FR2137898A1 - Alpha-oximino-penicillins - with antibacterial activity - Google Patents

Alpha-oximino-penicillins - with antibacterial activity

Info

Publication number
FR2137898A1
FR2137898A1 FR7217282A FR7217282A FR2137898A1 FR 2137898 A1 FR2137898 A1 FR 2137898A1 FR 7217282 A FR7217282 A FR 7217282A FR 7217282 A FR7217282 A FR 7217282A FR 2137898 A1 FR2137898 A1 FR 2137898A1
Authority
FR
France
Prior art keywords
alpha
antibacterial activity
oximino
penicillins
acylamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7217282A
Other languages
English (en)
French (fr)
Other versions
FR2137898B1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1508271A external-priority patent/GB1399086A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of FR2137898A1 publication Critical patent/FR2137898A1/fr
Application granted granted Critical
Publication of FR2137898B1 publication Critical patent/FR2137898B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/14Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
FR7217282A 1971-05-14 1972-05-15 Alpha-oximino-penicillins - with antibacterial activity Granted FR2137898A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1508271A GB1399086A (en) 1971-05-14 1971-05-14 Cephalosporin compounds

Publications (2)

Publication Number Publication Date
FR2137898A1 true FR2137898A1 (en) 1972-12-29
FR2137898B1 FR2137898B1 (enrdf_load_stackoverflow) 1976-04-16

Family

ID=10052709

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7217282A Granted FR2137898A1 (en) 1971-05-14 1972-05-15 Alpha-oximino-penicillins - with antibacterial activity
FR7537636A Granted FR2287231A1 (fr) 1971-05-14 1975-12-09 Acides a (oximino etherifie) carboxyliques et leurs derives

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7537636A Granted FR2287231A1 (fr) 1971-05-14 1975-12-09 Acides a (oximino etherifie) carboxyliques et leurs derives

Country Status (14)

Country Link
JP (1) JPS5248997B1 (enrdf_load_stackoverflow)
AT (1) AT329176B (enrdf_load_stackoverflow)
AU (2) AU474163B2 (enrdf_load_stackoverflow)
BE (1) BE783448A (enrdf_load_stackoverflow)
CH (1) CH579571A5 (enrdf_load_stackoverflow)
DE (1) DE2223287A1 (enrdf_load_stackoverflow)
ES (1) ES402650A1 (enrdf_load_stackoverflow)
FR (2) FR2137898A1 (enrdf_load_stackoverflow)
HU (1) HU172017B (enrdf_load_stackoverflow)
IE (1) IE37782B1 (enrdf_load_stackoverflow)
IL (1) IL39428A (enrdf_load_stackoverflow)
NL (1) NL7206466A (enrdf_load_stackoverflow)
PL (1) PL101031B1 (enrdf_load_stackoverflow)
ZA (2) ZA723223B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204404A2 (enrdf_load_stackoverflow) * 1972-10-25 1974-05-24 Glaxo Lab Ltd

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008000560A (es) 2005-07-11 2008-03-10 Mitsubishi Tanabe Pharma Corp Un derivado de oxima y sus preparaciones.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159449B (de) * 1961-03-22 1963-12-19 Gruenenthal Chemie Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2542812A (en) * 1946-04-03 1951-02-20 Walter H Hartung Preparation of aminoacidamides
SE311519B (enrdf_load_stackoverflow) * 1962-12-14 1969-06-16 Astra Ab

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159449B (de) * 1961-03-22 1963-12-19 Gruenenthal Chemie Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204404A2 (enrdf_load_stackoverflow) * 1972-10-25 1974-05-24 Glaxo Lab Ltd

Also Published As

Publication number Publication date
AT329176B (de) 1976-04-26
NL7206466A (enrdf_load_stackoverflow) 1972-11-16
PL101031B1 (pl) 1978-11-30
ATA420772A (de) 1975-07-15
AU474163B2 (en) 1976-07-15
CH579571A5 (enrdf_load_stackoverflow) 1976-09-15
IE37782L (en) 1972-11-14
AU4229972A (en) 1973-12-20
HU172017B (hu) 1978-05-28
DE2223287A1 (de) 1972-12-07
IL39428A (en) 1977-01-31
FR2137898B1 (enrdf_load_stackoverflow) 1976-04-16
BE783448A (fr) 1972-11-13
IE37782B1 (en) 1977-10-12
ZA723224B (en) 1973-03-28
IL39428A0 (en) 1972-07-26
AU4229872A (en) 1974-01-03
AU475444B2 (en) 1976-08-26
FR2287231A1 (fr) 1976-05-07
ZA723223B (en) 1973-02-28
JPS5248997B1 (enrdf_load_stackoverflow) 1977-12-14
FR2287231B1 (enrdf_load_stackoverflow) 1978-09-01
ES402650A1 (es) 1976-01-01

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