05-30 JP JP50065204A patent/JPS516997A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU8162975A (en) | 1976-12-02 |
DE2523876A1 (en) | 1976-01-15 |
DK236175A (en) | 1975-12-01 |
BE829522A (en) | 1975-11-27 |
JPS516997A (en) | 1976-01-20 |
ZA753363B (en) | 1976-05-26 |
NL7506327A (en) | 1975-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |