FR2130503A1 - S-epimer of 20-ethyl-9alpha, 11 alpha, 15-trihydroxy-5-cis-13-trans - prostadienic acid prodn from p-phenylbenzoate esters - Google Patents
S-epimer of 20-ethyl-9alpha, 11 alpha, 15-trihydroxy-5-cis-13-trans - prostadienic acid prodn from p-phenylbenzoate estersInfo
- Publication number
- FR2130503A1 FR2130503A1 FR7209844A FR7209844A FR2130503A1 FR 2130503 A1 FR2130503 A1 FR 2130503A1 FR 7209844 A FR7209844 A FR 7209844A FR 7209844 A FR7209844 A FR 7209844A FR 2130503 A1 FR2130503 A1 FR 2130503A1
- Authority
- FR
- France
- Prior art keywords
- epimer
- phenylbenzoate
- 9alpha
- trihydroxy
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- NNJMFJSKMRYHSR-UHFFFAOYSA-N 4-phenylbenzoic acid Chemical class C1=CC(C(=O)O)=CC=C1C1=CC=CC=C1 NNJMFJSKMRYHSR-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 2
- 229940093499 ethyl acetate Drugs 0.000 abstract 2
- 235000019439 ethyl acetate Nutrition 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 230000003529 luteolytic effect Effects 0.000 abstract 1
- -1 p-phenylbenzoate ester Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB746971A GB1356582A (en) | 1971-03-22 | 1971-03-22 | Process for the manufacture of prostadienoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2130503A1 true FR2130503A1 (en) | 1972-11-03 |
Family
ID=9833705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7209844A Withdrawn FR2130503A1 (en) | 1971-03-22 | 1972-03-21 | S-epimer of 20-ethyl-9alpha, 11 alpha, 15-trihydroxy-5-cis-13-trans - prostadienic acid prodn from p-phenylbenzoate esters |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE781079A (enrdf_load_stackoverflow) |
| DE (1) | DE2213907A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2130503A1 (enrdf_load_stackoverflow) |
| HU (1) | HU163889B (enrdf_load_stackoverflow) |
| NL (1) | NL7203809A (enrdf_load_stackoverflow) |
| ZA (1) | ZA721159B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL42373A (en) * | 1972-06-02 | 1977-08-31 | Pfizer | Oxaprostagliandins and their preparation |
-
1972
- 1972-02-21 ZA ZA721159A patent/ZA721159B/xx unknown
- 1972-03-21 FR FR7209844A patent/FR2130503A1/fr not_active Withdrawn
- 1972-03-22 HU HUIE496A patent/HU163889B/hu unknown
- 1972-03-22 NL NL7203809A patent/NL7203809A/xx unknown
- 1972-03-22 BE BE781079A patent/BE781079A/xx unknown
- 1972-03-22 DE DE19722213907 patent/DE2213907A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE781079A (fr) | 1972-09-22 |
| NL7203809A (enrdf_load_stackoverflow) | 1972-09-26 |
| ZA721159B (en) | 1972-12-27 |
| HU163889B (enrdf_load_stackoverflow) | 1973-11-28 |
| DE2213907A1 (enrdf_load_stackoverflow) | 1972-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |