FR2260330A1 - Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index - Google Patents
Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic indexInfo
- Publication number
- FR2260330A1 FR2260330A1 FR7404096A FR7404096A FR2260330A1 FR 2260330 A1 FR2260330 A1 FR 2260330A1 FR 7404096 A FR7404096 A FR 7404096A FR 7404096 A FR7404096 A FR 7404096A FR 2260330 A1 FR2260330 A1 FR 2260330A1
- Authority
- FR
- France
- Prior art keywords
- pyridoxine
- hypolipaemiant
- therapeutic index
- hypocholesterolemiant
- nicotinate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 title abstract 6
- 235000008160 pyridoxine Nutrition 0.000 title abstract 3
- 239000011677 pyridoxine Substances 0.000 title abstract 3
- 229940011671 vitamin b6 Drugs 0.000 title abstract 3
- 231100001274 therapeutic index Toxicity 0.000 title abstract 2
- 235000001968 nicotinic acid Nutrition 0.000 title 1
- 239000011664 nicotinic acid Substances 0.000 title 1
- 230000001476 alcoholic effect Effects 0.000 abstract 2
- 206010052895 Coronary artery insufficiency Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- -1 ethyl 2-p-chlorophenoxy isobutyl Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7404096A FR2260330A1 (en) | 1974-02-07 | 1974-02-07 | Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7404096A FR2260330A1 (en) | 1974-02-07 | 1974-02-07 | Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2260330A1 true FR2260330A1 (en) | 1975-09-05 |
| FR2260330B1 FR2260330B1 (en, 2012) | 1977-11-04 |
Family
ID=9134613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7404096A Granted FR2260330A1 (en) | 1974-02-07 | 1974-02-07 | Pyridoxine N-oxy nicotinate - hypolipaemiant and hypocholesterolemiant of good therapeutic index |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2260330A1 (en, 2012) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994019324A1 (en) * | 1993-02-23 | 1994-09-01 | Laboratori Baldacci Spa | Process for the preparation of pyridoxine 5-oxo-2-pyrrolidone carboxylate |
| WO2011147772A1 (en) | 2010-05-25 | 2011-12-01 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists |
| WO2013014060A1 (en) | 2011-07-26 | 2013-01-31 | Boehringer Ingelheim International Gmbh | Substituted quinolines and their use as medicaments |
| WO2015140054A1 (en) | 2014-03-19 | 2015-09-24 | Boehringer Ingelheim International Gmbh | Heteroaryl syk inhibitors |
-
1974
- 1974-02-07 FR FR7404096A patent/FR2260330A1/fr active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994019324A1 (en) * | 1993-02-23 | 1994-09-01 | Laboratori Baldacci Spa | Process for the preparation of pyridoxine 5-oxo-2-pyrrolidone carboxylate |
| WO2011147772A1 (en) | 2010-05-25 | 2011-12-01 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists |
| WO2013014060A1 (en) | 2011-07-26 | 2013-01-31 | Boehringer Ingelheim International Gmbh | Substituted quinolines and their use as medicaments |
| WO2015140054A1 (en) | 2014-03-19 | 2015-09-24 | Boehringer Ingelheim International Gmbh | Heteroaryl syk inhibitors |
| WO2015140051A1 (en) | 2014-03-19 | 2015-09-24 | Boehringer Ingelheim International Gmbh | Heteroaryl sik inhibitors |
| WO2015140055A1 (en) | 2014-03-19 | 2015-09-24 | Boehringer Ingelheim International Gmbh | Heteroaryl syk inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2260330B1 (en, 2012) | 1977-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |