FR2139045A1 - Phenylalanine derivs racemization - by heating in aqueous suspension - Google Patents

Phenylalanine derivs racemization - by heating in aqueous suspension

Info

Publication number
FR2139045A1
FR2139045A1 FR7218705A FR7218705A FR2139045A1 FR 2139045 A1 FR2139045 A1 FR 2139045A1 FR 7218705 A FR7218705 A FR 7218705A FR 7218705 A FR7218705 A FR 7218705A FR 2139045 A1 FR2139045 A1 FR 2139045A1
Authority
FR
France
Prior art keywords
heating
optically active
derivs
racemization
phenylalanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7218705A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynamit Nobel AG
Original Assignee
Dynamit Nobel AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712126049 external-priority patent/DE2126049C/en
Application filed by Dynamit Nobel AG filed Critical Dynamit Nobel AG
Publication of FR2139045A1 publication Critical patent/FR2139045A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Optically active phenylalanines of formula (I): (where R is H or lower alkyl) are racemised by heating in aqs. suspension to 150-200 degrees C (pref. 170-180 degrees C) under presure. Since it is not necessary to completely dissolve the optically active, (I), relatively large amounts can be subjected to the racemisation procedure, and energy and equipment costs are reduced. Isolation of the racemate is considerably simplified if the suspended racemate is simply filtered off and the mother liquor used for preparing a new suspension of optically active (I).
FR7218705A 1971-05-26 1972-05-25 Phenylalanine derivs racemization - by heating in aqueous suspension Withdrawn FR2139045A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712126049 DE2126049C (en) 1971-05-26 Process for racemizing an optically active phenylalanine

Publications (1)

Publication Number Publication Date
FR2139045A1 true FR2139045A1 (en) 1973-01-05

Family

ID=5808919

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7218705A Withdrawn FR2139045A1 (en) 1971-05-26 1972-05-25 Phenylalanine derivs racemization - by heating in aqueous suspension

Country Status (2)

Country Link
ES (1) ES403181A1 (en)
FR (1) FR2139045A1 (en)

Also Published As

Publication number Publication date
DE2126049A1 (en) 1972-10-05
ES403181A1 (en) 1975-05-01

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Legal Events

Date Code Title Description
ST Notification of lapse