FR2209560A1 - N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin - Google Patents

N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin

Info

Publication number
FR2209560A1
FR2209560A1 FR7342546A FR7342546A FR2209560A1 FR 2209560 A1 FR2209560 A1 FR 2209560A1 FR 7342546 A FR7342546 A FR 7342546A FR 7342546 A FR7342546 A FR 7342546A FR 2209560 A1 FR2209560 A1 FR 2209560A1
Authority
FR
France
Prior art keywords
alkyl
ethylenediamine
ring
piperidino
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7342546A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of FR2209560A1 publication Critical patent/FR2209560A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7342546A 1972-12-07 1973-11-29 N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin Withdrawn FR2209560A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1044372 1972-12-07

Publications (1)

Publication Number Publication Date
FR2209560A1 true FR2209560A1 (en) 1974-07-05

Family

ID=3622380

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7342546A Withdrawn FR2209560A1 (en) 1972-12-07 1973-11-29 N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin

Country Status (7)

Country Link
JP (1) JPS4993334A (fr)
BE (1) BE808337A (fr)
DD (1) DD109632A5 (fr)
DE (1) DE2360545A1 (fr)
ES (2) ES421159A1 (fr)
FR (1) FR2209560A1 (fr)
NL (1) NL7316714A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2474031A1 (fr) * 1980-01-21 1981-07-24 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyle piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
FR2497512A2 (fr) * 1981-01-07 1982-07-09 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
EP0064878A1 (fr) * 1981-05-08 1982-11-17 Otsuka Pharmaceutical Co., Ltd. Dérivés d'aniline, procédé pour leur préparation et compositions cardiotoniques les contenant
EP0395446A2 (fr) * 1989-04-28 1990-10-31 Sankyo Company Limited Dérivés N-acryloylpipérazine, leur préparation et leur usage comme PAF-antagonistes

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582371D1 (de) * 1984-07-06 1991-05-08 Otsuka Pharma Co Ltd Oxindolverbindungen, diese enthaltende zusammensetzungen sowie verfahren zur herstellung derselben.
US4623651A (en) * 1985-10-15 1986-11-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic heterocyclocarbonyl- and acetyl-thiazolones
JP2573195B2 (ja) * 1986-09-30 1997-01-22 エーザイ株式会社 環状アミン誘導体
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823775D0 (en) * 1988-10-11 1988-11-16 Scras New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8908587D0 (en) * 1989-04-15 1989-06-01 Scras Societe De Conseils De R New 2-substituted n,n'-ditrimethoxybenzoyl piperazines
US6214994B1 (en) 1997-04-21 2001-04-10 Molecular Geriatrics Corporation Certain substituted 1-aryl-3-piperazin-1′-yl propanones
US5693804A (en) * 1994-11-17 1997-12-02 Molecular Geriatrics Corporation Substituted 1-aryl-3-piperazin-1'-yl propanones

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2474031A1 (fr) * 1980-01-21 1981-07-24 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyle piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
FR2497512A2 (fr) * 1981-01-07 1982-07-09 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
EP0064878A1 (fr) * 1981-05-08 1982-11-17 Otsuka Pharmaceutical Co., Ltd. Dérivés d'aniline, procédé pour leur préparation et compositions cardiotoniques les contenant
EP0395446A2 (fr) * 1989-04-28 1990-10-31 Sankyo Company Limited Dérivés N-acryloylpipérazine, leur préparation et leur usage comme PAF-antagonistes
EP0395446A3 (fr) * 1989-04-28 1991-05-29 Sankyo Company Limited Dérivés N-acryloylpipérazine, leur préparation et leur usage comme PAF-antagonistes

Also Published As

Publication number Publication date
ES421160A1 (es) 1976-04-16
NL7316714A (fr) 1974-06-11
JPS4993334A (fr) 1974-09-05
BE808337A (fr) 1974-06-06
DD109632A5 (fr) 1974-11-12
ES421159A1 (es) 1976-04-16
DE2360545A1 (de) 1974-06-12

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Legal Events

Date Code Title Description
RE Withdrawal of published application