FR2399845A2 - Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation - Google Patents

Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation

Info

Publication number
FR2399845A2
FR2399845A2 FR7823321A FR7823321A FR2399845A2 FR 2399845 A2 FR2399845 A2 FR 2399845A2 FR 7823321 A FR7823321 A FR 7823321A FR 7823321 A FR7823321 A FR 7823321A FR 2399845 A2 FR2399845 A2 FR 2399845A2
Authority
FR
France
Prior art keywords
glycolipid
immunotherapy
preparing
active ingredient
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR7823321A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2399845A2 publication Critical patent/FR2399845A2/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne l'industrie pharmaceutique. Compositions pharmaceutiques contenant comme ingrédients actifs : 1 degrés un glycolipide (dont le résidu sucre appartient au groupe des fructose, sucrose et glucose), et 2 degrés un antigène de tumeur provenant de la paroi cellulaire d'un micro-organisme, avec un excipient pharmaceutique. Application en immunothérapie, particulièrement contre la leucemie, le sarcome et les tumeurs mélaniques.
FR7823321A 1977-08-09 1978-08-08 Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation Pending FR2399845A2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9540477A JPS5428830A (en) 1977-08-09 1977-08-09 Immunological treating agent of tumor containing glycolipid as effective component

Publications (1)

Publication Number Publication Date
FR2399845A2 true FR2399845A2 (fr) 1979-03-09

Family

ID=14136723

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7823321A Pending FR2399845A2 (fr) 1977-08-09 1978-08-08 Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation

Country Status (3)

Country Link
JP (1) JPS5428830A (fr)
FR (1) FR2399845A2 (fr)
GB (1) GB1596516A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012083A1 (fr) * 1978-12-01 1980-06-11 Merck & Co. Inc. Adjuvant immunologique, procédé de préparation et vaccin contenant cet adjuvant
FR2542012A1 (fr) * 1983-03-04 1984-09-07 Maruyama Chisato Lipopolysaccharide et procede pour sa preparation
EP0144894A2 (fr) * 1983-12-07 1985-06-19 Bayer Ag Application thérapeutique de O-acyl glycosides substitués

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2184531A1 (fr) * 1972-05-19 1973-12-28 Anvar
FR2189020A1 (en) * 1972-06-20 1974-01-25 Anvar Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains
FR2275224A1 (fr) * 1974-06-20 1976-01-16 Anvar Fractions mycobacteriennes utilisables comme agent anti-infectieux, et procede pour leur preparation
FR2355506A1 (fr) * 1976-06-25 1978-01-20 Azuma Ichiro Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation
FR2374911A1 (fr) * 1976-12-21 1978-07-21 Fabre Sa Pierre Adjuvants d'immunite non specifique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR7410683A (pt) * 1974-12-19 1976-07-27 Hirano I Aperfeicoamento em camara de compensacao
JPS5129291A (en) * 1974-09-02 1976-03-12 Kyowa Hakko Kogyo Kk Hatsukohonyorukato oyobi shotonoshibosanesuteru no seizoho
JPS58183863A (ja) * 1982-04-22 1983-10-27 Nippon Denso Co Ltd 内燃機関用無接点点火装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2184531A1 (fr) * 1972-05-19 1973-12-28 Anvar
FR2189020A1 (en) * 1972-06-20 1974-01-25 Anvar Water-soluble lipid-free mycobacterial fraction - immuno stimulant and anti tumour agent prepn. from BCG or canetti strains
FR2275224A1 (fr) * 1974-06-20 1976-01-16 Anvar Fractions mycobacteriennes utilisables comme agent anti-infectieux, et procede pour leur preparation
FR2355506A1 (fr) * 1976-06-25 1978-01-20 Azuma Ichiro Adjuvant d'immunotherapie contenant un glycolipide comme ingredient actif et son procede de preparation
FR2374911A1 (fr) * 1976-12-21 1978-07-21 Fabre Sa Pierre Adjuvants d'immunite non specifique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/75 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012083A1 (fr) * 1978-12-01 1980-06-11 Merck & Co. Inc. Adjuvant immunologique, procédé de préparation et vaccin contenant cet adjuvant
FR2542012A1 (fr) * 1983-03-04 1984-09-07 Maruyama Chisato Lipopolysaccharide et procede pour sa preparation
EP0144894A2 (fr) * 1983-12-07 1985-06-19 Bayer Ag Application thérapeutique de O-acyl glycosides substitués
EP0144894A3 (fr) * 1983-12-07 1989-08-23 Bayer Ag Application thérapeutique de O-acyl glycosides substitués

Also Published As

Publication number Publication date
JPS5428830A (en) 1979-03-03
GB1596516A (en) 1981-08-26

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