FR2232316B1 - - Google Patents

Info

Publication number
FR2232316B1
FR2232316B1 FR7345342A FR7345342A FR2232316B1 FR 2232316 B1 FR2232316 B1 FR 2232316B1 FR 7345342 A FR7345342 A FR 7345342A FR 7345342 A FR7345342 A FR 7345342A FR 2232316 B1 FR2232316 B1 FR 2232316B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7345342A
Other languages
French (fr)
Other versions
FR2232316A1 (pt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AFFILIATED MED RES
Original Assignee
AFFILIATED MED RES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00315836A external-priority patent/US3839346A/en
Application filed by AFFILIATED MED RES filed Critical AFFILIATED MED RES
Publication of FR2232316A1 publication Critical patent/FR2232316A1/fr
Application granted granted Critical
Publication of FR2232316B1 publication Critical patent/FR2232316B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7345342A 1972-12-18 1973-12-18 Expired FR2232316B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00315836A US3839346A (en) 1972-12-18 1972-12-18 N-substituted pyridone and general method for preparing pyridones
US38065573A 1973-07-19 1973-07-19

Publications (2)

Publication Number Publication Date
FR2232316A1 FR2232316A1 (pt) 1975-01-03
FR2232316B1 true FR2232316B1 (pt) 1978-03-24

Family

ID=26980095

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7345342A Expired FR2232316B1 (pt) 1972-12-18 1973-12-18

Country Status (6)

Country Link
JP (1) JPS4987677A (pt)
DE (2) DE2366349C2 (pt)
ES (1) ES421598A1 (pt)
FR (1) FR2232316B1 (pt)
GB (2) GB1458048A (pt)
NL (1) NL7317316A (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1049411A (en) * 1972-12-18 1979-02-27 Affiliated Medical Research N-substituted pyridone and general method for preparing pyridones
JPS5350179A (en) * 1976-10-15 1978-05-08 Rikagaku Kenkyusho Novel 2-pyridone compounds and their preparation
JP4542743B2 (ja) * 2002-12-26 2010-09-15 Kdl株式会社 ピリドン誘導体の溶液状医薬組成物
EP2591784B1 (en) 2005-05-10 2016-09-14 Intermune, Inc. Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system
MX2007009796A (es) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
CA2726588C (en) 2008-06-03 2019-04-16 Karl Kossen Compounds and methods for treating inflammatory and fibrotic disorders
US10092552B2 (en) * 2011-01-31 2018-10-09 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX2011007675A (es) 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
MX346763B (es) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
EP3126362B1 (en) 2014-04-02 2022-01-12 Intermune, Inc. Anti-fibrotic pyridinones
ITUB20154832A1 (it) 2015-10-29 2017-04-29 Procos Spa Processo per la sintesi di pirfenidone
US20200165203A1 (en) * 2017-07-31 2020-05-28 Washington University Use of pirfenidone and derivatives for modulation of b lymphocyte activity and organ protection from acute tissue damage

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2947755A (en) * 1959-02-05 1960-08-02 Wallace & Tiernan Inc Substituted 1-m-aminophenyl-2-pyridones
US3655897A (en) * 1971-01-25 1972-04-11 Merck & Co Inc Anti-inflammatory agents

Also Published As

Publication number Publication date
GB1458049A (en) 1976-12-08
JPS4987677A (pt) 1974-08-22
DE2362958C2 (de) 1984-06-14
NL7317316A (pt) 1974-06-20
DE2362958A1 (de) 1974-06-27
GB1458048A (en) 1976-12-08
FR2232316A1 (pt) 1975-01-03
AU6374673A (en) 1975-06-19
DE2366349C2 (de) 1986-03-27
ES421598A1 (es) 1977-01-01

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Legal Events

Date Code Title Description
ST Notification of lapse
AR Application made for restoration
DI Inadmissibility of an action of restoration