FR2255907A1 - 5-Phenyl-tetrahydro-imidazo (2,1-A)isoquinolin-5-ol derivs - prepd. by reacting 2-(2-imidazolin-2-yl)-benzyl-lithium cpds. with benzoic acid derivs - Google Patents
5-Phenyl-tetrahydro-imidazo (2,1-A)isoquinolin-5-ol derivs - prepd. by reacting 2-(2-imidazolin-2-yl)-benzyl-lithium cpds. with benzoic acid derivsInfo
- Publication number
- FR2255907A1 FR2255907A1 FR7500029A FR7500029A FR2255907A1 FR 2255907 A1 FR2255907 A1 FR 2255907A1 FR 7500029 A FR7500029 A FR 7500029A FR 7500029 A FR7500029 A FR 7500029A FR 2255907 A1 FR2255907 A1 FR 2255907A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- isoquinolin
- prepd
- imidazo
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 title abstract 4
- 239000005711 Benzoic acid Substances 0.000 title abstract 2
- 235000010233 benzoic acid Nutrition 0.000 title abstract 2
- JLHRJIAQCJFODY-UHFFFAOYSA-N 5-phenyl-2,3,6,10b-tetrahydro-1H-imidazo[2,1-a]isoquinolin-5-ol Chemical compound C1(=CC=CC=C1)C1(N2C(C3=CC=CC=C3C1)NCC2)O JLHRJIAQCJFODY-UHFFFAOYSA-N 0.000 title 1
- QSHYCZNRXJFVHT-UHFFFAOYSA-N N1C(=NCC1)C1=C(C[Li])C=CC=C1 Chemical compound N1C(=NCC1)C1=C(C[Li])C=CC=C1 QSHYCZNRXJFVHT-UHFFFAOYSA-N 0.000 title 1
- SMBQBQBNOXIFSF-UHFFFAOYSA-N dilithium Chemical compound [Li][Li] SMBQBQBNOXIFSF-UHFFFAOYSA-N 0.000 abstract 2
- CSNXUYRHPXGSJD-UHFFFAOYSA-N isoquinolin-5-ol Chemical compound N1=CC=C2C(O)=CC=CC2=C1 CSNXUYRHPXGSJD-UHFFFAOYSA-N 0.000 abstract 2
- -1 methylenedioxy Chemical group 0.000 abstract 2
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 239000002830 appetite depressant Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42952674A | 1974-01-02 | 1974-01-02 | |
| US05/520,537 US4101553A (en) | 1974-01-02 | 1974-11-04 | Imidazo[2,1-a]isoquinolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2255907A1 true FR2255907A1 (en) | 1975-07-25 |
Family
ID=27028230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7500029A Withdrawn FR2255907A1 (en) | 1974-01-02 | 1975-01-02 | 5-Phenyl-tetrahydro-imidazo (2,1-A)isoquinolin-5-ol derivs - prepd. by reacting 2-(2-imidazolin-2-yl)-benzyl-lithium cpds. with benzoic acid derivs |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS50105698A (enExample) |
| AU (1) | AU7703574A (enExample) |
| DD (1) | DD116235A5 (enExample) |
| DE (1) | DE2460527A1 (enExample) |
| DK (1) | DK683374A (enExample) |
| FI (1) | FI370674A7 (enExample) |
| FR (1) | FR2255907A1 (enExample) |
| IL (1) | IL46370A0 (enExample) |
| NL (1) | NL7416999A (enExample) |
| NO (1) | NO744667L (enExample) |
| SE (1) | SE7416301L (enExample) |
| YU (1) | YU351974A (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2290901A1 (fr) * | 1974-11-12 | 1976-06-11 | Sandoz Sa | Nouveaux derives de l'imidazo(2,1-a)isoquinoleine, leur preparation et leur application comme medicaments |
| FR2398499A1 (fr) * | 1977-07-25 | 1979-02-23 | Sandoz Sa | Nouvelles compositions pharmaceutiques a base de derives de l'imidazole pour inhiber la secretion de la prolactine |
| FR2412311A1 (fr) * | 1977-12-20 | 1979-07-20 | Sandoz Sa | Nouvelles compositions pharmaceutiques a base d'un derive de l'imidazole |
-
1974
- 1974-12-20 FI FI3706/74A patent/FI370674A7/fi unknown
- 1974-12-20 DE DE19742460527 patent/DE2460527A1/de active Pending
- 1974-12-23 NO NO744667A patent/NO744667L/no unknown
- 1974-12-27 SE SE7416301A patent/SE7416301L/xx unknown
- 1974-12-27 DK DK683374A patent/DK683374A/da unknown
- 1974-12-27 JP JP49149104A patent/JPS50105698A/ja active Pending
- 1974-12-30 YU YU03519/74A patent/YU351974A/xx unknown
- 1974-12-30 NL NL7416999A patent/NL7416999A/xx unknown
- 1974-12-31 AU AU77035/74A patent/AU7703574A/en not_active Expired
- 1974-12-31 IL IL46370A patent/IL46370A0/xx unknown
-
1975
- 1975-01-02 FR FR7500029A patent/FR2255907A1/fr not_active Withdrawn
- 1975-01-02 DD DD183475A patent/DD116235A5/xx unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2290901A1 (fr) * | 1974-11-12 | 1976-06-11 | Sandoz Sa | Nouveaux derives de l'imidazo(2,1-a)isoquinoleine, leur preparation et leur application comme medicaments |
| FR2398499A1 (fr) * | 1977-07-25 | 1979-02-23 | Sandoz Sa | Nouvelles compositions pharmaceutiques a base de derives de l'imidazole pour inhiber la secretion de la prolactine |
| FR2412311A1 (fr) * | 1977-12-20 | 1979-07-20 | Sandoz Sa | Nouvelles compositions pharmaceutiques a base d'un derive de l'imidazole |
Also Published As
| Publication number | Publication date |
|---|---|
| DD116235A5 (enExample) | 1975-11-12 |
| FI370674A7 (enExample) | 1975-07-03 |
| SE7416301L (enExample) | 1975-07-03 |
| AU7703574A (en) | 1976-07-01 |
| IL46370A0 (en) | 1975-08-31 |
| DE2460527A1 (de) | 1975-07-10 |
| NO744667L (enExample) | 1975-07-28 |
| NL7416999A (nl) | 1975-07-04 |
| DK683374A (enExample) | 1975-09-01 |
| YU351974A (en) | 1982-05-31 |
| JPS50105698A (enExample) | 1975-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Withdrawal of published application |