FR2205318A2 - 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls - Google Patents

6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls

Info

Publication number
FR2205318A2
FR2205318A2 FR7239731A FR7239731A FR2205318A2 FR 2205318 A2 FR2205318 A2 FR 2205318A2 FR 7239731 A FR7239731 A FR 7239731A FR 7239731 A FR7239731 A FR 7239731A FR 2205318 A2 FR2205318 A2 FR 2205318A2
Authority
FR
France
Prior art keywords
substd
anticonvuls
tranquillizers
pyrazines
carbonyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7239731A
Other languages
French (fr)
Other versions
FR2205318B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to FR7239731A priority Critical patent/FR2205318A2/en
Priority to OA54780A priority patent/OA04285A/en
Priority to PL17454072A priority patent/PL91760B1/pl
Priority to DD167951A priority patent/DD102698A5/xx
Priority to NL7217852A priority patent/NL7217852A/xx
Priority to US319876A priority patent/US3862149A/en
Priority to IE12/73A priority patent/IE37056B1/en
Priority to IL41232A priority patent/IL41232A/en
Priority to AU50754/73A priority patent/AU466586B2/en
Priority to HURO691A priority patent/HU164821B/hu
Priority to SE7300159A priority patent/SE398503B/en
Priority to GB79073A priority patent/GB1358680A/en
Priority to CA160,620A priority patent/CA991183A/en
Priority to CS499676A priority patent/CS180650B2/en
Priority to LU66800A priority patent/LU66800A1/xx
Priority to ES410372A priority patent/ES410372A1/en
Priority to DK6973AA priority patent/DK139359B/en
Priority to CH1160774A priority patent/CH560703A5/xx
Priority to CY915A priority patent/CY915A/en
Priority to BE793730D priority patent/BE793730A/en
Priority to JP48000069A priority patent/JPS523952B2/ja
Priority to FI27/73A priority patent/FI54124C/en
Priority to DE2300491A priority patent/DE2300491C3/en
Priority to AR246000A priority patent/AR195097A1/en
Priority to AT10073A priority patent/AT323181B/en
Priority to NO62/73A priority patent/NO136843C/en
Priority to AR24966273A priority patent/AR195636A1/en
Priority to SU1993903A priority patent/SU507240A3/en
Publication of FR2205318A2 publication Critical patent/FR2205318A2/en
Application granted granted Critical
Publication of FR2205318B2 publication Critical patent/FR2205318B2/fr
Priority to JP51106832A priority patent/JPS5248688A/en
Priority to JP51106831A priority patent/JPS5248687A/en
Priority to HK600/77A priority patent/HK60077A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

Title cpds. are of formula (I): where Q = A = Ph, pyridyl, pyridazinyl, or 2-, 3- or 4-quinolyl, all opt. substd. by >=1 hal, 1-4 C alkyl, 1-4 C alkoxy, CN or NO2; and n = 0 or 1; and salts of (I). (I) are prepd. e.g., by condensing QOH with ClCOZ in presence of a base.
FR7239731A 1972-01-07 1972-11-09 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls Granted FR2205318A2 (en)

Priority Applications (31)

Application Number Priority Date Filing Date Title
FR7239731A FR2205318A2 (en) 1972-11-09 1972-11-09 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls
OA54780A OA04285A (en) 1972-01-07 1972-12-14 New derivatives of pyrrolo (3,4-b) pyrazine and their preparation.
PL17454072A PL91760B1 (en) 1972-11-09 1972-12-28
DD167951A DD102698A5 (en) 1972-01-07 1972-12-28
NL7217852A NL7217852A (en) 1972-01-07 1972-12-29
US319876A US3862149A (en) 1972-01-07 1972-12-29 Pyrrolo (3,4-b) pyrazine derivatives
IL41232A IL41232A (en) 1972-01-07 1973-01-04 Pyrrolo(3,4-b)pyrazine derivatives,processes for their preparation and pharmaceutical preparations containing the same
AU50754/73A AU466586B2 (en) 1972-01-07 1973-01-04 Pyrolo (3,4-6) pyrazine derivatives
HURO691A HU164821B (en) 1972-01-07 1973-01-04
IE12/73A IE37056B1 (en) 1972-01-07 1973-01-04 Pyrrolo(3,4-b)pyrazine derivatives
CH1160774A CH560703A5 (en) 1972-11-09 1973-01-05
CA160,620A CA991183A (en) 1972-01-07 1973-01-05 Pyrrolo (3,4-b) pyrazine derivatives, their preparation and pharmaceutical compositions containing them
CS499676A CS180650B2 (en) 1972-11-09 1973-01-05 Process for preparing new derivatives of pyrrolo /3,4-b0 pyrazine
LU66800A LU66800A1 (en) 1972-01-07 1973-01-05
ES410372A ES410372A1 (en) 1972-11-09 1973-01-05 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls
DK6973AA DK139359B (en) 1972-01-07 1973-01-05 Analogous process for the preparation of pyrrolo (3,4-b) -pyrazine derivatives, or acid addition salts thereof.
SE7300159A SE398503B (en) 1972-01-07 1973-01-05 ANALOGICAL PROCEDURE FOR THE PREPARATION OF 5,6-DIHYDRO-PYRROLO (3,4-B) PYRAZIN DERIVATIVES
CY915A CY915A (en) 1972-01-07 1973-01-05 Pyrrolo (3,4-b) pyrazine derivatives
GB79073A GB1358680A (en) 1972-01-07 1973-01-05 Pyrrolo-3,4-b-pyrazine derivatives
JP48000069A JPS523952B2 (en) 1972-01-07 1973-01-05
FI27/73A FI54124C (en) 1972-01-07 1973-01-05 FRUIT PROTECTION FOR THERAPEUTIC USE OF THERAPEUTIC ANVAENDBARA 5- (4-METHYL-1-PIPERAZINYL) -CARBONYLOXY-7-OXO-5,6-DIHYDROPYRROLO (3,4-B) PYRAZINE DERIVATIVES
DE2300491A DE2300491C3 (en) 1972-01-07 1973-01-05 Pyrroles »[3,4-b] pyrazine derivatives, their preparation and pharmaceutical compositions
AR246000A AR195097A1 (en) 1972-01-07 1973-01-05 PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF PIRROLO (3,4-B) PIRAZINE
AT10073A AT323181B (en) 1972-01-07 1973-01-05 PROCESS FOR THE PREPARATION OF NEW PYRROLO (3,4-B) PYRAZINE DERIVATIVES AND THEIR ACID ADDITION SALTS
NO62/73A NO136843C (en) 1972-01-07 1973-01-05 ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE DERIVATIVES OF 5,6-DIHYDRO-PYRROLO (3,4-B) PYRAZINE
BE793730D BE793730A (en) 1972-01-07 1973-01-05 NEW PYRROLO (3,4-B) PYRAZINE DERIVATIVES, THEIR PREPARATION AND THEIR MEDICINAL COMPOSITIONS CONTAINING THEM
AR24966273A AR195636A1 (en) 1972-11-09 1973-08-21 PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF PIRROLO <3,4-B> PIRAZINE
SU1993903A SU507240A3 (en) 1972-11-09 1974-02-06 The method of obtaining derivatives of pyrrolo / 3,4-in / pyrazine or their salts
JP51106831A JPS5248687A (en) 1972-01-07 1976-09-08 Production of pyroro *3*44b* pyrazine derivative
JP51106832A JPS5248688A (en) 1972-01-07 1976-09-08 Production of pyroro *3*44b* pyrazine derivative
HK600/77A HK60077A (en) 1972-01-07 1977-12-01 Pyrrolo (3,4-b) pyrazine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7239731A FR2205318A2 (en) 1972-11-09 1972-11-09 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls

Publications (2)

Publication Number Publication Date
FR2205318A2 true FR2205318A2 (en) 1974-05-31
FR2205318B2 FR2205318B2 (en) 1975-11-28

Family

ID=9106900

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7239731A Granted FR2205318A2 (en) 1972-01-07 1972-11-09 6-substd 5-(4-methyl 1-piperazinyl)carbonyloxy 7-oxo - 5,6-dihydro-pyrrolo (3,4-b)pyrazines - tranquillizers and anticonvuls

Country Status (7)

Country Link
AR (1) AR195636A1 (en)
CH (1) CH560703A5 (en)
CS (1) CS180650B2 (en)
ES (1) ES410372A1 (en)
FR (1) FR2205318A2 (en)
PL (1) PL91760B1 (en)
SU (1) SU507240A3 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7111074A (en) * 1970-08-19 1972-02-22
NL7116737A (en) * 1970-12-14 1972-06-16
NL7205656A (en) * 1971-05-04 1972-11-07

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7111074A (en) * 1970-08-19 1972-02-22
NL7116737A (en) * 1970-12-14 1972-06-16
NL7205656A (en) * 1971-05-04 1972-11-07

Also Published As

Publication number Publication date
ES410372A1 (en) 1975-12-01
SU507240A3 (en) 1976-03-15
CH560703A5 (en) 1975-04-15
PL91760B1 (en) 1977-03-31
AR195636A1 (en) 1973-10-23
CS180650B2 (en) 1977-08-31
FR2205318B2 (en) 1975-11-28

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