FR2168947A1 - Amino gp contg cyclopropane derivs - with pharmacological props - Google Patents

Amino gp contg cyclopropane derivs - with pharmacological props

Info

Publication number
FR2168947A1
FR2168947A1 FR7202753A FR7202753A FR2168947A1 FR 2168947 A1 FR2168947 A1 FR 2168947A1 FR 7202753 A FR7202753 A FR 7202753A FR 7202753 A FR7202753 A FR 7202753A FR 2168947 A1 FR2168947 A1 FR 2168947A1
Authority
FR
France
Prior art keywords
alkyl
substd
derivs
cyclopropane
contg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7202753A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Priority to FR7202753A priority Critical patent/FR2168947A1/en
Publication of FR2168947A1 publication Critical patent/FR2168947A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Title cpds. are of formula:- (where R1 and R2 are alkyl or aralkyl, or form, together with the N atom to which they are linked, a morpholino, piperidino or substd. piperidine radical of formula: (where Z1 is OH, (mono or di-alkyl substd.) carbamyl, acyl or cyano gp.; Z2 is a piperidine or phenyl gp. opt. substd. by halogen, trifluoromethyl, or (where Y1 = phenyl and Y2 = acyl, or together with the linking N form an oxo-2-benzimidazoline gp.); R3 is H, alkyl, or aryl, opt. substd. by >=1 alkyl; R4 is H or acyl; R5 is alkyl or aryl, or their acid addition salts. The derivs. are formed by the reaction of a ketone with a metal deriv. of R3 and then esterifying the alcohol formed.
FR7202753A 1972-01-27 1972-01-27 Amino gp contg cyclopropane derivs - with pharmacological props Withdrawn FR2168947A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7202753A FR2168947A1 (en) 1972-01-27 1972-01-27 Amino gp contg cyclopropane derivs - with pharmacological props

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7202753A FR2168947A1 (en) 1972-01-27 1972-01-27 Amino gp contg cyclopropane derivs - with pharmacological props

Publications (1)

Publication Number Publication Date
FR2168947A1 true FR2168947A1 (en) 1973-09-07

Family

ID=9092553

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7202753A Withdrawn FR2168947A1 (en) 1972-01-27 1972-01-27 Amino gp contg cyclopropane derivs - with pharmacological props

Country Status (1)

Country Link
FR (1) FR2168947A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1254892A2 (en) * 2001-04-23 2002-11-06 Daicel Chemical Industries, Ltd. N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1254892A2 (en) * 2001-04-23 2002-11-06 Daicel Chemical Industries, Ltd. N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor
EP1254892A3 (en) * 2001-04-23 2002-12-11 Daicel Chemical Industries, Ltd. N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor
US6710210B2 (en) 2001-04-23 2004-03-23 Daicel Chemical Industries, Ltd. N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor

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Legal Events

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