FR2153206A2 - Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics - Google Patents

Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics

Info

Publication number
FR2153206A2
FR2153206A2 FR7134517A FR7134517A FR2153206A2 FR 2153206 A2 FR2153206 A2 FR 2153206A2 FR 7134517 A FR7134517 A FR 7134517A FR 7134517 A FR7134517 A FR 7134517A FR 2153206 A2 FR2153206 A2 FR 2153206A2
Authority
FR
France
Prior art keywords
lower alkyl
mono
alkyl
opt
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7134517A
Other languages
French (fr)
Other versions
FR2153206B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to FR7134517A priority Critical patent/FR2153206A2/en
Priority to BE773062A priority patent/BE773062R/en
Priority to DE2147857A priority patent/DE2147857C2/en
Publication of FR2153206A2 publication Critical patent/FR2153206A2/en
Application granted granted Critical
Publication of FR2153206B2 publication Critical patent/FR2153206B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel title cpds are the dl- and l-isomers of cpds. of formula: (in which R1 and R2 are H, 3-10 C alkyl, 2-8 C alkenyl, 3-7 C cycloalkyl, lower hydroxyalklyl, lower alkanoyloxy-lower alkyl, lower alkoxy-lower alkyl, opt. substd. benzyl, opt. substd. phenylethyl, mono- or di-nitrophenyl, 2- or 4-pyridyl, 2- or 4-pyrimidyl, 2-thiazolyl, pyridylmethyl, furfuryl, tetrahydrofurfuryl or R5CO (where R5 is H, 1-9 C alkyl, 2-7 C alkenyl, 3-7 C cycloalkyl, 1-6 C haloalkyl, 1-6 C aminoalkyl, mono- or di- lower alkyl-amino-lower alkyl, piperidino-lower alkyl, pyrrolidino-lower alkyl, morpholino-lower alkyl, lower alkoxy-lower alkyl, opt. substd. phenyl, furfuryl, tetrahydrofurfuryl, naphthyl, 1-8 C alkoxy, amino, mono- or di- lower alkylamino, piperidino, pyrrolidino or morpholino) or -NR1R2 is piperidino, pyrrolidino, morpholino or (lower alkyl)2NCH = N- and R3 and R4 are H, halogen, or NO2, but when Re3 and R4 are both H, only one of R1 and R2 may be H; the opt. substs. being selected from mono-, di-, or tri-halo, mono- or di-NO2, mono-, di or tri- lower alkyl, or mono-, di- or tri- lower alkoxy; and represents a single or double bond) and are claimed together with their pharmaceutically acceptable salts.
FR7134517A 1971-09-24 1971-09-24 Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics Granted FR2153206A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7134517A FR2153206A2 (en) 1971-09-24 1971-09-24 Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics
BE773062A BE773062R (en) 1971-09-24 1971-09-24 NEW PHENYLTETRAHYDROTHIAZOLES, THEIR PREPARATION AND THEIR THERAPEUTIC USES
DE2147857A DE2147857C2 (en) 1971-09-24 1971-09-24 Substituted 6-phenyl-imidazo [2,1-b] -thiazoles, process for their preparation and anthelmintic agents containing them

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7134517A FR2153206A2 (en) 1971-09-24 1971-09-24 Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics
BE773062A BE773062R (en) 1971-09-24 1971-09-24 NEW PHENYLTETRAHYDROTHIAZOLES, THEIR PREPARATION AND THEIR THERAPEUTIC USES
DE2147857A DE2147857C2 (en) 1971-09-24 1971-09-24 Substituted 6-phenyl-imidazo [2,1-b] -thiazoles, process for their preparation and anthelmintic agents containing them

Publications (2)

Publication Number Publication Date
FR2153206A2 true FR2153206A2 (en) 1973-05-04
FR2153206B2 FR2153206B2 (en) 1975-10-31

Family

ID=27159388

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7134517A Granted FR2153206A2 (en) 1971-09-24 1971-09-24 Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics

Country Status (3)

Country Link
BE (1) BE773062R (en)
DE (1) DE2147857C2 (en)
FR (1) FR2153206A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018932A (en) 1975-11-03 1977-04-19 American Cyanamid Company Anthelmintic pour-on formulations for topical use on domestic and farm animals
GB1516938A (en) * 1976-05-01 1978-07-05 Pfizer Ltd Halopyridylamides of m-aminotetramisole and their use as anthelmintics
EP0041322A1 (en) * 1980-05-30 1981-12-09 Beecham Group Plc m-Pyrazolylamido tetramisole derivatives, compositions thereof, processes for production of such compounds and compositions and their use in treating helminthiasis
GR74993B (en) * 1980-08-16 1984-07-12 Beecham Group Ltd

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3463786A (en) * 1967-12-19 1969-08-26 American Cyanamid Co Method of resolving dl 6 - phenyl - 2,3,5,6-tetrahydroimidazo(2,1-b) - thiazole and novel compounds resulting therefrom

Also Published As

Publication number Publication date
FR2153206B2 (en) 1975-10-31
BE773062R (en) 1972-03-24
DE2147857C2 (en) 1985-09-12
DE2147857A1 (en) 1973-05-30

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