FR2153206A2 - Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics - Google Patents
Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelminticsInfo
- Publication number
- FR2153206A2 FR2153206A2 FR7134517A FR7134517A FR2153206A2 FR 2153206 A2 FR2153206 A2 FR 2153206A2 FR 7134517 A FR7134517 A FR 7134517A FR 7134517 A FR7134517 A FR 7134517A FR 2153206 A2 FR2153206 A2 FR 2153206A2
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- mono
- alkyl
- opt
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel title cpds are the dl- and l-isomers of cpds. of formula: (in which R1 and R2 are H, 3-10 C alkyl, 2-8 C alkenyl, 3-7 C cycloalkyl, lower hydroxyalklyl, lower alkanoyloxy-lower alkyl, lower alkoxy-lower alkyl, opt. substd. benzyl, opt. substd. phenylethyl, mono- or di-nitrophenyl, 2- or 4-pyridyl, 2- or 4-pyrimidyl, 2-thiazolyl, pyridylmethyl, furfuryl, tetrahydrofurfuryl or R5CO (where R5 is H, 1-9 C alkyl, 2-7 C alkenyl, 3-7 C cycloalkyl, 1-6 C haloalkyl, 1-6 C aminoalkyl, mono- or di- lower alkyl-amino-lower alkyl, piperidino-lower alkyl, pyrrolidino-lower alkyl, morpholino-lower alkyl, lower alkoxy-lower alkyl, opt. substd. phenyl, furfuryl, tetrahydrofurfuryl, naphthyl, 1-8 C alkoxy, amino, mono- or di- lower alkylamino, piperidino, pyrrolidino or morpholino) or -NR1R2 is piperidino, pyrrolidino, morpholino or (lower alkyl)2NCH = N- and R3 and R4 are H, halogen, or NO2, but when Re3 and R4 are both H, only one of R1 and R2 may be H; the opt. substs. being selected from mono-, di-, or tri-halo, mono- or di-NO2, mono-, di or tri- lower alkyl, or mono-, di- or tri- lower alkoxy; and represents a single or double bond) and are claimed together with their pharmaceutically acceptable salts.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7134517A FR2153206A2 (en) | 1971-09-24 | 1971-09-24 | Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics |
BE773062A BE773062R (en) | 1971-09-24 | 1971-09-24 | NEW PHENYLTETRAHYDROTHIAZOLES, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
DE2147857A DE2147857C2 (en) | 1971-09-24 | 1971-09-24 | Substituted 6-phenyl-imidazo [2,1-b] -thiazoles, process for their preparation and anthelmintic agents containing them |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7134517A FR2153206A2 (en) | 1971-09-24 | 1971-09-24 | Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics |
BE773062A BE773062R (en) | 1971-09-24 | 1971-09-24 | NEW PHENYLTETRAHYDROTHIAZOLES, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
DE2147857A DE2147857C2 (en) | 1971-09-24 | 1971-09-24 | Substituted 6-phenyl-imidazo [2,1-b] -thiazoles, process for their preparation and anthelmintic agents containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2153206A2 true FR2153206A2 (en) | 1973-05-04 |
FR2153206B2 FR2153206B2 (en) | 1975-10-31 |
Family
ID=27159388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7134517A Granted FR2153206A2 (en) | 1971-09-24 | 1971-09-24 | Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE773062R (en) |
DE (1) | DE2147857C2 (en) |
FR (1) | FR2153206A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4018932A (en) | 1975-11-03 | 1977-04-19 | American Cyanamid Company | Anthelmintic pour-on formulations for topical use on domestic and farm animals |
GB1516938A (en) * | 1976-05-01 | 1978-07-05 | Pfizer Ltd | Halopyridylamides of m-aminotetramisole and their use as anthelmintics |
EP0041322A1 (en) * | 1980-05-30 | 1981-12-09 | Beecham Group Plc | m-Pyrazolylamido tetramisole derivatives, compositions thereof, processes for production of such compounds and compositions and their use in treating helminthiasis |
GR74993B (en) * | 1980-08-16 | 1984-07-12 | Beecham Group Ltd |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3463786A (en) * | 1967-12-19 | 1969-08-26 | American Cyanamid Co | Method of resolving dl 6 - phenyl - 2,3,5,6-tetrahydroimidazo(2,1-b) - thiazole and novel compounds resulting therefrom |
-
1971
- 1971-09-24 FR FR7134517A patent/FR2153206A2/en active Granted
- 1971-09-24 BE BE773062A patent/BE773062R/en active
- 1971-09-24 DE DE2147857A patent/DE2147857C2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2153206B2 (en) | 1975-10-31 |
BE773062R (en) | 1972-03-24 |
DE2147857C2 (en) | 1985-09-12 |
DE2147857A1 (en) | 1973-05-30 |
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