FR2172853A1 - Topical antiviral compositions - contg 2-fluorenonyl-glyoxal sodium bisulphite compound - Google Patents
Topical antiviral compositions - contg 2-fluorenonyl-glyoxal sodium bisulphite compoundInfo
- Publication number
- FR2172853A1 FR2172853A1 FR7206288A FR7206288A FR2172853A1 FR 2172853 A1 FR2172853 A1 FR 2172853A1 FR 7206288 A FR7206288 A FR 7206288A FR 7206288 A FR7206288 A FR 7206288A FR 2172853 A1 FR2172853 A1 FR 2172853A1
- Authority
- FR
- France
- Prior art keywords
- degrees
- fluorenone
- give
- resulting
- fluorenonylglyoxal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 2-fluorenonyl-glyoxal sodium bisulphite compound Chemical class 0.000 title 1
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 4
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 4
- NIHNNTQXNPWCJQ-UHFFFAOYSA-N fluorene Chemical compound C1=CC=C2CC3=CC=CC=C3C2=C1 NIHNNTQXNPWCJQ-UHFFFAOYSA-N 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 239000003960 organic solvent Substances 0.000 abstract 3
- LYDODFACTLGGNT-UHFFFAOYSA-N 2-oxo-2-(1-oxofluoren-2-yl)acetaldehyde Chemical compound C1=CC=C2C3=CC=C(C(=O)C=O)C(=O)C3=CC2=C1 LYDODFACTLGGNT-UHFFFAOYSA-N 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- KRVSOGSZCMJSLX-UHFFFAOYSA-L chromic acid Chemical class O[Cr](O)(=O)=O KRVSOGSZCMJSLX-UHFFFAOYSA-L 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- IBASEVZORZFIIH-UHFFFAOYSA-N 1-(9h-fluoren-2-yl)ethanone Chemical compound C1=CC=C2C3=CC=C(C(=O)C)C=C3CC2=C1 IBASEVZORZFIIH-UHFFFAOYSA-N 0.000 abstract 1
- KZCVYXMFPCPVRS-UHFFFAOYSA-N 2,2-dichloro-1-(9H-fluoren-2-yl)ethanone Chemical compound ClC(C(=O)C1=CC=2CC3=CC=CC=C3C2C=C1)Cl KZCVYXMFPCPVRS-UHFFFAOYSA-N 0.000 abstract 1
- ABZXCLKGHHABSF-UHFFFAOYSA-N 2-(2,2-dibromoacetyl)fluoren-1-one Chemical compound BrC(C(=O)C=1C(C2=CC3=CC=CC=C3C2=CC1)=O)Br ABZXCLKGHHABSF-UHFFFAOYSA-N 0.000 abstract 1
- DEDUYYWSOQFJFL-UHFFFAOYSA-N 2-(2,2-dichloroacetyl)fluoren-1-one Chemical compound ClC(C(=O)C=1C(C2=CC3=CC=CC=C3C2=CC1)=O)Cl DEDUYYWSOQFJFL-UHFFFAOYSA-N 0.000 abstract 1
- ARUJRNPQACJMAX-UHFFFAOYSA-N 2-(2,2-dimorpholin-4-ylacetyl)fluoren-1-one Chemical compound O1CCN(CC1)C(C(=O)C=1C(C2=CC3=CC=CC=C3C2=CC1)=O)N1CCOCC1 ARUJRNPQACJMAX-UHFFFAOYSA-N 0.000 abstract 1
- CWXNCOWTIATRLD-UHFFFAOYSA-N 2-acetylfluoren-9-one Chemical compound C1=CC=C2C(=O)C3=CC(C(=O)C)=CC=C3C2=C1 CWXNCOWTIATRLD-UHFFFAOYSA-N 0.000 abstract 1
- LBRGEQVNFACNTC-UHFFFAOYSA-N 2-oxo-2-(1-oxofluoren-2-yl)acetaldehyde hydrate Chemical compound O.C1=CC=C2C3=CC=C(C(=O)C=O)C(=O)C3=CC2=C1 LBRGEQVNFACNTC-UHFFFAOYSA-N 0.000 abstract 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 abstract 1
- 229910019213 POCl3 Inorganic materials 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- FBCCMZVIWNDFMO-UHFFFAOYSA-N dichloroacetyl chloride Chemical compound ClC(Cl)C(Cl)=O FBCCMZVIWNDFMO-UHFFFAOYSA-N 0.000 abstract 1
- AWJWCTOOIBYHON-UHFFFAOYSA-N furo[3,4-b]pyrazine-5,7-dione Chemical compound C1=CN=C2C(=O)OC(=O)C2=N1 AWJWCTOOIBYHON-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000003883 ointment base Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000008063 pharmaceutical solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7206288A FR2172853A1 (en) | 1972-02-24 | 1972-02-24 | Topical antiviral compositions - contg 2-fluorenonyl-glyoxal sodium bisulphite compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7206288A FR2172853A1 (en) | 1972-02-24 | 1972-02-24 | Topical antiviral compositions - contg 2-fluorenonyl-glyoxal sodium bisulphite compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2172853A1 true FR2172853A1 (en) | 1973-10-05 |
| FR2172853B1 FR2172853B1 (cg-RX-API-DMAC7.html) | 1975-03-14 |
Family
ID=9094059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7206288A Granted FR2172853A1 (en) | 1972-02-24 | 1972-02-24 | Topical antiviral compositions - contg 2-fluorenonyl-glyoxal sodium bisulphite compound |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2172853A1 (cg-RX-API-DMAC7.html) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3146259A (en) * | 1961-06-13 | 1964-08-25 | Smith Kline French Lab | Fluorenyl bisglyoxal derivatives |
-
1972
- 1972-02-24 FR FR7206288A patent/FR2172853A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3146259A (en) * | 1961-06-13 | 1964-08-25 | Smith Kline French Lab | Fluorenyl bisglyoxal derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2172853B1 (cg-RX-API-DMAC7.html) | 1975-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |