FR2187312A1 - Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan - Google Patents

Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan

Info

Publication number
FR2187312A1
FR2187312A1 FR7220126A FR7220126A FR2187312A1 FR 2187312 A1 FR2187312 A1 FR 2187312A1 FR 7220126 A FR7220126 A FR 7220126A FR 7220126 A FR7220126 A FR 7220126A FR 2187312 A1 FR2187312 A1 FR 2187312A1
Authority
FR
France
Prior art keywords
prepd
rapidly
recrystallization
paracetamol
aqueous dioxan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7220126A
Other languages
French (fr)
Other versions
FR2187312B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BLUM JEAN FR
Original Assignee
BLUM JEAN FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BLUM JEAN FR filed Critical BLUM JEAN FR
Priority to FR7220126A priority Critical patent/FR2187312A1/en
Publication of FR2187312A1 publication Critical patent/FR2187312A1/en
Application granted granted Critical
Publication of FR2187312B1 publication Critical patent/FR2187312B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Detergent Compositions (AREA)

Abstract

Rapidly soluble paracetamol, esp. for use in effervescent compsns. also contg. chlorpheniramine maleate and ascorbic acid, is prepd. by dissolving paracetamol in aqueous dioxan at about 95 degrees C, cooling with rapid stirring, and collecting the fine crystals.
FR7220126A 1972-06-05 1972-06-05 Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan Granted FR2187312A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7220126A FR2187312A1 (en) 1972-06-05 1972-06-05 Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7220126A FR2187312A1 (en) 1972-06-05 1972-06-05 Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan

Publications (2)

Publication Number Publication Date
FR2187312A1 true FR2187312A1 (en) 1974-01-18
FR2187312B1 FR2187312B1 (en) 1976-03-05

Family

ID=9099681

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7220126A Granted FR2187312A1 (en) 1972-06-05 1972-06-05 Rapidly-soluble paracetamol - prepd by recrystallization from aqueous dioxan

Country Status (1)

Country Link
FR (1) FR2187312A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011489A1 (en) * 1978-11-16 1980-05-28 Beecham Group Plc An analgesic effervescent powder and process for its preparation
FR2586561A1 (en) * 1985-09-05 1987-03-06 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF PARACETAMOL SPHERICAL AGGLOMERATES AND PRODUCTS OBTAINED
FR2672212A1 (en) * 1991-02-04 1992-08-07 Lille Ii Universite Paracetamol crystals for direct tabletting, process for preparing these crystals and tablet obtained with these crystals
WO2023219592A3 (en) * 2022-05-09 2024-03-14 Atabay Kimya Sanayi Ve Tic. A.S. A tablet composition comprising paracetamol, chlorpheniramine and ascorbic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011489A1 (en) * 1978-11-16 1980-05-28 Beecham Group Plc An analgesic effervescent powder and process for its preparation
FR2586561A1 (en) * 1985-09-05 1987-03-06 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF PARACETAMOL SPHERICAL AGGLOMERATES AND PRODUCTS OBTAINED
EP0219377A1 (en) * 1985-09-05 1987-04-22 Rhone-Poulenc Sante Process for the preparation of spherical paracetamol agglomerates and products obtained thereby
FR2672212A1 (en) * 1991-02-04 1992-08-07 Lille Ii Universite Paracetamol crystals for direct tabletting, process for preparing these crystals and tablet obtained with these crystals
WO2023219592A3 (en) * 2022-05-09 2024-03-14 Atabay Kimya Sanayi Ve Tic. A.S. A tablet composition comprising paracetamol, chlorpheniramine and ascorbic acid

Also Published As

Publication number Publication date
FR2187312B1 (en) 1976-03-05

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Legal Events

Date Code Title Description
ST Notification of lapse