FR2210607A1 - 4-Chloro-5-sulphamoyl-N-furfuryl-anthranilic acid prepn. - from furfural and 4-chloro-5-sulphamoyl anthranilic acid - Google Patents
4-Chloro-5-sulphamoyl-N-furfuryl-anthranilic acid prepn. - from furfural and 4-chloro-5-sulphamoyl anthranilic acidInfo
- Publication number
- FR2210607A1 FR2210607A1 FR7245527A FR7245527A FR2210607A1 FR 2210607 A1 FR2210607 A1 FR 2210607A1 FR 7245527 A FR7245527 A FR 7245527A FR 7245527 A FR7245527 A FR 7245527A FR 2210607 A1 FR2210607 A1 FR 2210607A1
- Authority
- FR
- France
- Prior art keywords
- sulphamoyl
- chloro
- anthranilic acid
- furfural
- furfuryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The cpd. of formula (I):- is prepd. by reacting furfural with 4-chloro-5-sulphamoyl-anthranilic acid and redn. of the Schiffs base obtd. with a reducing agent. The first stage is pref. at 80-160 degrees C, without diluent an opt. with a solvent and redn. pref. is effected with NaBH4. (I) is used as a diuretic (furosemide).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7245527A FR2210607A1 (en) | 1972-12-20 | 1972-12-20 | 4-Chloro-5-sulphamoyl-N-furfuryl-anthranilic acid prepn. - from furfural and 4-chloro-5-sulphamoyl anthranilic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7245527A FR2210607A1 (en) | 1972-12-20 | 1972-12-20 | 4-Chloro-5-sulphamoyl-N-furfuryl-anthranilic acid prepn. - from furfural and 4-chloro-5-sulphamoyl anthranilic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2210607A1 true FR2210607A1 (en) | 1974-07-12 |
FR2210607B3 FR2210607B3 (en) | 1976-01-09 |
Family
ID=9109054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7245527A Granted FR2210607A1 (en) | 1972-12-20 | 1972-12-20 | 4-Chloro-5-sulphamoyl-N-furfuryl-anthranilic acid prepn. - from furfural and 4-chloro-5-sulphamoyl anthranilic acid |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2210607A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663348A (en) * | 1985-07-02 | 1987-05-05 | Warner-Lambert Co. | Furosemide salts and pharmaceutical preparations thereof |
-
1972
- 1972-12-20 FR FR7245527A patent/FR2210607A1/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663348A (en) * | 1985-07-02 | 1987-05-05 | Warner-Lambert Co. | Furosemide salts and pharmaceutical preparations thereof |
Also Published As
Publication number | Publication date |
---|---|
FR2210607B3 (en) | 1976-01-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |