FR2113947A1 - Oral raubasine compositions - also contg polyethylene glycol to improve resorption - Google Patents
Oral raubasine compositions - also contg polyethylene glycol to improve resorptionInfo
- Publication number
- FR2113947A1 FR2113947A1 FR7140569A FR7140569A FR2113947A1 FR 2113947 A1 FR2113947 A1 FR 2113947A1 FR 7140569 A FR7140569 A FR 7140569A FR 7140569 A FR7140569 A FR 7140569A FR 2113947 A1 FR2113947 A1 FR 2113947A1
- Authority
- FR
- France
- Prior art keywords
- raubasine
- polyethylene glycol
- contg
- oral
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Compsns. produced by homogeneously mixing raubasine with polyethylene glycol of mean mol. wt. 4000-25000 and compressing to tablets or granules are useful in the treatment of arterial hypertension and arterial and venous circulatory disorders and give better GI-absorption of raubasine than previously used oral preparations. Further additives may be incorporated into the compsns., particularly wetting agents, whic shorten the disintegration time of the compsn. and further improve resorption, as well as additional active substances, esp. methyldigoxin or digoxin.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19702055930 DE2055930A1 (en) | 1970-11-13 | 1970-11-13 | Improved oral application form of Raubasin |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2113947A1 true FR2113947A1 (en) | 1972-06-30 |
FR2113947B1 FR2113947B1 (en) | 1975-10-31 |
Family
ID=5788038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7140569A Granted FR2113947A1 (en) | 1970-11-13 | 1971-11-12 | Oral raubasine compositions - also contg polyethylene glycol to improve resorption |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS5511645B1 (en) |
AT (1) | AT309690B (en) |
DE (1) | DE2055930A1 (en) |
FR (1) | FR2113947A1 (en) |
NL (1) | NL7115494A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2204425A1 (en) * | 1972-10-31 | 1974-05-24 | Hoechst Ag | |
EP0381182A2 (en) * | 1989-01-31 | 1990-08-08 | Ipa Internationale Pharma Agentur Gmbh | An erosion-controlled release system for active agents and a process for its preparation |
FR2671727A1 (en) * | 1991-01-18 | 1992-07-24 | Nawrocki Thadee | Use of raubasine for treating poor iron metabolism |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4311694A (en) | 1979-12-31 | 1982-01-19 | American Cyanamid Company | Amorphous coprecipitates of 4-(monoalkylamino) benzoic acid and derivatives and certain water-soluble materials |
-
1970
- 1970-11-13 DE DE19702055930 patent/DE2055930A1/en active Pending
-
1971
- 1971-11-11 NL NL7115494A patent/NL7115494A/xx unknown
- 1971-11-12 AT AT979271A patent/AT309690B/en not_active IP Right Cessation
- 1971-11-12 FR FR7140569A patent/FR2113947A1/en active Granted
- 1971-11-13 JP JP9103871A patent/JPS5511645B1/ja active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2204425A1 (en) * | 1972-10-31 | 1974-05-24 | Hoechst Ag | |
EP0381182A2 (en) * | 1989-01-31 | 1990-08-08 | Ipa Internationale Pharma Agentur Gmbh | An erosion-controlled release system for active agents and a process for its preparation |
EP0381182A3 (en) * | 1989-01-31 | 1991-01-09 | Ipa Internationale Pharma Agentur Gmbh | An erosion-controlled release system for active agents and a process for its preparation |
FR2671727A1 (en) * | 1991-01-18 | 1992-07-24 | Nawrocki Thadee | Use of raubasine for treating poor iron metabolism |
Also Published As
Publication number | Publication date |
---|---|
AT309690B (en) | 1973-08-27 |
DE2055930A1 (en) | 1972-05-18 |
FR2113947B1 (en) | 1975-10-31 |
NL7115494A (en) | 1972-05-16 |
JPS5511645B1 (en) | 1980-03-26 |
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