FR2113947A1 - Oral raubasine compositions - also contg polyethylene glycol to improve resorption - Google Patents
Oral raubasine compositions - also contg polyethylene glycol to improve resorptionInfo
- Publication number
- FR2113947A1 FR2113947A1 FR7140569A FR7140569A FR2113947A1 FR 2113947 A1 FR2113947 A1 FR 2113947A1 FR 7140569 A FR7140569 A FR 7140569A FR 7140569 A FR7140569 A FR 7140569A FR 2113947 A1 FR2113947 A1 FR 2113947A1
- Authority
- FR
- France
- Prior art keywords
- raubasine
- polyethylene glycol
- contg
- oral
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GRTOGORTSDXSFK-XJTZBENFSA-N ajmalicine Chemical compound C1=CC=C2C(CCN3C[C@@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 GRTOGORTSDXSFK-XJTZBENFSA-N 0.000 title abstract 3
- ZLQMRLSBXKQKMG-UHFFFAOYSA-N rauniticine Natural products COC(=O)C1=CC2CC3N(CCc4c3[nH]c5ccccc45)CC2C(C)O1 ZLQMRLSBXKQKMG-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002202 Polyethylene glycol Substances 0.000 title abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 229960005156 digoxin Drugs 0.000 abstract 1
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 229960003746 metildigoxin Drugs 0.000 abstract 1
- IYJMSDVSVHDVGT-PEQKVOOWSA-N metildigoxin Chemical compound O1[C@H](C)[C@@H](OC)[C@@H](O)C[C@@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O IYJMSDVSVHDVGT-PEQKVOOWSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702055930 DE2055930A1 (de) | 1970-11-13 | 1970-11-13 | Verbesserte orale Applikationsform von Raubasin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2113947A1 true FR2113947A1 (en) | 1972-06-30 |
| FR2113947B1 FR2113947B1 (cs) | 1975-10-31 |
Family
ID=5788038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7140569A Granted FR2113947A1 (en) | 1970-11-13 | 1971-11-12 | Oral raubasine compositions - also contg polyethylene glycol to improve resorption |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5511645B1 (cs) |
| AT (1) | AT309690B (cs) |
| DE (1) | DE2055930A1 (cs) |
| FR (1) | FR2113947A1 (cs) |
| NL (1) | NL7115494A (cs) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2204425A1 (cs) * | 1972-10-31 | 1974-05-24 | Hoechst Ag | |
| EP0381182A3 (en) * | 1989-01-31 | 1991-01-09 | Ipa Internationale Pharma Agentur Gmbh | An erosion-controlled release system for active agents and a process for its preparation |
| FR2671727A1 (fr) * | 1991-01-18 | 1992-07-24 | Nawrocki Thadee | Utilisation de la raubasine pour traiter un mauvais metabolisme de fer. |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311694A (en) | 1979-12-31 | 1982-01-19 | American Cyanamid Company | Amorphous coprecipitates of 4-(monoalkylamino) benzoic acid and derivatives and certain water-soluble materials |
-
1970
- 1970-11-13 DE DE19702055930 patent/DE2055930A1/de active Pending
-
1971
- 1971-11-11 NL NL7115494A patent/NL7115494A/xx unknown
- 1971-11-12 FR FR7140569A patent/FR2113947A1/fr active Granted
- 1971-11-12 AT AT979271A patent/AT309690B/de not_active IP Right Cessation
- 1971-11-13 JP JP9103871A patent/JPS5511645B1/ja active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2204425A1 (cs) * | 1972-10-31 | 1974-05-24 | Hoechst Ag | |
| EP0381182A3 (en) * | 1989-01-31 | 1991-01-09 | Ipa Internationale Pharma Agentur Gmbh | An erosion-controlled release system for active agents and a process for its preparation |
| FR2671727A1 (fr) * | 1991-01-18 | 1992-07-24 | Nawrocki Thadee | Utilisation de la raubasine pour traiter un mauvais metabolisme de fer. |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2055930A1 (de) | 1972-05-18 |
| JPS5511645B1 (cs) | 1980-03-26 |
| AT309690B (de) | 1973-08-27 |
| FR2113947B1 (cs) | 1975-10-31 |
| NL7115494A (cs) | 1972-05-16 |
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