FR2194434A1 - Bis piperazino-androstanes - as muscle relaxants - Google Patents
Bis piperazino-androstanes - as muscle relaxantsInfo
- Publication number
- FR2194434A1 FR2194434A1 FR7327718A FR7327718A FR2194434A1 FR 2194434 A1 FR2194434 A1 FR 2194434A1 FR 7327718 A FR7327718 A FR 7327718A FR 7327718 A FR7327718 A FR 7327718A FR 2194434 A1 FR2194434 A1 FR 2194434A1
- Authority
- FR
- France
- Prior art keywords
- alpha
- androstanes
- piperazino
- bis
- muscle relaxants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KRDFGGOCYYYSSP-FZVVDOERSA-N 1-[(5R,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-15-yl]piperazine Chemical class N1(CCNCC1)C1[C@@H]2[C@](CC1)(C)CC[C@H]1[C@H]2CC[C@H]2CCCC[C@]12C KRDFGGOCYYYSSP-FZVVDOERSA-N 0.000 title 1
- 229940035363 muscle relaxants Drugs 0.000 title 1
- 239000003158 myorelaxant agent Substances 0.000 title 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000005905 mesyloxy group Chemical group 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 125000005424 tosyloxy group Chemical group S(=O)(=O)(C1=CC=C(C)C=C1)O* 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI471A HU165600B (enrdf_load_stackoverflow) | 1972-07-27 | 1972-07-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2194434A1 true FR2194434A1 (en) | 1974-03-01 |
| FR2194434B1 FR2194434B1 (enrdf_load_stackoverflow) | 1977-04-15 |
Family
ID=11000894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7327718A Granted FR2194434A1 (en) | 1972-07-27 | 1973-07-27 | Bis piperazino-androstanes - as muscle relaxants |
Country Status (17)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2318174A1 (fr) * | 1975-07-15 | 1977-02-11 | Richter Gedeon Vegyeszet | Diepoxy-androstanes et leur preparation |
| EP0246469A1 (de) * | 1986-05-03 | 1987-11-25 | Hoechst Aktiengesellschaft | Verfahren zur Verkapselung von biologisch aktivem Material |
| EP0608495A3 (en) * | 1992-11-02 | 1995-12-20 | Zoltan Tuba | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same. |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU172521B (hu) * | 1975-08-01 | 1978-09-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh proizvodnykh triamino-androstana i chetvertichnykh solejj |
| WO2006038047A1 (en) * | 2004-10-07 | 2006-04-13 | Richter Gedeon Vegyészeti Gyár Rt. | Environment-friend process for the synthesis of quaternary ammonio-steroιds |
-
1972
- 1972-07-27 HU HURI471A patent/HU165600B/hu unknown
-
1973
- 1973-06-26 IL IL42600A patent/IL42600A/en unknown
- 1973-07-04 AT AT589173A patent/AT327414B/de not_active IP Right Cessation
- 1973-07-23 CS CS735251A patent/CS193475B2/cs unknown
- 1973-07-24 SE SE7310295A patent/SE398506B/xx unknown
- 1973-07-24 DD DD172557A patent/DD106036A5/xx unknown
- 1973-07-25 PL PL1973164288A patent/PL89360B1/pl unknown
- 1973-07-25 PL PL1973183828A patent/PL92579B1/pl unknown
- 1973-07-26 RO RO7375603A patent/RO71515A/ro unknown
- 1973-07-26 DK DK412473*A patent/DK132662C/da active Protection Beyond IP Right Term
- 1973-07-26 SU SU7301953816A patent/SU582768A3/ru active
- 1973-07-26 NL NLAANVRAGE7310389,A patent/NL174945C/xx active Protection Beyond IP Right Term
- 1973-07-26 CA CA177,348A patent/CA1023343A/en not_active Expired
- 1973-07-26 DE DE2337882A patent/DE2337882C3/de not_active Expired
- 1973-07-27 YU YU2052/73A patent/YU35776B/xx unknown
- 1973-07-27 FR FR7327718A patent/FR2194434A1/fr active Granted
- 1973-07-27 JP JP48084795A patent/JPS5231922B2/ja not_active Expired
- 1973-07-27 BE BE133964A patent/BE802903A/xx active Protection Beyond IP Right Term
-
1993
- 1993-06-24 NL NL930088C patent/NL930088I2/nl unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2318174A1 (fr) * | 1975-07-15 | 1977-02-11 | Richter Gedeon Vegyeszet | Diepoxy-androstanes et leur preparation |
| EP0246469A1 (de) * | 1986-05-03 | 1987-11-25 | Hoechst Aktiengesellschaft | Verfahren zur Verkapselung von biologisch aktivem Material |
| EP0608495A3 (en) * | 1992-11-02 | 1995-12-20 | Zoltan Tuba | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same. |
| US5591735A (en) * | 1992-11-02 | 1997-01-07 | Marvishi Pharmaceutical Co., Ltd. | Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same |
Also Published As
| Publication number | Publication date |
|---|---|
| DD106036A5 (enrdf_load_stackoverflow) | 1974-05-20 |
| SE398506B (sv) | 1977-12-27 |
| NL930088I2 (nl) | 1994-02-16 |
| AU5750973A (en) | 1975-01-09 |
| JPS5231922B2 (enrdf_load_stackoverflow) | 1977-08-18 |
| YU35776B (en) | 1981-06-30 |
| DE2337882C3 (de) | 1979-02-15 |
| YU205273A (en) | 1980-10-31 |
| PL89360B1 (en) | 1976-11-30 |
| IL42600A (en) | 1977-05-31 |
| SU582768A3 (ru) | 1977-11-30 |
| CA1023343A (en) | 1977-12-27 |
| NL174945C (nl) | 1984-09-03 |
| DK132662C (da) | 1976-08-02 |
| CS193475B2 (en) | 1979-10-31 |
| HU165600B (enrdf_load_stackoverflow) | 1974-09-28 |
| NL7310389A (enrdf_load_stackoverflow) | 1974-01-29 |
| AT327414B (de) | 1976-01-26 |
| RO71515A (ro) | 1982-10-26 |
| DK132662B (da) | 1976-01-19 |
| PL92579B1 (en) | 1977-04-30 |
| DE2337882A1 (de) | 1974-02-07 |
| JPS4992081A (enrdf_load_stackoverflow) | 1974-09-03 |
| DE2337882B2 (de) | 1978-06-08 |
| FR2194434B1 (enrdf_load_stackoverflow) | 1977-04-15 |
| NL930088I1 (nl) | 1993-10-01 |
| ATA589173A (de) | 1975-04-15 |
| NL174945B (nl) | 1984-04-02 |
| BE802903A (fr) | 1973-11-16 |
| IL42600A0 (en) | 1973-08-29 |
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