FR2189020A1 - Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains - Google Patents
Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strainsInfo
- Publication number
- FR2189020A1 FR2189020A1 FR7222121A FR7222121A FR2189020A1 FR 2189020 A1 FR2189020 A1 FR 2189020A1 FR 7222121 A FR7222121 A FR 7222121A FR 7222121 A FR7222121 A FR 7222121A FR 2189020 A1 FR2189020 A1 FR 2189020A1
- Authority
- FR
- France
- Prior art keywords
- maaf
- water
- canetti
- prepn
- bcg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 229960001438 immunostimulant agent Drugs 0.000 title 1
- 239000003022 immunostimulating agent Substances 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 abstract 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 abstract 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222121A FR2189020A1 (en) | 1972-06-20 | 1972-06-20 | Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222121A FR2189020A1 (en) | 1972-06-20 | 1972-06-20 | Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2189020A1 true FR2189020A1 (en) | 1974-01-25 |
| FR2189020B1 FR2189020B1 (enExample) | 1975-06-20 |
Family
ID=9100446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7222121A Granted FR2189020A1 (en) | 1972-06-20 | 1972-06-20 | Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2189020A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2399845A2 (fr) * | 1977-08-09 | 1979-03-09 | Azuma Ichiro | Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2020758A1 (en) * | 1968-10-15 | 1970-07-17 | Merieux Charles | Immunity stimulation against bacterial infec- - tions |
| US3529057A (en) * | 1964-08-14 | 1970-09-15 | Takeda Chemical Industries Ltd | Purified periodic acid-oxidized mucopeptide of mycobacteria cell walls constituting a vaccine enhancing nonspecific host resistance against pathogenic bacterial infections |
-
1972
- 1972-06-20 FR FR7222121A patent/FR2189020A1/fr active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3529057A (en) * | 1964-08-14 | 1970-09-15 | Takeda Chemical Industries Ltd | Purified periodic acid-oxidized mucopeptide of mycobacteria cell walls constituting a vaccine enhancing nonspecific host resistance against pathogenic bacterial infections |
| FR2020758A1 (en) * | 1968-10-15 | 1970-07-17 | Merieux Charles | Immunity stimulation against bacterial infec- - tions |
Non-Patent Citations (1)
| Title |
|---|
| CHEMICAL ABSTRACTS, VOLUME 76, REFERENCE 137850R, 1972 CITE OSAKA DAIGAKU SHIGAKU ZASSHI 1970, 15 1 , 111-40.) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2399845A2 (fr) * | 1977-08-09 | 1979-03-09 | Azuma Ichiro | Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2189020B1 (enExample) | 1975-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |