FR2190413A2 - Stable,pyrogen-free urokinase prepns - from human urine - Google Patents

Stable,pyrogen-free urokinase prepns - from human urine

Info

Publication number
FR2190413A2
FR2190413A2 FR7223868A FR7223868A FR2190413A2 FR 2190413 A2 FR2190413 A2 FR 2190413A2 FR 7223868 A FR7223868 A FR 7223868A FR 7223868 A FR7223868 A FR 7223868A FR 2190413 A2 FR2190413 A2 FR 2190413A2
Authority
FR
France
Prior art keywords
hos
urokinase
conductivity
prepns
pyrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7223868A
Other languages
English (en)
French (fr)
Other versions
FR2190413B2 (US20070031759A1-20070208-C00007.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Choay SA
Original Assignee
Choay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE789189D priority Critical patent/BE789189A/xx
Application filed by Choay SA filed Critical Choay SA
Priority to FR7223868A priority patent/FR2190413A2/fr
Priority to SE7212220A priority patent/SE405806B/sv
Priority to NL7212891A priority patent/NL7212891A/xx
Priority to JP9561172A priority patent/JPS5718465B2/ja
Priority to CH1384072A priority patent/CH560050A5/xx
Priority to CH1715974A priority patent/CH604726A5/xx
Priority to CA152,328A priority patent/CA986013A/en
Priority to GB1550275A priority patent/GB1411422A/en
Priority to GB4400372A priority patent/GB1411421A/en
Priority to DK470672A priority patent/DK133130C/da
Priority to ES406980A priority patent/ES406980A1/es
Priority to DE2246969A priority patent/DE2246969C2/de
Priority to US292139A priority patent/US3926727A/en
Priority to IN2122/CAL/1973A priority patent/IN141112B/en
Publication of FR2190413A2 publication Critical patent/FR2190413A2/fr
Application granted granted Critical
Publication of FR2190413B2 publication Critical patent/FR2190413B2/fr
Priority to ES440244A priority patent/ES440244A1/es
Priority to US05/629,076 priority patent/US4029767A/en
Priority to US05/628,968 priority patent/US4106992A/en
Priority to SE7514792A priority patent/SE7514792L/xx
Priority to ES455975A priority patent/ES455975A1/es
Priority to NLAANVRAGE8300232,A priority patent/NL183495C/xx
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR7223868A 1971-09-24 1972-06-30 Stable,pyrogen-free urokinase prepns - from human urine Granted FR2190413A2 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
BE789189D BE789189A (fr) 1971-09-24 Perfectionnements aux procedes de preparation, de depyrogenation et de stabilisation de l'urokinase et compositions obtenues
FR7223868A FR2190413A2 (en) 1972-06-30 1972-06-30 Stable,pyrogen-free urokinase prepns - from human urine
SE7212220A SE405806B (sv) 1971-09-24 1972-09-21 Forfarande for framstellning av urokinas-heparinkomplex
DK470672A DK133130C (da) 1971-09-24 1972-09-22 Fremgangsmade til fremstilling af urokinaseheparinat
JP9561172A JPS5718465B2 (US20070031759A1-20070208-C00007.png) 1971-09-24 1972-09-22
CH1384072A CH560050A5 (US20070031759A1-20070208-C00007.png) 1971-09-24 1972-09-22
CH1715974A CH604726A5 (US20070031759A1-20070208-C00007.png) 1971-09-24 1972-09-22
CA152,328A CA986013A (en) 1971-09-24 1972-09-22 Methods for preparing depyrogenising and stabilising urokinase and compositions obtained thereby
GB1550275A GB1411422A (en) 1971-09-24 1972-09-22 Methods for purifying urokinase preparations
GB4400372A GB1411421A (en) 1971-09-24 1972-09-22 Urokinaseheparin complex
NL7212891A NL7212891A (US20070031759A1-20070208-C00007.png) 1971-09-24 1972-09-22
ES406980A ES406980A1 (es) 1971-09-24 1972-09-23 Un procedimiento de fabricacion de heparinato de uroquina- sa.
US292139A US3926727A (en) 1971-09-24 1972-09-25 Urokinase preparations
DE2246969A DE2246969C2 (de) 1971-09-24 1972-09-25 Urokinase-Heparinat und dieses enthaltende Arzneimittel
IN2122/CAL/1973A IN141112B (US20070031759A1-20070208-C00007.png) 1971-09-24 1973-09-17
ES440244A ES440244A1 (es) 1971-09-24 1975-08-14 Procedimiento de purificacion de una solucion de uroquinasa mezclada con proteinas extranas y sustancias pirogenas.
US05/629,076 US4029767A (en) 1971-09-24 1975-11-05 Pharmaceutical compositions of stable urokinase-heparin complexes and methods for use thereof
US05/628,968 US4106992A (en) 1971-09-24 1975-11-05 Purification of urokinase
SE7514792A SE7514792L (sv) 1971-09-24 1975-12-30 Forfarande for framstellning av urokinas
ES455975A ES455975A1 (es) 1971-09-24 1977-02-16 Un procedimiento de obtencion de una disolucion enriquecida en uroquinasa.
NLAANVRAGE8300232,A NL183495C (nl) 1971-09-24 1983-01-21 Werkwijze voor het bereiden van een urokinase-perfusie-oplossing alsmede werkwijze voor het bereiden van een voor dergelijke toepassing geschikt urokinase-heparinaat.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7223868A FR2190413A2 (en) 1972-06-30 1972-06-30 Stable,pyrogen-free urokinase prepns - from human urine

Publications (2)

Publication Number Publication Date
FR2190413A2 true FR2190413A2 (en) 1974-02-01
FR2190413B2 FR2190413B2 (US20070031759A1-20070208-C00007.png) 1975-06-20

Family

ID=9101199

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7223868A Granted FR2190413A2 (en) 1971-09-24 1972-06-30 Stable,pyrogen-free urokinase prepns - from human urine

Country Status (1)

Country Link
FR (1) FR2190413A2 (US20070031759A1-20070208-C00007.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2291983A1 (fr) * 1974-11-20 1976-06-18 Abbott Lab Purification de l'urokinase
FR2395275A1 (fr) * 1977-03-10 1979-01-19 Sumitomo Chemical Co Procede de purification de l'urokinase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2291983A1 (fr) * 1974-11-20 1976-06-18 Abbott Lab Purification de l'urokinase
FR2395275A1 (fr) * 1977-03-10 1979-01-19 Sumitomo Chemical Co Procede de purification de l'urokinase

Also Published As

Publication number Publication date
FR2190413B2 (US20070031759A1-20070208-C00007.png) 1975-06-20

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